"Cathepsin K" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
| Descriptor ID |
D056657
|
| MeSH Number(s) |
D08.811.277.656.224.405 D08.811.277.656.262.500.156 D08.811.277.656.300.200.156
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin K".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin K".
This graph shows the total number of publications written about "Cathepsin K" by people in this website by year, and whether "Cathepsin K" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin K" by people in Profiles.
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Pharmacoinformatics and hypothetical studies on allicin, curcumin, and gingerol as potential candidates against COVID-19-associated proteases. J Biomol Struct Dyn. 2022 Jan; 40(1):389-400.
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Different patterns of expression of cell cycle control and local invasion-related proteins in oral squamous cell carcinoma affecting young patients. J Oral Pathol Med. 2018 Jan; 47(1):32-39.
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Histochemical examination of the effects of high-dose 1,25(OH)2D3 on bone remodeling in young growing rats. J Mol Histol. 2016 Aug; 47(4):389-99.
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Safety and efficacy of the cathepsin K inhibitor ONO-5334 in postmenopausal osteoporosis: the OCEAN study. J Bone Miner Res. 2011 Jun; 26(6):1303-12.
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Running has a negative effect on bone metabolism and proinflammatory status in male aged rats. Exp Gerontol. 2008 Jun; 43(6):578-83.