"Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
| Descriptor ID |
D011486
|
| MeSH Number(s) |
D08.622.705 D12.776.124.650 D12.776.395.635 D23.113.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein C".
Below are MeSH descriptors whose meaning is more specific than "Protein C".
This graph shows the total number of publications written about "Protein C" by people in this website by year, and whether "Protein C" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2006 | 2 | 0 | 2 |
| 2009 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 6 | 4 | 10 |
| 2018 | 6 | 4 | 10 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "Protein C" by people in Profiles.
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Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity. Front Endocrinol (Lausanne). 2021; 12:658304.
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Hemostatic alterations linked to body fat distribution, fatty liver, and insulin resistance. Mol Metab. 2021 11; 53:101262.
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Low admission protein C levels are a risk factor for disease worsening and mortality in hospitalized patients with COVID-19. Thromb Res. 2021 08; 204:13-15.
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A pilot study on the impact of congenital thrombophilia in COVID-19. Eur J Clin Invest. 2021 May; 51(5):e13546.
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Old drug, new Trick? The rationale for the treatment of COVID-19 with activated protein C. Med Hypotheses. 2021 Apr; 149:110537.
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Minor Allele of Interferon-Induced Transmembrane Protein 3 Polymorphism (rs12252) Is Covered Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Mortality: A Worldwide Epidemiological Investigation. J Infect Dis. 2021 01 04; 223(1):175-178.
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Coagulation profile of COVID-19 patients admitted to the ICU: An exploratory study. PLoS One. 2020; 15(12):e0243604.
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Profile of natural anticoagulant, coagulant factor and anti-phospholipid antibody in critically ill COVID-19 patients. J Thromb Thrombolysis. 2020 Oct; 50(3):580-586.
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Interferon-Induced Transmembrane Protein 3 Related to Coronavirus Disease 2019. J Infect Dis. 2020 09 14; 222(8):1413.
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Revisiting the Protein C Pathway: An Opportunity for Adjunctive Intervention in COVID-19? Anesth Analg. 2020 09; 131(3):690-693.