"Peptide Nucleic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of deoxyribose groups. Peptide nucleic acids have high biological stability and higher affinity for complementary DNA or RNA sequences than analogous DNA oligomers.
| Descriptor ID |
D020135
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| MeSH Number(s) |
D13.695.578.424.550
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Nucleic Acids".
Below are MeSH descriptors whose meaning is more specific than "Peptide Nucleic Acids".
This graph shows the total number of publications written about "Peptide Nucleic Acids" by people in this website by year, and whether "Peptide Nucleic Acids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Peptide Nucleic Acids" by people in Profiles.
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Design and In-silico Screening of Peptide Nucleic Acid (PNA) Inspired Novel Pronucleotide Scaffolds Targeting COVID-19. Curr Comput Aided Drug Des. 2022; 18(1):26-40.
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Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma. PLoS One. 2020; 15(9):e0238089.
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A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma. Cancer Res. 2019 Dec 15; 79(24):6166-6177.
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Film-Spotting chiral miniPEG-?PNA array for BRCA1 gene mutation detection. Biosens Bioelectron. 2019 Jul 01; 136:1-7.
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Peptide Nucleic Acid Probe-Based Analysis as a New Detection Method for Clarithromycin Resistance in Helicobacter pylori. Gut Liver. 2018 11 15; 12(6):641-647.
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Fluorescence In Situ Hybridization (FISH) and Peptide Nucleic Acid Probe-Based FISH for Diagnosis of Q Fever Endocarditis and Vascular Infections. J Clin Microbiol. 2018 09; 56(9).
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A novel detection procedure for mutations in the 23S rRNA gene of Mycoplasma pneumoniae with peptide nucleic acid-mediated loop-mediated isothermal amplification assay. J Microbiol Methods. 2017 10; 141:90-96.
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Peptide Nucleic Acids as miRNA Target Protectors for the Treatment of Cystic Fibrosis. Molecules. 2017 Jul 08; 22(7).
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Peptide nucleic acids (PNAs): currently potential bactericidal agents. Biomed Pharmacother. 2017 Sep; 93:580-588.
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Multiplex Paper-Based Colorimetric DNA Sensor Using Pyrrolidinyl Peptide Nucleic Acid-Induced AgNPs Aggregation for Detecting MERS-CoV, MTB, and HPV Oligonucleotides. Anal Chem. 2017 05 16; 89(10):5428-5435.