"Sodium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
| Descriptor ID |
D026941
|
| MeSH Number(s) |
D27.505.519.562.750 D27.505.954.411.720
|
| Concept/Terms |
Sodium Channel Blockers- Sodium Channel Blockers
- Sodium Channel Inhibitors
- Channel Inhibitors, Sodium
- Inhibitors, Sodium Channel
- Channel Blockers, Sodium
|
Below are MeSH descriptors whose meaning is more general than "Sodium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Sodium Channel Blockers".
This graph shows the total number of publications written about "Sodium Channel Blockers" by people in this website by year, and whether "Sodium Channel Blockers" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium Channel Blockers" by people in Profiles.
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COVID-19-related arrhythmias and the possible effects of ranolazine. Med Hypotheses. 2021 Apr; 149:110545.
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Mechanistic insights into Nav1.7-dependent regulation of rat prostate cancer cell invasiveness revealed by toxin probes and proteomic analysis. FEBS J. 2019 07; 286(13):2549-2561.
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Ranolazine treatment in the heterogeneous symptomatic stable coronary artery disease population. J Cardiovasc Med (Hagerstown). 2018 04; 19(4):186-190.
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Sympathetic mechanisms in an animal model of vasovagal syncope. Clin Auton Res. 2018 06; 28(3):333-340.
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Efficacy of Ranolazine in Patients With Symptomatic Hypertrophic Cardiomyopathy: The RESTYLE-HCM Randomized, Double-Blind, Placebo-Controlled Study. Circ Heart Fail. 2018 01; 11(1):e004124.
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[The RIVER-PCI study]. G Ital Cardiol (Rome). 2017 Oct; 18(10):677-681.
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Pharmacologic Properties of Novel Local Anesthetic Agents in Anesthesia Practice. Anesthesiol Clin. 2017 Jun; 35(2):315-325.
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Hexamethylene amiloride blocks E protein ion channels and inhibits coronavirus replication. Virology. 2006 Sep 30; 353(2):294-306.
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Validation of coronavirus E proteins ion channels as targets for antiviral drugs. Adv Exp Med Biol. 2006; 581:573-8.