"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
| Descriptor ID |
D054411
|
| MeSH Number(s) |
D12.776.543.750.650.500
|
| Concept/Terms |
Receptors, Leptin- Receptors, Leptin
- Leptin-Binding Protein
- Leptin Binding Protein
- Receptor, Leptin
- Leptin Receptor
- Antigens, CD295
- LEPR Protein
- OB Receptor
- Receptor, OB
- CD295 Antigens
- Leptin Receptors
OBRb Receptor- OBRb Receptor
- Receptor, OBRb
- Leptin Receptor, Large Isoform
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".
This graph shows the total number of publications written about "Receptors, Leptin" by people in this website by year, and whether "Receptors, Leptin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.
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As a matter of fat: Leptin, monocyte hyperactivation, and COVID-19: A commentary to "Leptin correlates with monocytes activation and severe condition in COVID-19 patients". J Leukoc Biol. 2021 07; 110(1):7-8.
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Leptin gene polymorphism (rs7799039; G2548A) is associated with changes in serum lipid concentrations during pregnancy: a prospective cohort study. Eur J Nutr. 2020 Aug; 59(5):1999-2009.
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Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling. Circ Heart Fail. 2019 01; 12(1):e005622.
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Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment. J Clin Endocrinol Metab. 2018 07 01; 103(7):2601-2612.
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Associations between obesity candidate gene polymorphisms (fat mass and obesity-associated (FTO), melanocortin-4 receptor (MC4R), leptin (LEP) and leptin receptor (LEPR)) and dietary intake in pregnant women. Br J Nutr. 2018 08; 120(4):454-463.
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Maternal Western diet age-specifically alters female offspring voluntary physical activity and dopamine- and leptin-related gene expression. FASEB J. 2017 12; 31(12):5371-5383.
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Dementia-like pathology in type-2 diabetes: A novel microRNA mechanism. Mol Cell Neurosci. 2017 04; 80:58-65.
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Polymorphisms of Leptin (G2548A) and Leptin Receptor (Q223R and K109R) Genes and Blood Pressure During Pregnancy and the Postpartum Period: A Cohort. Am J Hypertens. 2017 Feb; 30(2):130-140.
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The Effects of High-fat-diet Combined with Chronic Unpredictable Mild Stress on Depression-like Behavior and Leptin/LepRb in Male Rats. Sci Rep. 2016 10 14; 6:35239.
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ACTH and alpha-MSH inhibit leptin expression and secretion in 3T3-L1 adipocytes: model for a central-peripheral melanocortin-leptin pathway. Mol Cell Endocrinol. 2003 Feb 28; 200(1-2):99-109.