Myeloid Cell Leukemia Sequence 1 Protein
"Myeloid Cell Leukemia Sequence 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
| Descriptor ID |
D064549
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| MeSH Number(s) |
D12.644.360.075.718.984 D12.776.476.075.718.968 D12.776.624.664.700.169.500
|
| Concept/Terms |
Myeloid Cell Leukemia Sequence 1 Protein- Myeloid Cell Leukemia Sequence 1 Protein
- Myeloid Cell Leukemia Sequence 1
- Myeloid Cell Factor-1
- Cell Factor-1, Myeloid
- Factor-1, Myeloid Cell
- Myeloid Cell Factor 1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1
|
Below are MeSH descriptors whose meaning is more general than "Myeloid Cell Leukemia Sequence 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Myeloid Cell Leukemia Sequence 1 Protein".
This graph shows the total number of publications written about "Myeloid Cell Leukemia Sequence 1 Protein" by people in this website by year, and whether "Myeloid Cell Leukemia Sequence 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Myeloid Cell Leukemia Sequence 1 Protein" by people in Profiles.
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SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production. Front Immunol. 2018; 9:787.
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Bcl-XL and Mcl-1 upregulation by calreticulin promotes apoptosis resistance of fibroblast-like synoviocytes via activation of PI3K/Akt and STAT3 pathways in rheumatoid arthritis. Clin Exp Rheumatol. 2018 Sep-Oct; 36(5):841-849.
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Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers. Cell Death Dis. 2018 01 17; 9(2):21.
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Enhancement of chemosensitivity by simultaneously silencing of Mcl-1 and Survivin genes using small interfering RNA in human myelomonocytic leukaemia. Artif Cells Nanomed Biotechnol. 2018 Dec; 46(8):1792-1798.
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development. Cancer Cell. 2017 09 11; 32(3):342-359.e10.
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MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1. Oncotarget. 2017 Mar 28; 8(13):22003-22013.
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Anti-tumor activity of PI3K-d inhibitor in hematologic malignant cells: Shedding new light on resistance to Idelalisib. Int J Biochem Cell Biol. 2017 04; 85:149-158.
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Molecular determinants of outcome in sorafenib-treated patients with hepatocellular carcinoma. J Cancer Res Clin Oncol. 2013 Jul; 139(7):1179-87.
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Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication. PLoS One. 2012; 7(1):e30191.
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MicroRNA 133B targets pro-survival molecules MCL-1 and BCL2L2 in lung cancer. Biochem Biophys Res Commun. 2009 Oct 23; 388(3):483-9.