"DEAD-box RNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of RNA helicases that share a common protein motif with the single letter amino acid sequence D-E-A-D (Asp-Glu-Ala-Asp). In addition to RNA helicase activity, members of the DEAD-box family participate in other aspects of RNA metabolism and regulation of RNA function.
| Descriptor ID |
D053487
|
| MeSH Number(s) |
D08.811.913.696.445.735.720.249
|
| Concept/Terms |
DEAD-box RNA Helicases- DEAD-box RNA Helicases
- DEAD box RNA Helicases
- Helicases, DEAD-box RNA
- RNA Helicases, DEAD-box
DEAD Box Helicase p68- DEAD Box Helicase p68
- p68 RNA Helicase
- Helicase, p68 RNA
- RNA Helicase, p68
- p68 DEAD Box Protein
|
Below are MeSH descriptors whose meaning is more general than "DEAD-box RNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DEAD-box RNA Helicases".
This graph shows the total number of publications written about "DEAD-box RNA Helicases" by people in this website by year, and whether "DEAD-box RNA Helicases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2017 | 1 | 5 | 6 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "DEAD-box RNA Helicases" by people in Profiles.
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The relative expression of miR-31, miR-29, miR-126, and miR-17 and their mRNA targets in the serum of COVID-19 patients with different grades during hospitalization. Eur J Med Res. 2021 Jul 13; 26(1):75.
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An isoform of Dicer protects mammalian stem cells against multiple RNA viruses. Science. 2021 07 09; 373(6551):231-236.
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Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection. Antiviral Res. 2021 06; 190:105064.
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SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells. Sci China Life Sci. 2020 09; 63(9):1413-1416.
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Herpes Simplex Virus Type 1-Encoded miR-H2-3p Manipulates Cytosolic DNA-Stimulated Antiviral Innate Immune Response by Targeting DDX41. Viruses. 2019 08 15; 11(8).
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FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing. Nature. 2019 01; 565(7740):500-504.
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Structures of RIG-I-Like Receptors and Insights into Viral RNA Sensing. Adv Exp Med Biol. 2019; 1172:157-188.
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Experimental Analysis of Mimivirus Translation Initiation Factor 4a Reveals Its Importance in Viral Protein Translation during Infection of Acanthamoeba polyphaga. J Virol. 2018 05 15; 92(10).
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RIG-I and Other RNA Sensors in Antiviral Immunity. Annu Rev Immunol. 2018 04 26; 36:667-694.
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Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals. Nucleic Acids Res. 2017 Dec 15; 45(22):e181.