Wiskott-Aldrich Syndrome Protein
"Wiskott-Aldrich Syndrome Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cells. It is the founding member of the WASP protein family and interacts with CDC42 PROTEIN to help regulate ACTIN polymerization.
| Descriptor ID |
D051316
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| MeSH Number(s) |
D05.750.078.730.912.500 D12.776.220.525.912.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome Protein".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome Protein".
This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome Protein" by people in this website by year, and whether "Wiskott-Aldrich Syndrome Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome Protein" by people in Profiles.
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Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report. Front Immunol. 2020; 11:603428.
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Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study. Lancet Haematol. 2019 May; 6(5):e239-e253.
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Screening for Wiskott-Aldrich syndrome by flow cytometry. J Allergy Clin Immunol. 2018 07; 142(1):333-335.e8.
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Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in juvenile myelomonocytic leukemia patients. Hum Mutat. 2018 04; 39(4):579-587.
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Macrophages of patients with X-linked thrombocytopenia display an attenuated Wiskott-Aldrich syndrome phenotype. Immunol Cell Biol. 2003 Apr; 81(2):130-6.