Amy C Sims

InstitutionUniversity of North Carolina at Chapel Hill
AddressChapel Hill
North Carolina
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 6 Covid-19 publications, with a maximum of 1 publications in April 2020 and October 2020 and January 2021 and May 2021
    All Publications
    Bar chart showing 68 publications over 24 distinct years, with a maximum of 8 publications in 2006
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Reynolds D, Huesemann M, Edmundson S, Sims A, Hurst B, Cady S, Beirne N, Freeman J, Berger A, Gao S. Viral inhibitors derived from macroalgae, microalgae, and cyanobacteria: A review of antiviral potential throughout pathogenesis. Algal Res. 2021 Jul; 57:102331. PMID: 34026476.
      Citations: 1     
    2. Xu F, Gao J, Bergmann S, Sims AC, Ashbrook DG, Baric RS, Cui Y, Jonsson CB, Li K, Williams RW, Schughart K, Lu L. Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung. Front Immunol. 2020; 11:607314. PMID: 33488611.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Edwards CE, Yount BL, Graham RL, Leist SR, Hou YJ, Dinnon KH, Sims AC, Swanstrom J, Gully K, Scobey TD, Cooley MR, Currie CG, Randell SH, Baric RS. Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26915-26925. PMID: 33046644.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    4. Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 04 29; 12(541). PMID: 32253226.
      Citations: 271     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    5. Sheahan TP, Sims AC, Leist SR, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, Cihlar T, Jordan R, Denison MR, Baric RS. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nat Commun. 2020 01 10; 11(1):222. PMID: 31924756.
      Citations: 630     Fields:    Translation:HumansAnimalsCells
    6. Nicora CD, Sims AC, Bloodsworth KJ, Kim YM, Moore RJ, Kyle JE, Nakayasu ES, Metz TO. Metabolite, Protein, and Lipid Extraction (MPLEx): A Method that Simultaneously Inactivates Middle East Respiratory Syndrome Coronavirus and Allows Analysis of Multiple Host Cell Components Following Infection. Methods Mol Biol. 2020; 2099:173-194. PMID: 31883096.
      Citations: 6     Fields:    Translation:HumansCells
    7. Agostini ML, Pruijssers AJ, Chappell JD, Gribble J, Lu X, Andres EL, Bluemling GR, Lockwood MA, Sheahan TP, Sims AC, Natchus MG, Saindane M, Kolykhalov AA, Painter GR, Baric RS, Denison MR. Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance. J Virol. 2019 12 15; 93(24). PMID: 31578288.
      Citations: 57     Fields:    Translation:AnimalsCells
    8. Mitchell HD, Eisfeld AJ, Stratton KG, Heller NC, Bramer LM, Wen J, McDermott JE, Gralinski LE, Sims AC, Le MQ, Baric RS, Kawaoka Y, Waters KM. The Role of EGFR in Influenza Pathogenicity: Multiple Network-Based Approaches to Identify a Key Regulator of Non-lethal Infections. Front Cell Dev Biol. 2019; 7:200. PMID: 31616667.
      Citations: 6     
    9. Brown AJ, Won JJ, Graham RL, Dinnon KH, Sims AC, Feng JY, Cihlar T, Denison MR, Baric RS, Sheahan TP. Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase. Antiviral Res. 2019 09; 169:104541. PMID: 31233808.
      Citations: 159     Fields:    Translation:HumansAnimalsCells
    10. Beigel JH, Nam HH, Adams PL, Krafft A, Ince WL, El-Kamary SS, Sims AC. Advances in respiratory virus therapeutics - A meeting report from the 6th isirv Antiviral Group conference. Antiviral Res. 2019 07; 167:45-67. PMID: 30974127.
      Citations: 50     Fields:    Translation:HumansCellsPHPublic Health
    11. Chefer S, Seidel J, Cockrell AS, Yount B, Solomon J, Hagen KR, Liu DX, Huzella LM, Kumar MR, Postnikova E, Bohannon JK, Lackemeyer MG, Cooper K, Endlich-Frazier A, Sharma H, Thomasson D, Bartos C, Sayre PJ, Sims A, Dyall J, Holbrook MR, Jahrling PB, Baric RS, Johnson RF. The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis. mSphere. 2018 12 12; 3(6). PMID: 30541777.
      Citations: 2     Fields:    Translation:AnimalsCells
    12. Agostini ML, Andres EL, Sims AC, Graham RL, Sheahan TP, Lu X, Smith EC, Case JB, Feng JY, Jordan R, Ray AS, Cihlar T, Siegel D, Mackman RL, Clarke MO, Baric RS, Denison MR. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. mBio. 2018 03 06; 9(2). PMID: 29511076.
      Citations: 521     Fields:    Translation:AnimalsCells
    13. Menachery VD, Schäfer A, Burnum-Johnson KE, Mitchell HD, Eisfeld AJ, Walters KB, Nicora CD, Purvine SO, Casey CP, Monroe ME, Weitz KK, Stratton KG, Webb-Robertson BM, Gralinski LE, Metz TO, Smith RD, Waters KM, Sims AC, Kawaoka Y, Baric RS. MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E1012-E1021. PMID: 29339515.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    14. Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH, Leist SR, Yount BL, Graham RL, McAnarney ET, Stratton KG, Cockrell AS, Debbink K, Sims AC, Waters KM, Baric RS. Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis. mSphere. 2017 Nov-Dec; 2(6). PMID: 29152578.
      Citations: 45     Fields:    
    15. Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski LE, Case JB, Leist SR, Pyrc K, Feng JY, Trantcheva I, Bannister R, Park Y, Babusis D, Clarke MO, Mackman RL, Spahn JE, Palmiotti CA, Siegel D, Ray AS, Cihlar T, Jordan R, Denison MR, Baric RS. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med. 2017 06 28; 9(396). PMID: 28659436.
      Citations: 572     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Nakayasu ES, Nicora CD, Sims AC, Burnum-Johnson KE, Kim YM, Kyle JE, Matzke MM, Shukla AK, Chu RK, Schepmoes AA, Jacobs JM, Baric RS, Webb-Robertson BJ, Smith RD, Metz TO. MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses. mSystems. 2016 May-Jun; 1(3). PMID: 27822525.
      Citations: 64     
    17. Thornbrough JM, Jha BK, Yount B, Goldstein SA, Li Y, Elliott R, Sims AC, Baric RS, Silverman RH, Weiss SR. Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation. mBio. 2016 Mar 29; 7(2):e00258. PMID: 27025250.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    18. Menachery VD, Yount BL, Sims AC, Debbink K, Agnihothram SS, Gralinski LE, Graham RL, Scobey T, Plante JA, Royal SR, Swanstrom J, Sheahan TP, Pickles RJ, Corti D, Randell SH, Lanzavecchia A, Marasco WA, Baric RS. SARS-like WIV1-CoV poised for human emergence. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):3048-53. PMID: 26976607.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    19. Huang X, Dong W, Milewska A, Golda A, Qi Y, Zhu QK, Marasco WA, Baric RS, Sims AC, Pyrc K, Li W, Sui J. Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme. J Virol. 2015 Jul; 89(14):7202-13. PMID: 25926653.
      Citations: 101     Fields:    Translation:HumansCells
    20. Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, Fan S, Ferris MT, Gralinski LE, Green RR, Gritsenko MA, Hatta M, Heegel RA, Jacobs JM, Jeng S, Josset L, Kaiser SM, Kelly S, Law GL, Li C, Li J, Long C, Luna ML, Matzke M, McDermott J, Menachery V, Metz TO, Mitchell H, Monroe ME, Navarro G, Neumann G, Podyminogin RL, Purvine SO, Rosenberger CM, Sanders CJ, Schepmoes AA, Shukla AK, Sims A, Sova P, Tam VC, Tchitchek N, Thomas PG, Tilton SC, Totura A, Wang J, Webb-Robertson BJ, Wen J, Weiss JM, Yang F, Yount B, Zhang Q, McWeeney S, Smith RD, Waters KM, Kawaoka Y, Baric R, Aderem A, Katze MG, Scheuermann RH. A comprehensive collection of systems biology data characterizing the host response to viral infection. Sci Data. 2014; 1:140033. PMID: 25977790.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    21. Menachery VD, Eisfeld AJ, Schäfer A, Josset L, Sims AC, Proll S, Fan S, Li C, Neumann G, Tilton SC, Chang J, Gralinski LE, Long C, Green R, Williams CM, Weiss J, Matzke MM, Webb-Robertson BJ, Schepmoes AA, Shukla AK, Metz TO, Smith RD, Waters KM, Katze MG, Kawaoka Y, Baric RS. Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses. mBio. 2014 May 20; 5(3):e01174-14. PMID: 24846384.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    22. Scobey T, Yount BL, Sims AC, Donaldson EF, Agnihothram SS, Menachery VD, Graham RL, Swanstrom J, Bove PF, Kim JD, Grego S, Randell SH, Baric RS. Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A. 2013 Oct 01; 110(40):16157-62. PMID: 24043791.
      Citations: 149     Fields:    Translation:HumansCells
    23. Mitchell HD, Eisfeld AJ, Sims AC, McDermott JE, Matzke MM, Webb-Robertson BJ, Tilton SC, Tchitchek N, Josset L, Li C, Ellis AL, Chang JH, Heegel RA, Luna ML, Schepmoes AA, Shukla AK, Metz TO, Neumann G, Benecke AG, Smith RD, Baric RS, Kawaoka Y, Katze MG, Waters KM. A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. PLoS One. 2013; 8(7):e69374. PMID: 23935999.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    24. Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J Virol. 2013 Apr; 87(7):3885-902. PMID: 23365422.
      Citations: 64     Fields:    Translation:HumansCells
    25. Plant EP, Sims AC, Baric RS, Dinman JD, Taylor DR. Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production. Viruses. 2013 Jan 18; 5(1):279-94. PMID: 23334702.
      Citations: 27     Fields:    Translation:HumansCells
    26. Ishimaru D, Plant EP, Sims AC, Yount BL, Roth BM, Eldho NV, Pérez-Alvarado GC, Armbruster DW, Baric RS, Dinman JD, Taylor DR, Hennig M. RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus. Nucleic Acids Res. 2013 Feb 01; 41(4):2594-608. PMID: 23275571.
      Citations: 23     Fields:    Translation:Cells
    27. te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathog. 2010 Nov 04; 6(11):e1001176. PMID: 21079686.
      Citations: 244     Fields:    Translation:AnimalsCells
    28. Pyrc K, Sims AC, Dijkman R, Jebbink M, Long C, Deming D, Donaldson E, Vabret A, Baric R, van der Hoek L, Pickles R. Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures. J Virol. 2010 Nov; 84(21):11255-63. PMID: 20719951.
      Citations: 71     Fields:    Translation:HumansCells
    29. Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19944-9. PMID: 19036930.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    30. Donaldson EF, Yount B, Sims AC, Burkett S, Pickles RJ, Baric RS. Systematic assembly of a full-length infectious clone of human coronavirus NL63. J Virol. 2008 Dec; 82(23):11948-57. PMID: 18818320.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    31. Pacciarini F, Ghezzi S, Canducci F, Sims A, Sampaolo M, Ferioli E, Clementi M, Poli G, Conaldi PG, Baric R, Vicenzi E. Persistent replication of severe acute respiratory syndrome coronavirus in human tubular kidney cells selects for adaptive mutations in the membrane protein. J Virol. 2008 Jun; 82(11):5137-44. PMID: 18367528.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    32. Donaldson EF, Sims AC, Baric RS. Systematic assembly and genetic manipulation of the mouse hepatitis virus A59 genome. Methods Mol Biol. 2008; 454:293-315. PMID: 19057869.
      Citations: 2     Fields:    Translation:AnimalsCells
    33. Sheahan T, Rockx B, Donaldson E, Sims A, Pickles R, Corti D, Baric R. Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J Virol. 2008 Mar; 82(5):2274-85. PMID: 18094188.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    34. Rockx B, Sheahan T, Donaldson E, Harkema J, Sims A, Heise M, Pickles R, Cameron M, Kelvin D, Baric R. Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. J Virol. 2007 Jul; 81(14):7410-23. PMID: 17507479.
      Citations: 45     Fields:    Translation:AnimalsCells
    35. Sims AC, Burkett SE, Yount B, Pickles RJ. SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium. Virus Res. 2008 Apr; 133(1):33-44. PMID: 17451829.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    36. Donaldson EF, Graham RL, Sims AC, Denison MR, Baric RS. Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing. J Virol. 2007 Jul; 81(13):7086-98. PMID: 17428870.
      Citations: 32     Fields:    Translation:AnimalsCells
    37. Graham RL, Sparks JS, Eckerle LD, Sims AC, Denison MR. SARS coronavirus replicase proteins in pathogenesis. Virus Res. 2008 Apr; 133(1):88-100. PMID: 17397959.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    38. Donaldson EF, Sims AC, Graham RL, Denison MR, Baric RS. Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. J Virol. 2007 Jun; 81(12):6356-68. PMID: 17392363.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    39. Deming D, Sheahan T, Heise M, Yount B, Davis N, Sims A, Suthar M, Harkema J, Whitmore A, Pickles R, West A, Donaldson E, Curtis K, Johnston R, Baric R. Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 2006 Dec; 3(12):e525. PMID: 17194199.
      Citations: 141     Fields:    Translation:AnimalsCellsPHPublic Health
    40. Donaldson EF, Sims AC, Deming DJ, Baric RS. Mutational analysis of MHV-A59 replicase protein-nsp10. Adv Exp Med Biol. 2006; 581:61-6. PMID: 17037505.
      Citations: 2     Fields:    Translation:AnimalsCells
    41. Graham RL, Sims AC, Baric RS, Denison MR. The nsp2 proteins of mouse hepatitis virus and SARS coronavirus are dispensable for viral replication. Adv Exp Med Biol. 2006; 581:67-72. PMID: 17037506.
      Citations: 13     Fields:    Translation:AnimalsCells
    42. Pekosz A, Schaecher SR, Diamond MS, Fremont DH, Sims AC, Baric RS. Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Adv Exp Med Biol. 2006; 581:115-20. PMID: 17037516.
      Citations: 14     Fields:    Translation:AnimalsCells
    43. Frieman MB, Yount B, Sims AC, Deming DJ, Morrison TE, Sparks J, Denison M, Heise M, Baric RS. SARS coronavirus accessory ORFs encode luxury functions. Adv Exp Med Biol. 2006; 581:149-52. PMID: 17037522.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    44. Sims AC, Yount B, Burkett SE, Baric RS, Pickles RJ. SARS CoV replication and pathogenesis in human airway epithelial cultures. Adv Exp Med Biol. 2006; 581:535-8. PMID: 17037593.
      Citations: 8     Fields:    Translation:HumansCells
    45. Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. SARS coronavirus vaccine development. Adv Exp Med Biol. 2006; 581:553-60. PMID: 17037597.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    46. Roberts RS, Yount BL, Sims AC, Baker S, Baric RS. Renilla luciferase as a reporter to assess SARS-CoV mRNA transcription regulation and efficacy of anti-SARS-CoV agents. Adv Exp Med Biol. 2006; 581:597-600. PMID: 17037604.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    47. Yount B, Roberts RS, Sims AC, Deming D, Frieman MB, Sparks J, Denison MR, Davis N, Baric RS. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol. 2005 Dec; 79(23):14909-22. PMID: 16282490.
      Citations: 145     Fields:    Translation:AnimalsCells
    48. Sims AC, Baric RS, Yount B, Burkett SE, Collins PL, Pickles RJ. Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. J Virol. 2005 Dec; 79(24):15511-24. PMID: 16306622.
      Citations: 156     Fields:    Translation:HumansCells
    49. Graham RL, Sims AC, Brockway SM, Baric RS, Denison MR. The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. J Virol. 2005 Nov; 79(21):13399-411. PMID: 16227261.
      Citations: 91     Fields:    Translation:AnimalsCells
    50. Baric RS, Sims AC. Humanized mice develop coronavirus respiratory disease. Proc Natl Acad Sci U S A. 2005 Jun 07; 102(23):8073-4. PMID: 15928078.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    51. Baric RS, Sims AC. Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs. Curr Top Microbiol Immunol. 2005; 287:229-52. PMID: 15609514.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    52. Denison MR, Yount B, Brockway SM, Graham RL, Sims AC, Lu X, Baric RS. Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. J Virol. 2004 Jun; 78(11):5957-65. PMID: 15140993.
      Citations: 31     Fields:    Translation:Cells
    53. Curtis KM, Yount B, Sims AC, Baric RS. Reverse genetic analysis of the transcription regulatory sequence of the coronavirus transmissible gastroenteritis virus. J Virol. 2004 Jun; 78(11):6061-6. PMID: 15141005.
      Citations: 7     Fields:    Translation:Cells
    54. Denison MR, Sims AC. MHV-A59 gene 1 proteins are associated with two distinct membrane populations. Adv Exp Med Biol. 2001; 494:655-61. PMID: 11774541.
      Citations: 2     Fields:    Translation:AnimalsCells
    55. Sims AC, Ostermann J, Denison MR. Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes. J Virol. 2000 Jun; 74(12):5647-54. PMID: 10823872.
      Citations: 46     Fields:    Translation:AnimalsCells
    56. Denison MR, Spaan WJ, van der Meer Y, Gibson CA, Sims AC, Prentice E, Lu XT. The putative helicase of the coronavirus mouse hepatitis virus is processed from the replicase gene polyprotein and localizes in complexes that are active in viral RNA synthesis. J Virol. 1999 Aug; 73(8):6862-71. PMID: 10400784.
      Citations: 55     Fields:    Translation:AnimalsCells
    57. Lu XT, Sims AC, Denison MR. Mouse hepatitis virus 3C-like protease cleaves a 22-kilodalton protein from the open reading frame 1a polyprotein in virus-infected cells and in vitro. J Virol. 1998 Mar; 72(3):2265-71. PMID: 9499085.
      Citations: 35     Fields:    Translation:AnimalsCells
    58. Denison MR, Sims AC, Gibson CA, Lu XT. Processing of the MHV-A59 gene 1 polyprotein by the 3C-like proteinase. Adv Exp Med Biol. 1998; 440:121-7. PMID: 9782273.
      Citations: 9     Fields:    Translation:AnimalsCells
    59. Sims AC, Lu XT, Denison MR. Expression, purification, and activity of recombinant MHV-A59 3CLpro. Adv Exp Med Biol. 1998; 440:129-34. PMID: 9782274.
      Citations:    Fields:    Translation:AnimalsCells