"Fatty Acid Desaturases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the stereoselective, regioselective, or chemoselective syn-dehydrogenation reactions. They function by a mechanism that is linked directly to reduction of molecular OXYGEN.
| Descriptor ID |
D044943
|
| MeSH Number(s) |
D08.811.682.690.708.392
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fatty Acid Desaturases".
Below are MeSH descriptors whose meaning is more specific than "Fatty Acid Desaturases".
This graph shows the total number of publications written about "Fatty Acid Desaturases" by people in this website by year, and whether "Fatty Acid Desaturases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Fatty Acid Desaturases" by people in Profiles.
-
Fatty Acid Desaturase Involvement in Non-Alcoholic Fatty Liver Disease Rat Models: Oxidative Stress Versus Metalloproteinases. Nutrients. 2019 Apr 08; 11(4).
-
Structural Determinants of Substrate Specificity of Omega-3 Desaturases from Mortierella alpina and Rhizophagus irregularis by Domain-Swapping and Molecular Docking. Int J Mol Sci. 2019 Mar 30; 20(7).
-
Molecular mechanism of substrate preference for ?-3 fatty acid desaturase from Mortierella alpina by mutational analysis and molecular docking. Appl Microbiol Biotechnol. 2018 Nov; 102(22):9679-9689.
-
In a pilot study, reduced fatty acid desaturase 1 function was associated with nonalcoholic fatty liver disease and response to treatment in children. Pediatr Res. 2018 11; 84(5):696-703.
-
Relationship of lipid regulatory gene polymorphisms and dyslipidemia in a pediatric population: the CASPIAN III study. Hormones (Athens). 2018 Mar; 17(1):97-105.
-
Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. J Med Genet. 2018 07; 55(7):459-468.
-
Substrate specificity and membrane topologies of the iron-containing ?3 and ?6 desaturases from Mortierella alpina. Appl Microbiol Biotechnol. 2018 Jan; 102(1):211-223.
-
The role of a FADS1 polymorphism in the association of fatty acid blood levels, BMI and blood pressure in young children-Analyses based on path models. PLoS One. 2017; 12(7):e0181485.
-
Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians. Nutr Neurosci. 2018 Oct; 21(8):589-601.
-
?3 fatty acid desaturases from microorganisms: structure, function, evolution, and biotechnological use. Appl Microbiol Biotechnol. 2013 Dec; 97(24):10255-62.