"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
Descriptor ID |
D016207
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MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 1 | 3 |
1997 | 1 | 3 | 4 |
1998 | 1 | 1 | 2 |
1999 | 2 | 1 | 3 |
2000 | 3 | 0 | 3 |
2001 | 1 | 3 | 4 |
2002 | 2 | 6 | 8 |
2003 | 2 | 1 | 3 |
2004 | 1 | 5 | 6 |
2005 | 5 | 7 | 12 |
2006 | 1 | 7 | 8 |
2007 | 4 | 4 | 8 |
2008 | 8 | 12 | 20 |
2009 | 7 | 11 | 18 |
2010 | 4 | 6 | 10 |
2011 | 9 | 10 | 19 |
2012 | 7 | 15 | 22 |
2013 | 5 | 5 | 10 |
2014 | 2 | 10 | 12 |
2015 | 7 | 5 | 12 |
2016 | 7 | 25 | 32 |
2017 | 141 | 348 | 489 |
2018 | 114 | 308 | 422 |
2019 | 56 | 134 | 190 |
2020 | 101 | 229 | 330 |
2021 | 50 | 175 | 225 |
2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice. Emerg Microbes Infect. 2021 Dec; 10(1):1626-1637.
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Boosting with heterologous vaccines effectively improves protective immune responses of the inactivated SARS-CoV-2 vaccine. Emerg Microbes Infect. 2021 Dec; 10(1):1598-1608.
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The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences. Virulence. 2021 12; 12(1):1771-1794.
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Calming the cytokine storm in COVID-19. Nat Med. 2021 10; 27(10):1674-1675.
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Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2. Proc Natl Acad Sci U S A. 2021 09 21; 118(38).
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BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19. J Gerontol A Biol Sci Med Sci. 2021 09 13; 76(10):1775-1783.
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COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction. JCI Insight. 2021 09 08; 6(17).
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Type I, II, and III Interferon Signatures Correspond to Coronavirus Disease 2019 Severity. J Infect Dis. 2021 09 01; 224(5):777-782.
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Qing-Fei-Pai-Du decoction and wogonoside exert anti-inflammatory action through down-regulating USP14 to promote the degradation of activating transcription factor 2. FASEB J. 2021 09; 35(9):e21870.
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Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate. Curr Opin Rheumatol. 2021 09 01; 33(5):419-430.