"Gene Silencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
| Descriptor ID |
D020868
|
| MeSH Number(s) |
G05.308.203.374
|
| Concept/Terms |
Gene Silencing- Gene Silencing
- Silencing, Gene
- Gene Inactivation
- Inactivation, Gene
|
Below are MeSH descriptors whose meaning is more general than "Gene Silencing".
Below are MeSH descriptors whose meaning is more specific than "Gene Silencing".
This graph shows the total number of publications written about "Gene Silencing" by people in this website by year, and whether "Gene Silencing" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 4 | 6 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 2 | 2 |
| 2017 | 12 | 19 | 31 |
| 2018 | 9 | 22 | 31 |
| 2019 | 1 | 6 | 7 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Silencing" by people in Profiles.
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Clinical applications of thrombopoietin silencing: A possible therapeutic role in COVID-19? Cytokine. 2021 10; 146:155634.
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Designing an effective therapeutic siRNA to silence RdRp gene of SARS-CoV-2. Infect Genet Evol. 2021 09; 93:104951.
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A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19. Mol Ther. 2021 07 07; 29(7):2219-2226.
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B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells. Cell. 2021 04 01; 184(7):1790-1803.e17.
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Tmprss2 specific miRNAs as promising regulators for SARS-CoV-2 entry checkpoint. Virus Res. 2021 03; 294:198275.
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Prediction of potential small interfering RNA molecules for silencing of the spike gene of SARS-CoV-2. Indian J Med Res. 2021 Jan & Feb; 153(1 & 2):182-189.
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Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity. J Med Virol. 2021 04; 93(4):2406-2419.
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Micro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections. J Adv Res. 2021 05; 30:133-145.
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Computational Analysis of Targeting SARS-CoV-2, Viral Entry Proteins ACE2 and TMPRSS2, and Interferon Genes by Host MicroRNAs. Genes (Basel). 2020 11 16; 11(11).
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Newly Discovered Cellular Pathway Blocks Ebola, COVID-19 Viruses. JAMA. 2020 11 03; 324(17):1712.