"Vaccines, DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
| Descriptor ID |
D019444
|
| MeSH Number(s) |
D12.776.828.868.910 D20.215.894.865.910 D23.050.865.910
|
| Concept/Terms |
Vaccines, DNA- Vaccines, DNA
- Recombinant DNA Vaccines
- DNA Vaccines, Recombinant
- DNA Vaccines
- Naked DNA Vaccines
- DNA Vaccines, Naked
- Vaccines, Naked DNA
- Vaccines, Recombinant DNA
|
Below are MeSH descriptors whose meaning is more general than "Vaccines, DNA".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, DNA".
This graph shows the total number of publications written about "Vaccines, DNA" by people in this website by year, and whether "Vaccines, DNA" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 4 | 0 | 4 |
| 2005 | 4 | 6 | 10 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 3 | 4 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 3 | 1 | 4 |
| 2016 | 0 | 1 | 1 |
| 2017 | 18 | 16 | 34 |
| 2018 | 10 | 9 | 19 |
| 2019 | 4 | 4 | 8 |
| 2020 | 6 | 12 | 18 |
| 2021 | 7 | 6 | 13 |
To return to the timeline, click here.
Below are the most recent publications written about "Vaccines, DNA" by people in Profiles.
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Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination. Emerg Microbes Infect. 2021 Dec; 10(1):1390-1403.
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Nucleic acid vaccines and CpG oligodeoxynucleotides for allergen immunotherapy. Curr Opin Allergy Clin Immunol. 2021 12 01; 21(6):569-575.
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A novel DNA and protein combination COVID-19 vaccine formulation provides full protection against SARS-CoV-2 in rhesus macaques. Emerg Microbes Infect. 2021 Dec; 10(1):342-355.
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SARS-CoV-2 (Covid-19) vaccines structure, mechanisms and effectiveness: A review. Int J Biol Macromol. 2021 Oct 01; 188:740-750.
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Akiko Iwasaki-aiming at making vaccines better. Lancet Infect Dis. 2021 08; 21(8):1082.
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Are We Paving the Way to Dig Out of the "Pandemic Hole"? A Narrative Review on SARS-CoV-2 Vaccination: From Animal Models to Human Immunization. Med Sci (Basel). 2021 07 30; 9(3).
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COVID-19 vaccines. Curr Opin Immunol. 2021 08; 71:111-116.
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Potential Therapeutic Targets and Vaccine Development for SARS-CoV-2/COVID-19 Pandemic Management: A Review on the Recent Update. Front Immunol. 2021; 12:658519.
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One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model. Vaccine. 2021 08 09; 39(34):4885-4894.
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Immunogenic potential of DNA vaccine candidate, ZyCoV-D against SARS-CoV-2 in animal models. Vaccine. 2021 07 05; 39(30):4108-4116.