"Oncostatin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
| Descriptor ID |
D053683
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| MeSH Number(s) |
D12.644.276.374.562 D12.776.467.374.562 D23.529.374.562
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oncostatin M".
Below are MeSH descriptors whose meaning is more specific than "Oncostatin M".
This graph shows the total number of publications written about "Oncostatin M" by people in this website by year, and whether "Oncostatin M" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oncostatin M" by people in Profiles.
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Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery. Sci Rep. 2021 08 10; 11(1):16174.
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H3N2 influenza virus infection enhances oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 10 15; 371(2):322-329.
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Elevation of plasma oncostatin M in heart failure. Future Cardiol. 2017 05; 13(3):219-227.
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Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease. J Allergy Clin Immunol. 2017 Jun; 139(6):1966-1978.e9.
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Cooperation between monocytes and breast cancer cells promotes factors involved in cancer aggressiveness. Br J Cancer. 2003 Apr 22; 88(8):1207-12.
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Cyclooxygenase-2 activity is necessary for the angiogenic properties of oncostatin M. FEBS Lett. 1999 Oct 15; 459(3):453-7.