"Cytochrome P-450 CYP2E1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.
Descriptor ID |
D019392
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MeSH Number(s) |
D08.244.453.491.375 D08.811.682.662.582.338 D08.811.682.690.708.170.450.375 D12.776.422.220.453.491.375
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Concept/Terms |
Cytochrome P-450 CYP2E1- Cytochrome P-450 CYP2E1
- Cytochrome P 450 CYP2E1
- Cytochrome P-450-J
- Cytochrome P 450 J
- 4-Nitrophenol-2-Hydroxylase
- 4 Nitrophenol 2 Hydroxylase
- Dimethylnitrosamine N-Demethylase
- Dimethylnitrosamine N Demethylase
- Cytochrome P450 2E1
- N-Nitrosodimethylamine Demethylase
- N Nitrosodimethylamine Demethylase
- CYP 2E1
- Cytochrome P-450 IIE1
- Cytochrome P 450 IIE1
- CYP IIE1
- CYPIIE1
- Cytochrome P-450 (ALC)
- CYP2E1
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP2E1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP2E1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP2E1" by people in this website by year, and whether "Cytochrome P-450 CYP2E1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cytochrome P-450 CYP2E1" by people in Profiles.
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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways. Food Funct. 2020 Apr 30; 11(4):3516-3526.
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Effect modification of CPY2E1 and GSTZ1 genetic polymorphisms on associations between prenatal disinfection by-products exposure and birth outcomes. Environ Pollut. 2018 Dec; 243(Pt B):1126-1133.
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The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans. Arch Toxicol. 2018 06; 92(6):2137-2140.
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The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic proteins via PPARa down-regulation. Toxicology. 2017 06 15; 385:18-27.
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A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations. J Chem Inf Model. 2011 Dec 27; 51(12):3217-25.