"Off-Label Use" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
| Descriptor ID |
D056687
|
| MeSH Number(s) |
E02.319.307.500
|
| Concept/Terms |
Off-Label Use- Off-Label Use
- Off Label Use
- Off-Label Uses
- Use, Off-Label
- Uses, Off-Label
- Off-Label Prescribing
- Off Label Prescribing
- Off-Label Prescribings
- Prescribing, Off-Label
- Prescribings, Off-Label
- Unlabeled Indication
- Indication, Unlabeled
- Indications, Unlabeled
- Unlabeled Indications
|
Below are MeSH descriptors whose meaning is more general than "Off-Label Use".
Below are MeSH descriptors whose meaning is more specific than "Off-Label Use".
This graph shows the total number of publications written about "Off-Label Use" by people in this website by year, and whether "Off-Label Use" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 13 | 14 | 27 |
| 2018 | 13 | 9 | 22 |
| 2019 | 4 | 4 | 8 |
| 2020 | 6 | 9 | 15 |
| 2021 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Off-Label Use" by people in Profiles.
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A real-world study of immune thrombocytopenia management during the COVID-19 pandemic in the UK. Br J Haematol. 2022 01; 196(2):351-355.
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Real-World Use of Dalbavancin in the Era of Empowerment of Outpatient Antimicrobial Treatment: A Careful Appraisal Beyond Approved Indications Focusing on Unmet Clinical Needs. Drug Des Devel Ther. 2021; 15:3349-3378.
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SARS-CoV-2 attenuates corticosteroid sensitivity by suppressing DUSP1 expression and activating p38 MAPK pathway. Eur J Pharmacol. 2021 Oct 05; 908:174374.
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Managed care COVID-19 outcomes in a population health program. Am J Manag Care. 2021 06; 27(6):234-240.
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Assessment of Awareness and Experience of Using off-label Drugs by Doctors of Clinical Specialties. Kardiologiia. 2021 May 31; 61(5):41-50.
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Off-label tocilizumab and adjuvant iron chelator effectiveness in a group of severe COVID-19 pneumonia patients: A single center experience. Medicine (Baltimore). 2021 May 07; 100(18):e25832.
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[Drug use during the covid-19 pandemic in Italy.] Recenti Prog Med. 2021 05; 112(5):338-342.
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Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off-label in the first wave of COVID-19. Clin Transl Sci. 2021 05; 14(3):1133-1146.
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Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination. Nat Rev Immunol. 2021 05; 21(5):330-335.
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SAveRUNNER: an R-based tool for drug repurposing. BMC Bioinformatics. 2021 Mar 23; 22(1):150.