"Hepcidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
| Descriptor ID |
D064451
|
| MeSH Number(s) |
D12.776.494.249 D12.776.543.695.054.425
|
| Concept/Terms |
Hepcidins- Hepcidins
- Liver-Expressed Antimicrobial Peptide
- Antimicrobial Peptide, Liver-Expressed
- Liver Expressed Antimicrobial Peptide
- Peptide, Liver-Expressed Antimicrobial
- Hepcidin
|
Below are MeSH descriptors whose meaning is more general than "Hepcidins".
Below are MeSH descriptors whose meaning is more specific than "Hepcidins".
This graph shows the total number of publications written about "Hepcidins" by people in this website by year, and whether "Hepcidins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 1 | 2 |
| 2017 | 8 | 6 | 14 |
| 2018 | 5 | 6 | 11 |
| 2019 | 0 | 3 | 3 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepcidins" by people in Profiles.
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Antimicrobial peptides and other peptide-like therapeutics as promising candidates to combat SARS-CoV-2. Expert Rev Anti Infect Ther. 2021 10; 19(10):1205-1217.
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The relationship between serum erythropoietin, hepcidin, and haptoglobin levels with disease severity and other biochemical values in patients with COVID-19. Int J Lab Hematol. 2021 Jul; 43 Suppl 1:142-151.
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Cancer Related Anemia: An Integrated Multitarget Approach and Lifestyle Interventions. Nutrients. 2021 Feb 01; 13(2).
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Hepcidin is a friend rather than a foe in COVID19-induced complications. Acta Biomed. 2020 11 05; 91(4):e2020138.
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COVID-19 and NF-kB: The Hepcidin paradox and the Iron Storm - Reply. Acta Biomed. 2020 11 05; 91(4):e2020137.
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Hepcidin levels predict Covid-19 severity and mortality in a cohort of hospitalized Italian patients. Am J Hematol. 2021 01; 96(1):E32-E35.
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COVID-19 and iron dysregulation: distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein. Biol Direct. 2020 10 16; 15(1):19.
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Increased Serum Levels of Hepcidin and Ferritin Are Associated with Severity of COVID-19. Med Sci Monit. 2020 Sep 26; 26:e926178.
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Iron overload and Hepcidin overexpression could play a key role in COVID infection, and may explain vulnerability in elderly, diabetics, and obese patients. Acta Biomed. 2020 09 07; 91(3):e2020013.
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Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis. Eur J Epidemiol. 2020 Aug; 35(8):763-773.