"Caspase 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
| Descriptor ID |
D053454
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.920 D08.811.277.656.300.200.126.550.920 D12.644.360.075.405.550.920 D12.776.476.075.405.550.920
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspase 12".
Below are MeSH descriptors whose meaning is more specific than "Caspase 12".
This graph shows the total number of publications written about "Caspase 12" by people in this website by year, and whether "Caspase 12" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caspase 12" by people in Profiles.
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Protection against COVID-19 in African population: Immunology, genetics, and malaria clues for therapeutic targets. Virus Res. 2021 07 02; 299:198347.
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Increased expression of endoplasmic reticulum stress-related caspase-12 and CHOP in the hippocampus of EAE mice. Brain Res Bull. 2019 04; 147:174-182.
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An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12. Sci Rep. 2018 07 02; 8(1):9939.
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Caspase-12 and diabetic nephropathy: from mice to men? J Am Soc Nephrol. 2010 Jun; 21(6):886-8.
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Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem. 2006 Feb 03; 281(5):2693-700.
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Tula hantavirus triggers pro-apoptotic signals of ER stress in Vero E6 cells. Virology. 2005 Mar 01; 333(1):180-9.