Receptor Tyrosine Kinase-like Orphan Receptors
"Receptor Tyrosine Kinase-like Orphan Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.
| Descriptor ID |
D057050
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.093 D12.776.543.750.630.233
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| Concept/Terms |
Receptor Tyrosine Kinase-like Orphan Receptors- Receptor Tyrosine Kinase-like Orphan Receptors
- Receptor Tyrosine Kinase like Orphan Receptors
- Neurotrophic Tyrosine Kinase, Receptor-related Proteins
- Neurotrophic Tyrosine Kinase, Receptor related Proteins
- NTRKR Receptors
- ROR Tyrosine Kinase Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptor Tyrosine Kinase-like Orphan Receptors".
Below are MeSH descriptors whose meaning is more specific than "Receptor Tyrosine Kinase-like Orphan Receptors".
This graph shows the total number of publications written about "Receptor Tyrosine Kinase-like Orphan Receptors" by people in this website by year, and whether "Receptor Tyrosine Kinase-like Orphan Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor Tyrosine Kinase-like Orphan Receptors" by people in Profiles.
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Purification and characterization of the extracellular region of human receptor tyrosine kinase like orphan receptor 2 (ROR2). Protein Expr Purif. 2019 06; 158:74-80.
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Selective modulation of Wnt-binding receptor tyrosine kinase ROR2 expression by human cytomegalovirus regulates trophoblast migration. J Gen Virol. 2019 01; 100(1):99-104.
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Receptor tyrosine kinase-like orphan receptor 1 (ROR-1): An emerging target for diagnosis and therapy of chronic lymphocytic leukemia. Biomed Pharmacother. 2017 Apr; 88:814-822.
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Antiproliferative and Apoptotic Effects of Novel Anti-ROR1 Single-Chain Antibodies in Hematological Malignancies. SLAS Discov. 2017 04; 22(4):408-417.
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Isolation and characterization of anti ROR1 single chain fragment variable antibodies using phage display technique. Hum Antibodies. 2017; 25(1-2):57-63.