"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.
| Descriptor ID |
D047495
|
| MeSH Number(s) |
D12.776.826.239.588
|
| Concept/Terms |
PPAR gamma- PPAR gamma
- PPARgamma
- Thiazolidinedione Receptor
- Receptor, Thiazolidinedione
- Peroxisome Proliferator-Activated Receptor gamma
- Peroxisome Proliferator Activated Receptor gamma
|
Below are MeSH descriptors whose meaning is more general than "PPAR gamma".
Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".
This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 4 | 0 | 4 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 11 | 5 | 16 |
| 2018 | 5 | 4 | 9 |
| 2019 | 5 | 8 | 13 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR gamma" by people in Profiles.
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Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 2021 09; 35(9):e21801.
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Interplay of Opposing Effects of the WNT/ß-Catenin Pathway and PPAR? and Implications for SARS-CoV2 Treatment. Front Immunol. 2021; 12:666693.
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Gamma-oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID-19? Mol Cell Endocrinol. 2021 01 15; 520:111095.
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Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-? as Candidates for Cytokine Storm Modulation in COVID-19 Disease. Molecules. 2020 Apr 29; 25(9).
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Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. Antioxid Redox Signal. 2020 01 01; 32(1):1-17.
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Flow cytometry-based FRET identifies binding intensities in PPAR?1 protein-protein interactions in living cells. Theranostics. 2019; 9(19):5444-5463.
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Overexpression of tensin homolog deleted on chromosome ten (PTEN) by ciglitazone sensitizes doxorubicin-resistance leukemia cancer cells to treatment. J Cell Biochem. 2019 09; 120(9):15719-15729.
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Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy. Autoimmun Rev. 2019 Jul; 18(7):673-678.
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Supraphysiological Concentrations of Bisphenol A Alter the Expression of Extracellular Vesicle-Enriched miRNAs From Human Primary Granulosa Cells. Toxicol Sci. 2019 05 01; 169(1):5-13.
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Elevated AA/EPA Ratio Represents an Inflammatory Biomarker in Tumor Tissue of Metastatic Colorectal Cancer Patients. Int J Mol Sci. 2019 Apr 25; 20(8).