Receptors, Prostaglandin E, EP4 Subtype
"Receptors, Prostaglandin E, EP4 Subtype" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of prostaglandin E receptors that specifically couples to GS ALPHA GTP-BINDING PROTEIN SUBUNITS and subsequently activates ADENYLYL CYCLASES. The receptor may also signal through the activation of PHOSPHATIDYLINOSITOL 3-KINASE.
Descriptor ID |
D058309
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MeSH Number(s) |
D12.776.543.750.695.200.700.600.400
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Concept/Terms |
Receptors, Prostaglandin E, EP4 Subtype- Receptors, Prostaglandin E, EP4 Subtype
- Prostaglandin E Receptor 4
- Prostaglandin EP4 Receptors
- EP4 Receptors, Prostaglandin
- Receptors, Prostaglandin EP4
- Prostanoid Receptor EP4
- EP4, Prostanoid Receptor
- Receptor EP4, Prostanoid
- Receptor, Prostaglandin EP4
- EP4 Receptor, Prostaglandin
- Prostaglandin EP4 Receptor
- PGE Receptor, EP4 Subtype
- Prostaglandin E2 Receptor, EP4 Subtype
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Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E, EP4 Subtype".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E, EP4 Subtype".
This graph shows the total number of publications written about "Receptors, Prostaglandin E, EP4 Subtype" by people in this website by year, and whether "Receptors, Prostaglandin E, EP4 Subtype" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2018 | 2 | 0 | 2 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin E, EP4 Subtype" by people in Profiles.
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Reciprocal interaction of HOTAIR and SP1 together enhance the ability of Xiaoji decoction and gefitinib to inhibit EP4 expression. J Ethnopharmacol. 2019 Jun 12; 237:128-140.
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EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 09; 1863(9):1029-1040.
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Prostaglandin E2 Inhibits Group 2 Innate Lymphoid Cell Activation and Allergic Airway Inflammation Through E-Prostanoid 4-Cyclic Adenosine Monophosphate Signaling. Front Immunol. 2018; 9:501.
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The properties of human CD40-activated B cells as antigen-presenting cells are not affected by PGE2. Oncol Rep. 2013 Mar; 29(3):1061-5.
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Association between prostaglandin E receptor subtype EP4 overexpression and unstable phenotype in atherosclerotic plaques in human. Arterioscler Thromb Vasc Biol. 2005 Sep; 25(9):1925-31.