"Receptors, Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors present on a wide variety of hematopoietic and non-hematopoietic cell types that are specific for INTERLEUKIN-4. They are involved in signaling a variety of immunological responses related to allergic INFLAMMATION including the differentiation of TH2 CELLS and the regulation of IMMUNOGLOBULIN E production. Two subtypes of receptors exist and are referred to as the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. Each receptor subtype is defined by its unique subunit composition.
| Descriptor ID |
D019948
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.360
|
| Concept/Terms |
Receptors, Interleukin-4- Receptors, Interleukin-4
- Receptors, Interleukin 4
- IL-4 Receptors
- IL 4 Receptors
- Receptors, IL-4
- Receptors, IL 4
- IL4 Receptors
- Receptors, IL4
- Interleukin 4 Receptor
- Receptor, Interleukin 4
- Interleukin-4 Receptors
- Interleukin 4 Receptors
- IL-4 Receptor
- IL 4 Receptor
- Receptor, IL-4
- IL4 Receptor
- Receptor, IL4
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Interleukin-4".
This graph shows the total number of publications written about "Receptors, Interleukin-4" by people in this website by year, and whether "Receptors, Interleukin-4" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptors, Interleukin-4" by people in Profiles.
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Spatial distribution of IL4 controls iNKT cell-DC crosstalk in tumors. Cell Mol Immunol. 2020 05; 17(5):496-506.
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Atopic Dermatitis: Collegium Internationale Allergologicum (CIA) Update 2019. Int Arch Allergy Immunol. 2019; 178(3):207-218.
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Impaired interleukin-4 signalling promotes establishment of Haemonchus contortus in sheep. Parasite Immunol. 2018 Dec; 40(12):e12597.
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Novel systemic drugs in treatment of atopic dermatitis: results from phase II and phase III studies published in 2017/2018. Curr Opin Allergy Clin Immunol. 2018 10; 18(5):432-437.
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The Anaphylatoxin C3a Receptor Expression on Human M2 Macrophages Is Down-Regulated by Stimulating the Histamine H4 Receptor and the IL-4 Receptor. J Innate Immun. 2018; 10(4):349-362.
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Targeting the interleukin-4 and interleukin-13 pathways in severe asthma: current knowledge and future needs. Curr Opin Pulm Med. 2018 01; 24(1):50-55.
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Dupilumab for the treatment of asthma. Expert Opin Biol Ther. 2017 12; 17(12):1565-1572.
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Dupilumab in the treatment of moderate-to-severe atopic dermatitis. Expert Rev Clin Immunol. 2017 04; 13(4):301-310.
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Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells. Immunobiology. 2017 05; 222(5):759-767.
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Association and gene-gene interactions of eight common single-nucleotide polymorphisms with pediatric asthma in middle china. J Asthma. 2010 Apr; 47(3):238-44.