Rho Guanine Nucleotide Exchange Factors
"Rho Guanine Nucleotide Exchange Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
| Descriptor ID |
D064067
|
| MeSH Number(s) |
D12.644.360.325.300.099 D12.776.476.325.300.099
|
| Concept/Terms |
Rho Guanine Nucleotide Exchange Factor 7- Rho Guanine Nucleotide Exchange Factor 7
- PAK-Interacting Exchange Factor beta
- PAK Interacting Exchange Factor beta
- Cool-1 Protein
- Cool 1 Protein
- Protein, Cool-1
- beta PIX Protein
- PIX Protein, beta
- Protein, beta PIX
- betaPIX Protein
- Protein, betaPIX
|
Below are MeSH descriptors whose meaning is more general than "Rho Guanine Nucleotide Exchange Factors".
Below are MeSH descriptors whose meaning is more specific than "Rho Guanine Nucleotide Exchange Factors".
This graph shows the total number of publications written about "Rho Guanine Nucleotide Exchange Factors" by people in this website by year, and whether "Rho Guanine Nucleotide Exchange Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Rho Guanine Nucleotide Exchange Factors" by people in Profiles.
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS One. 2018; 13(7):e0197561.
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Generalized epilepsy and mild intellectual disability associated with 13q34 deletion: A potential role for SOX1 and ARHGEF7. Seizure. 2018 Jul; 59:38-40.
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2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. J Hum Genet. 2017 Nov; 62(11):979-988.
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Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study. J Matern Fetal Neonatal Med. 2018 Aug; 31(16):2115-2121.
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The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier. Proc Natl Acad Sci U S A. 2017 06 06; 114(23):E4621-E4630.
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TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine. PLoS Pathog. 2013 Mar; 9(3):e1003232.
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The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration. J Biol Chem. 2009 Jun 05; 284(23):15771-80.