"Heparin Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.
| Descriptor ID |
D019763
|
| MeSH Number(s) |
D08.811.520.241.700.512
|
| Concept/Terms |
Heparin Lyase- Heparin Lyase
- Lyase, Heparin
- Neutralase
- Heparinase I
- Heparin Eliminase
- Eliminase, Heparin
- Heparinase
|
Below are MeSH descriptors whose meaning is more general than "Heparin Lyase".
Below are MeSH descriptors whose meaning is more specific than "Heparin Lyase".
This graph shows the total number of publications written about "Heparin Lyase" by people in this website by year, and whether "Heparin Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Heparin Lyase" by people in Profiles.
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Shedding First Light on the Alveolar Epithelial Glycocalyx. Am J Respir Cell Mol Biol. 2018 09; 59(3):283-284.
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The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice. Blood Adv. 2018 06 12; 2(11):1300-1314.
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Phase I study of the heparanase inhibitor roneparstat: an innovative approach for ultiple myeloma therapy. Haematologica. 2018 10; 103(10):e469-e472.
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Levels of Matrix-Degrading Enzymes and Lubricin in Patients With Degenerative Joint Disease Requiring Arthroplasty. Clin Appl Thromb Hemost. 2018 Jan; 24(1):41-46.
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Heparin-like effect resistant to protamine in a child with haemorrhagic shock. Do we need heparinase? Blood Transfus. 2018 07; 16(4):394-396.
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Tissue factor-activated thromboelastograms in children undergoing cardiac surgery: baseline values and comparisons. Anesth Analg. 2003 Nov; 97(5):1289-1293.
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Low-density-lipoprotein binding by mast-cell granules. Demonstration of binding of apolipoprotein B to heparin proteoglycan of exocytosed granules. Biochem J. 1987 Jan 15; 241(2):583-9.