Combinatorial Chemistry Techniques
"Combinatorial Chemistry Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A technology, in which sets of reactions for solution or solid-phase synthesis, is used to create molecular libraries for analysis of compounds on a large scale.
| Descriptor ID |
D020650
|
| MeSH Number(s) |
E05.197.312 J01.897.836.249.249
|
| Concept/Terms |
Combinatorial Chemistry Techniques- Combinatorial Chemistry Techniques
- Techniques, Combinatorial Chemistry
- Chemistry Technique, Combinatorial
- Combinatorial Chemistry Technique
- Technics, Combinatorial Chemistry
- Chemistry Technic, Combinatorial
- Chemistry Technics, Combinatorial
- Combinatorial Chemistry Technic
- Combinatorial Chemistry Technics
- Technic, Combinatorial Chemistry
- Chemistry Techniques, Combinatorial
- Technique, Combinatorial Chemistry
|
Below are MeSH descriptors whose meaning is more general than "Combinatorial Chemistry Techniques".
Below are MeSH descriptors whose meaning is more specific than "Combinatorial Chemistry Techniques".
This graph shows the total number of publications written about "Combinatorial Chemistry Techniques" by people in this website by year, and whether "Combinatorial Chemistry Techniques" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Combinatorial Chemistry Techniques" by people in Profiles.
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Targeting Ribosomal Frameshifting as an Antiviral Strategy: From HIV-1 to SARS-CoV-2. Acc Chem Res. 2021 09 07; 54(17):3349-3361.
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SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging. Nat Chem Biol. 2021 02; 17(2):222-228.
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De novo design, retrosynthetic analysis and combinatorial synthesis of a hybrid antiviral (VTAR-01) to inhibit the interaction of SARS-CoV2 spike glycoprotein with human angiotensin-converting enzyme 2. Biol Open. 2020 10 15; 9(10).
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Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library. Proc Natl Acad Sci U S A. 2020 07 21; 117(29):16782-16789.
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The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery. Essays Biochem. 2017 11 08; 61(5):495-503.
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Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks. ACS Chem Biol. 2017 10 20; 12(10):2644-2651.
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Production and characterization of egg yolk antibody (IgY) against recombinant VP8-S2 antigen. Pol J Vet Sci. 2016; 19(2):271-9.
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Sensitized detection of inhibitory fragments and iterative development of non-peptidic protease inhibitors by dynamic ligation screening. Angew Chem Int Ed Engl. 2008; 47(17):3275-8.
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Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters. J Med Chem. 2007 Apr 19; 50(8):1850-64.
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Development and validation of a high-throughput screen for inhibitors of SARS CoV and its application in screening of a 100,000-compound library. J Biomol Screen. 2007 Feb; 12(1):33-40.