"Genes, BRCA1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.
| Descriptor ID |
D019398
|
| MeSH Number(s) |
G05.360.340.024.340.375.249.100 G05.360.340.024.340.415.400.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Genes, BRCA1".
Below are MeSH descriptors whose meaning is more specific than "Genes, BRCA1".
This graph shows the total number of publications written about "Genes, BRCA1" by people in this website by year, and whether "Genes, BRCA1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 3 | 4 | 7 |
| 2019 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, BRCA1" by people in Profiles.
-
Management of early breast cancer during the COVID-19 pandemic in Brazil. Breast Cancer Res Treat. 2020 Nov; 184(2):637-647.
-
Chemotherapy directly followed by poly(ADP-ribose) polymerase inhibition as an alternative to surgery in patients with BRCA-mutated ovarian cancer: a potential management strategy in the era of coronavirus disease 2019. Am J Obstet Gynecol. 2020 09; 223(3):469-470.
-
Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 09 03; 322(9):857-867.
-
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 08 20; 322(7):652-665.
-
Film-Spotting chiral miniPEG-?PNA array for BRCA1 gene mutation detection. Biosens Bioelectron. 2019 Jul 01; 136:1-7.
-
Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. N Engl J Med. 2018 12 27; 379(26):2495-2505.
-
Knowledge regarding and patterns of genetic testing in patients newly diagnosed with breast cancer participating in the iCanDecide trial. Cancer. 2018 10 15; 124(20):4000-4009.
-
Hormone replacement therapy after prophylactic risk-reducing salpingo-oophorectomy and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A meta-analysis. Crit Rev Oncol Hematol. 2018 Dec; 132:111-115.
-
Interpreting the unknown. Nat Med. 2018 10; 24(10):1491.
-
Cutting-edge cancer drug hobbled by diagnostic test confusion. Nature. 2018 04; 556(7700):161-162.