GATA4 Transcription Factor
"GATA4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.
| Descriptor ID |
D050991
|
| MeSH Number(s) |
D12.776.260.257.400 D12.776.930.314.400
|
| Concept/Terms |
GATA4 Transcription Factor- GATA4 Transcription Factor
- Transcription Factor, GATA4
- Transcription Factor GATA-4
- Factor GATA-4, Transcription
- GATA-4, Transcription Factor
- Transcription Factor GATA 4
- Transcription Factor GATA4
- Factor GATA4, Transcription
- GATA4, Transcription Factor
- GATA-4 Transcription Factor
- GATA 4 Transcription Factor
- Transcription Factor, GATA-4
|
Below are MeSH descriptors whose meaning is more general than "GATA4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA4 Transcription Factor".
This graph shows the total number of publications written about "GATA4 Transcription Factor" by people in this website by year, and whether "GATA4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "GATA4 Transcription Factor" by people in Profiles.
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[Association of single nucleotide polymorphisms of transcription factors with congenital heart diseases in the Chinese population: a Meta analysis]. Zhongguo Dang Dai Er Ke Za Zhi. 2018 Jun; 20(6):490-496.
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C/EBPß enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation. Nat Commun. 2018 04 30; 9(1):1739.
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Meox1 accelerates myocardial hypertrophic decompensation through Gata4. Cardiovasc Res. 2018 02 01; 114(2):300-311.
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GATA4 is highly expressed in childhood acute lymphoblastic leukemia, promotes cell proliferation and inhibits apoptosis by activating BCL2 and MDM2. Mol Med Rep. 2017 Nov; 16(5):6290-6298.
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Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve. Nat Commun. 2017 05 25; 8:15481.
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The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy. Cancer Res. 2007 Nov 01; 67(21):10428-35.