Receptors, Formyl Peptide
"Receptors, Formyl Peptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
| Descriptor ID |
D044042
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| MeSH Number(s) |
D12.776.543.750.695.235 D12.776.543.750.705.873 D12.776.543.750.750.340
|
| Concept/Terms |
Receptors, Formyl Peptide- Receptors, Formyl Peptide
- Formyl Peptide Receptors
- Peptide Receptors, Formyl
- FMLP Receptor
- Receptor, FMLP
- N-formyl Hexapeptide Receptor
- Hexapeptide Receptor, N-formyl
- N formyl Hexapeptide Receptor
- Receptor, N-formyl Hexapeptide
- N-Formylmethionyl Peptide Receptor
- N Formylmethionyl Peptide Receptor
- Peptide Receptor, N-Formylmethionyl
- Receptor, N-Formylmethionyl Peptide
- fMet-Leu-Phe Receptor
- Receptor, fMet-Leu-Phe
- fMet Leu Phe Receptor
- Formyl Peptide Receptor
- Receptor, Formyl Peptide
- Receptor, Chemotactic Peptide
- Chemotactic Peptide Receptor
- Peptide Receptor, Chemotactic
- F-Chemotactic Peptide Receptor
- F Chemotactic Peptide Receptor
- Receptor, F-Chemotactic Peptide
- Chemoattractant Receptor
- Receptor, Chemoattractant
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Below are MeSH descriptors whose meaning is more general than "Receptors, Formyl Peptide".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Formyl Peptide".
This graph shows the total number of publications written about "Receptors, Formyl Peptide" by people in this website by year, and whether "Receptors, Formyl Peptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2017 | 4 | 1 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Formyl Peptide" by people in Profiles.
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Discovery of potential imaging and therapeutic targets for severe inflammation in COVID-19 patients. Sci Rep. 2021 07 08; 11(1):14151.
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No impact of cancer and plague-relevant FPR1 polymorphisms on COVID-19. Oncoimmunology. 2020 12 08; 9(1):1857112.
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Formyl peptide receptor 1 signalling promotes experimental colitis in mice. Pharmacol Res. 2019 03; 141:591-601.
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N-Formyl Peptide Receptors Induce Radical Oxygen Production in Fibroblasts Derived From Systemic Sclerosis by Interacting With a Cleaved Form of Urokinase Receptor. Front Immunol. 2018; 9:574.
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Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury. JCI Insight. 2018 02 08; 3(3).
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Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells. J Exp Clin Cancer Res. 2017 Dec 08; 36(1):180.
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FPR2 promotes invasion and metastasis of gastric cancer cells and predicts the prognosis of patients. Sci Rep. 2017 06 09; 7(1):3153.
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Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome. Thorax. 2017 10; 72(10):928-936.
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Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas. Sci Rep. 2017 05 02; 7(1):1312.
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Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy. Diabetologia. 2017 04; 60(4):719-728.