"Proteolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cleavage of proteins into smaller peptides or amino acids either by PROTEASES or non-enzymatically (e.g., Hydrolysis). It does not include Protein Processing, Post-Translational.
| Descriptor ID |
D059748
|
| MeSH Number(s) |
G02.111.720 G03.812
|
| Concept/Terms |
Proteolysis- Proteolysis
- Proteolyses
- Protein Degradation
- Degradation, Protein
- Degradations, Protein
- Protein Degradations
Protein Digestion- Protein Digestion
- Digestion, Protein
- Digestions, Protein
- Protein Digestions
|
Below are MeSH descriptors whose meaning is more general than "Proteolysis".
Below are MeSH descriptors whose meaning is more specific than "Proteolysis".
This graph shows the total number of publications written about "Proteolysis" by people in this website by year, and whether "Proteolysis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 4 | 4 |
| 2014 | 1 | 8 | 9 |
| 2015 | 0 | 3 | 3 |
| 2016 | 1 | 9 | 10 |
| 2017 | 9 | 55 | 64 |
| 2018 | 12 | 31 | 43 |
| 2019 | 1 | 8 | 9 |
| 2020 | 0 | 13 | 13 |
| 2021 | 1 | 8 | 9 |
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Below are the most recent publications written about "Proteolysis" by people in Profiles.
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Qing-Fei-Pai-Du decoction and wogonoside exert anti-inflammatory action through down-regulating USP14 to promote the degradation of activating transcription factor 2. FASEB J. 2021 09; 35(9):e21870.
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ZMPSTE24 Regulates SARS-CoV-2 Spike Protein-enhanced Expression of Endothelial PAI-1. Am J Respir Cell Mol Biol. 2021 09; 65(3):300-308.
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Kallikreins emerge as new regulators of viral infections. Cell Mol Life Sci. 2021 Nov; 78(21-22):6735-6744.
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[Induced degradation of proteins by PROTACs and other strategies: towards promising drugs]. Biol Aujourdhui. 2021; 215(1-2):25-43.
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Evolutionary insights into the furin cleavage sites of SARS-CoV-2 variants from humans and animals. Arch Virol. 2021 Sep; 166(9):2541-2549.
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TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells. EMBO J. 2021 08 16; 40(16):e107821.
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Long-chain polyphosphates impair SARS-CoV-2 infection and replication. Sci Signal. 2021 07 06; 14(690).
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How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread? Viruses. 2021 06 25; 13(7).
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Full-Length Computational Model of the SARS-CoV-2 Spike Protein and Its Implications for a Viral Membrane Fusion Mechanism. Viruses. 2021 06 11; 13(6).
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Regulated Intramembrane Proteolysis of ACE2: A Potential Mechanism Contributing to COVID-19 Pathogenesis? Front Immunol. 2021; 12:612807.