Signal Recognition Particle
"Signal Recognition Particle" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).
| Descriptor ID |
D018271
|
| MeSH Number(s) |
D12.776.157.725.500.750.800 D12.776.664.962.500.750.800
|
| Concept/Terms |
Signal Recognition Particle- Signal Recognition Particle
- Particle, Signal Recognition
- Recognition Particle, Signal
- SRP (Signal Recognition Particle)
|
Below are MeSH descriptors whose meaning is more general than "Signal Recognition Particle".
Below are MeSH descriptors whose meaning is more specific than "Signal Recognition Particle".
This graph shows the total number of publications written about "Signal Recognition Particle" by people in this website by year, and whether "Signal Recognition Particle" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Signal Recognition Particle" by people in Profiles.
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SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses. Cell. 2020 11 25; 183(5):1325-1339.e21.
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Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing. Mol Cell Proteomics. 2020 09; 19(9):1503-1522.
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Development of Necrotizing Myopathy Following Interstitial Lung Disease with Anti-signal Recognition Particle Antibody. Intern Med. 2018 Jul 15; 57(14):2045-2049.
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Leishmania tropica isolates from non-healed and healed patients in Iran: A molecular typing and phylogenetic analysis. Microb Pathog. 2018 Mar; 116:124-129.
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Necrosis in anti-SRP+ and anti-HMGCR+myopathies: Role of autoantibodies and complement. Neurology. 2018 02 06; 90(6):e507-e517.
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[Necrotizing myopathy associated with anti-SRP auto-antibodies: transient efficacy of a therapeutic strategy associating plasma exchanges and rituximab]. Presse Med. 2012 Oct; 41(10):1035-7.
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Transport of the intracisternal A-type particle Gag polyprotein to the endoplasmic reticulum is mediated by the signal recognition particle. J Virol. 2003 Jun; 77(11):6293-304.
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Signal recognition particle-dependent insertion of coronavirus E1, an intracellular membrane glycoprotein. J Biol Chem. 1985 Apr 25; 260(8):4648-52.