"CD4 Immunoadhesins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
| Descriptor ID |
D016860
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| MeSH Number(s) |
D12.644.541.500.697.249 D12.776.124.486.485.538.500.249 D12.776.124.486.485.680.697.249 D12.776.124.790.651.538.500.249 D12.776.124.790.651.680.660.249 D12.776.377.715.548.538.500.249 D12.776.377.715.548.680.660.249 D12.776.395.550.200.230 D12.776.543.550.200.230 D12.776.828.300.200 D23.050.301.350.230
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "CD4 Immunoadhesins".
Below are MeSH descriptors whose meaning is more specific than "CD4 Immunoadhesins".
This graph shows the total number of publications written about "CD4 Immunoadhesins" by people in this website by year, and whether "CD4 Immunoadhesins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD4 Immunoadhesins" by people in Profiles.
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eCD4-Ig Variants That More Potently Neutralize HIV-1. J Virol. 2018 06 15; 92(12).
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eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients. PLoS Pathog. 2017 12; 13(12):e1006786.