"CD27 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS where it plays a role in stimulating the proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES.
| Descriptor ID |
D053282
|
| MeSH Number(s) |
D12.644.276.374.750.030 D12.776.395.092 D12.776.467.374.750.030 D12.776.543.550.170 D23.529.374.750.030
|
| Concept/Terms |
CD27 Ligand- CD27 Ligand
- Ligand, CD27
- Antigens, CD70
- CD70 Antigens
- Tumor Necrosis Factor Ligand Superfamily Member 7
- CD27L Protein
- CD70 Antigen
- Antigen, CD70
- TNF Superfamily, Member 7
|
Below are MeSH descriptors whose meaning is more general than "CD27 Ligand".
Below are MeSH descriptors whose meaning is more specific than "CD27 Ligand".
This graph shows the total number of publications written about "CD27 Ligand" by people in this website by year, and whether "CD27 Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 3 | 4 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD27 Ligand" by people in Profiles.
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The immune system of children: the key to understanding SARS-CoV-2 susceptibility? Lancet Child Adolesc Health. 2020 06; 4(6):414-416.
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Anti-tumour necrosis factor-a antibodies and B cell homeostasis in human inflammatory bowel diseases. Int Immunopharmacol. 2018 Jan; 54:329-335.
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Anti-SIRPa antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci U S A. 2017 12 05; 114(49):E10578-E10585.
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Phase I Dose-Escalation Study of the Anti-CD70 Antibody ARGX-110 in Advanced Malignancies. Clin Cancer Res. 2017 Nov 01; 23(21):6411-6420.
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The role of CD27 in anti-viral T-cell immunity. Curr Opin Virol. 2017 02; 22:77-88.
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Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency. J Exp Med. 2017 01; 214(1):91-106.
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The expression of CD70 and CD80 by gene-modified tumor cells induces an antitumor response depending on the MHC status. Cancer Gene Ther. 2000 Dec; 7(12):1543-56.