"PPAR delta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. It is activated by PROSTACYCLIN.
| Descriptor ID |
D047494
|
| MeSH Number(s) |
D12.776.826.239.555
|
| Concept/Terms |
PPAR delta- PPAR delta
- PPARdelta
- Peroxisome Proliferator-Activated Receptor delta
- Peroxisome Proliferator Activated Receptor delta
- PPARD protein
|
Below are MeSH descriptors whose meaning is more general than "PPAR delta".
Below are MeSH descriptors whose meaning is more specific than "PPAR delta".
This graph shows the total number of publications written about "PPAR delta" by people in this website by year, and whether "PPAR delta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2017 | 6 | 0 | 6 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "PPAR delta" by people in Profiles.
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Work in Progress: Drugs in Development. Clin Liver Dis. 2018 08; 22(3):501-515.
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Hepatic regulation of VLDL receptor by PPARß/d and FGF21 modulates non-alcoholic fatty liver disease. Mol Metab. 2018 02; 8:117-131.
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Parallel Chemistry Approach to Identify Novel Nuclear Receptor Ligands Based on the GW0742 Scaffold. ACS Comb Sci. 2017 10 09; 19(10):646-656.
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Seladelpar (MBX-8025), a selective PPAR-d agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study. Lancet Gastroenterol Hepatol. 2017 10; 2(10):716-726.
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PPARd Modulation by GW501516: An Unsuccessful Exercise Mimetic. Clin Pharmacol Ther. 2017 09; 102(3):395.
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PPARd activation protects H9c2 cardiomyoblasts from LPS-induced apoptosis through the heme oxygenase-1-mediated suppression of NF-?B activation. Mol Med Rep. 2017 Jun; 15(6):3775-3780.
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Association of polymorphisms of peroxisome proliferator activated receptors in early and late onset of type 2 diabetes mellitus. Diabetes Metab Syndr. 2017 Nov; 11 Suppl 1:S287-S293.
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On the mechanism for PPAR agonists to enhance ABCA1 gene expression. Atherosclerosis. 2009 Aug; 205(2):413-9.