Vascular Endothelial Growth Factor Receptor-1
"Vascular Endothelial Growth Factor Receptor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Descriptor ID |
D040281
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.950.100 D12.776.543.750.630.750.100 D12.776.543.750.750.400.910.100
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Concept/Terms |
Vascular Endothelial Growth Factor Receptor-1- Vascular Endothelial Growth Factor Receptor-1
- Vascular Endothelial Growth Factor Receptor 1
- FLT1 Receptor Tyrosine Kinase
- VEGF Receptor flt-1 Protein
- VEGF Receptor flt 1 Protein
- VEGFR-1
- fms-Like Tyrosine Kinase
- Tyrosine Kinase, fms-Like
- Proto-Oncogene Protein flt
- Proto Oncogene Protein flt
- FLT1 RTK
- VEGF Receptor, FLT
- FLT VEGF Receptor
- Receptor, FLT VEGF
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor Receptor-1".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor Receptor-1".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor Receptor-1" by people in this website by year, and whether "Vascular Endothelial Growth Factor Receptor-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 3 | 4 | 7 |
2018 | 7 | 2 | 9 |
2019 | 1 | 3 | 4 |
2020 | 2 | 0 | 2 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor Receptor-1" by people in Profiles.
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Diagnostic Significance of Serum Galectin-3 in Hospitalized Patients with COVID-19-A Preliminary Study. Biomolecules. 2021 08 01; 11(8).
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Excess Soluble fms-like Tyrosine Kinase 1 Correlates With Endothelial Dysfunction and Organ Failure in Critically Ill Coronavirus Disease 2019 Patients. Clin Infect Dis. 2021 05 18; 72(10):1834-1837.
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Soluble fms-like tyrosine kinase-1: a potential early predictor of respiratory failure in COVID-19 patients. Clin Chem Lab Med. 2021 06 25; 59(7):e289-e292.
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An immune-based biomarker signature is associated with mortality in COVID-19 patients. JCI Insight. 2021 01 11; 6(1).
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Increased sFLT-1/PlGF ratio in COVID-19: A novel link to angiotensin II-mediated endothelial dysfunction. Am J Hematol. 2020 08; 95(8):E188-E191.
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Pre-eclampsia-like syndrome induced by severe COVID-19: a prospective observational study. BJOG. 2020 10; 127(11):1374-1380.
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A Review of Angiogenic Imbalance in HIV-Infected Hypertensive Disorders of Pregnancy. Curr Hypertens Rep. 2019 07 24; 21(9):69.
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Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas). Clin Cancer Res. 2019 09 01; 25(17):5295-5300.
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Management of pregnancy blood pressure increase in the emergency room: role of PlGF-based biochemical markers and relative economic impact. J Matern Fetal Neonatal Med. 2021 Apr; 34(7):1083-1090.
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Postpartum blood pressure patterns in severe preeclampsia and normotensive pregnant women following abdominal deliveries: a cohort study. J Matern Fetal Neonatal Med. 2020 Sep; 33(18):3152-3162.