Co-Authors
This is a "connection" page, showing publications co-authored by Kwok-Yung Yuen and Jasper Chan.
Connection Strength
27.227
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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility. Clin Infect Dis. 2020 12 03; 71(9):2428-2446.
Score: 0.917
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Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020 11 19; 71(16):2139-2149.
Score: 0.914
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A Case Series of Children With Coronavirus Disease 2019: What Have We Learned? Clin Infect Dis. 2020 09 12; 71(6):1552-1553.
Score: 0.902
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Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020 04 23; 58(5).
Score: 0.878
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Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect. 2020; 9(1):221-236.
Score: 0.864
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A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 02 15; 395(10223):514-523.
Score: 0.864
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The celecoxib derivative kinase inhibitor AR-12 (OSU-03012) inhibits Zika virus via down-regulation of the PI3K/Akt pathway and protects Zika virus-infected A129 mice: A host-targeting treatment strategy. Antiviral Res. 2018 12; 160:38-47.
Score: 0.790
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Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus. Trop Med Int Health. 2017 05; 22(5):594-603.
Score: 0.708
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Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor. Antiviral Res. 2017 05; 141:29-37.
Score: 0.703
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Treatment With Lopinavir/Ritonavir or Interferon-ß1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset. J Infect Dis. 2015 Dec 15; 212(12):1904-13.
Score: 0.632
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Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses. J Clin Microbiol. 2015 Aug; 53(8):2722-6.
Score: 0.625
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Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev. 2015 Apr; 28(2):465-522.
Score: 0.618
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Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect. 2013 Dec; 67(6):606-16.
Score: 0.558
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Reply to Leow. J Infect Dis. 2013 Oct 15; 208(8):1351-2.
Score: 0.550
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Interspecies transmission and emergence of novel viruses: lessons from bats and birds. Trends Microbiol. 2013 Oct; 21(10):544-55.
Score: 0.546
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Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis. 2013 Jun 01; 207(11):1743-52.
Score: 0.538
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Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? J Infect. 2012 Dec; 65(6):477-89.
Score: 0.521
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Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic. Emerg Microbes Infect. 2021 Dec; 10(1):507-535.
Score: 0.245
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Intravenous injection of COVID-19 mRNA vaccine can induce acute myopericarditis in mouse model. Clin Infect Dis. 2021 Aug 18.
Score: 0.241
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Absence of Vaccine-enhanced Disease With Unexpected Positive Protection Against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Inactivated Vaccine Given Within 3 Days of Virus Challenge in Syrian Hamster Model. Clin Infect Dis. 2021 08 02; 73(3):e719-e734.
Score: 0.240
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Severe Acute Respiratory Syndrome Coronavirus 2 Infects and Damages the Mature and Immature Olfactory Sensory Neurons of Hamsters. Clin Infect Dis. 2021 07 15; 73(2):e503-e512.
Score: 0.239
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Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. Sci Adv. 2021 06; 7(25).
Score: 0.238
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Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters. Clin Infect Dis. 2021 06 15; 72(12):e978-e992.
Score: 0.238
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In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor. Int J Biol Sci. 2021; 17(6):1555-1564.
Score: 0.235
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Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature. 2021 05; 593(7859):418-423.
Score: 0.234
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Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2. Nat Commun. 2021 03 09; 12(1):1517.
Score: 0.233
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Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 04 15; 184(8):2212-2228.e12.
Score: 0.233
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Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021 01 08; 12(1):134.
Score: 0.231
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Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target. Emerg Microbes Infect. 2020 Dec; 9(1):2663-2672.
Score: 0.229
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Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein. mBio. 2020 10 20; 11(5).
Score: 0.227
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SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19. Cell Mol Gastroenterol Hepatol. 2021; 11(3):771-781.
Score: 0.226
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Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters. Cell Rep Med. 2020 10 20; 1(7):100121.
Score: 0.226
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Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. Infection. 2021 Apr; 49(2):257-265.
Score: 0.226
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Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19. Clin Infect Dis. 2020 09 12; 71(6):1400-1409.
Score: 0.226
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Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target. Sci Adv. 2020 08; 6(35):eaba7910.
Score: 0.225
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Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation. J Infect Dis. 2020 08 04; 222(5):734-745.
Score: 0.224
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Consistent Detection of 2019 Novel Coronavirus in Saliva. Clin Infect Dis. 2020 07 28; 71(15):841-843.
Score: 0.224
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Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong. J Clin Microbiol. 2020 Jul 23; 58(8).
Score: 0.223
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Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-ß and IFN inducer. J Infect. 2020 10; 81(4):e1-e10.
Score: 0.223
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Factors affecting stability and infectivity of SARS-CoV-2. J Hosp Infect. 2020 Oct; 106(2):226-231.
Score: 0.223
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SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series. Lancet Infect Dis. 2020 09; 20(9):1051-1060.
Score: 0.222
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Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020 06 10; 12(6).
Score: 0.222
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Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2020 11; 41(11):1258-1265.
Score: 0.222
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Early-Morning vs Spot Posterior Oropharyngeal Saliva for Diagnosis of SARS-CoV-2 Infection: Implication of Timing of Specimen Collection for Community-Wide Screening. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa210.
Score: 0.221
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Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study. Lancet Microbe. 2020 Jul; 1(3):e111-e118.
Score: 0.221
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Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system. Pharmacol Res. 2020 09; 159:104960.
Score: 0.221
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Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection. J Clin Virol. 2020 08; 129:104476.
Score: 0.221
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Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the prepandemic phase in Hong Kong. Am J Infect Control. 2020 08; 48(8):890-896.
Score: 0.221
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Infection of bat and human intestinal organoids by SARS-CoV-2. Nat Med. 2020 07; 26(7):1077-1083.
Score: 0.220
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Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet. 2020 05 30; 395(10238):1695-1704.
Score: 0.220
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The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2. J Infect. 2020 07; 81(1):107-114.
Score: 0.220
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Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020 May; 1(1):e14-e23.
Score: 0.220
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Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens. Int J Mol Sci. 2020 Apr 08; 21(7).
Score: 0.219
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Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020 05; 20(5):565-574.
Score: 0.218
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Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong. Infect Control Hosp Epidemiol. 2020 05; 41(5):493-498.
Score: 0.218
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Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages. J Infect Dis. 2020 02 03; 221(4):647-659.
Score: 0.216
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Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China. Viruses. 2019 10 24; 11(11).
Score: 0.212
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Nosocomial transmission of chickenpox and varicella zoster virus seroprevalence rate amongst healthcare workers in a teaching hospital in China. BMC Infect Dis. 2019 Jul 05; 19(1):582.
Score: 0.208
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Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay. J Clin Pathol. 2019 Jul; 72(7):487-492.
Score: 0.204
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Targeting SUMO Modification of the Non-Structural Protein 5 of Zika Virus as a Host-Targeting Antiviral Strategy. Int J Mol Sci. 2019 Jan 17; 20(2).
Score: 0.201
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Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication. Viruses. 2019 01 16; 11(1).
Score: 0.201
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SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun. 2019 01 10; 10(1):120.
Score: 0.201
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Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant. Emerg Infect Dis. 2018 12; 24(12):2241-2250.
Score: 0.199
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Human tryptophanyl-tRNA synthetase is an IFN-?-inducible entry factor for Enterovirus. J Clin Invest. 2018 11 01; 128(11):5163-5177.
Score: 0.198
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Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus. Virol J. 2018 09 27; 15(1):149.
Score: 0.197
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Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018 07 27; 293(30):11709-11726.
Score: 0.193
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Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China. Emerg Infect Dis. 2018 01; 24(1).
Score: 0.188
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Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping. Diagn Microbiol Infect Dis. 2018 May; 91(1):34-37.
Score: 0.187
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Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus. Sci Adv. 2017 11; 3(11):eaao4966.
Score: 0.185
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Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo. Antiviral Res. 2017 Sep; 145:33-43.
Score: 0.181
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Unexpectedly Higher Morbidity and Mortality of Hospitalized Elderly Patients Associated with Rhinovirus Compared with Influenza Virus Respiratory Tract Infection. Int J Mol Sci. 2017 Jan 26; 18(2).
Score: 0.175
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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome Coronavirus. J Virol. 2016 10 15; 90(20):9114-27.
Score: 0.172
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Clinical Evaluation of the New High-Throughput Luminex NxTAG Respiratory Pathogen Panel Assay for Multiplex Respiratory Pathogen Detection. J Clin Microbiol. 2016 07; 54(7):1820-1825.
Score: 0.167
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MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2. Nat Microbiol. 2016 Feb 22; 1:16004.
Score: 0.165
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Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 05; 15(5):327-47.
Score: 0.164
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Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis. Virol J. 2015 Dec 22; 12:218.
Score: 0.163
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Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways. J Infect Dis. 2016 Mar 15; 213(6):904-14.
Score: 0.158
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Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology. 2014 Apr; 454-455:197-205.
Score: 0.144
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Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment. J Gen Virol. 2013 Dec; 94(Pt 12):2679-2690.
Score: 0.139
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Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis. 2014 May 01; 209(9):1331-42.
Score: 0.139
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Clinical management and infection control of SARS: lessons learned. Antiviral Res. 2013 Nov; 100(2):407-19.
Score: 0.138
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From SARS coronavirus to novel animal and human coronaviruses. J Thorac Dis. 2013 Aug; 5 Suppl 2:S103-8.
Score: 0.138
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Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests. J Infect. 2013 Aug; 67(2):130-40.
Score: 0.135
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Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection. Emerg Microbes Infect. 2021 Dec; 10(1):291-304.
Score: 0.061
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A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters. Emerg Microbes Infect. 2021 Dec; 10(1):874-884.
Score: 0.061
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Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients. Clin Infect Dis. 2021 07 15; 73(2):e437-e444.
Score: 0.060
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Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun. 2021 07 09; 12(1):4210.
Score: 0.060
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Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein. Nat Commun. 2021 05 13; 12(1):2790.
Score: 0.059
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Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Cell Host Microbe. 2021 04 14; 29(4):551-563.e5.
Score: 0.058
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SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Emerg Microbes Infect. 2020 Dec; 9(1):1418-1428.
Score: 0.057
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Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec; 9(1):837-842.
Score: 0.057
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Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2. Emerg Microbes Infect. 2020 Dec; 9(1):1356-1359.
Score: 0.057
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Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nat Microbiol. 2020 11; 5(11):1439-1448.
Score: 0.057
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Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay. Int J Mol Sci. 2020 Sep 09; 21(18).
Score: 0.056
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Absence of nosocomial influenza and respiratory syncytial virus infection in the coronavirus disease 2019 (COVID-19) era: Implication of universal masking in hospitals. Infect Control Hosp Epidemiol. 2021 Feb; 42(2):218-221.
Score: 0.056
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Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. Int J Mol Sci. 2020 Aug 07; 21(16).
Score: 0.056
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SARS-CoV-2 infects human neural progenitor cells and brain organoids. Cell Res. 2020 10; 30(10):928-931.
Score: 0.056
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature. 2020 10; 586(7827):113-119.
Score: 0.056
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Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature. 2020 08; 584(7821):450-456.
Score: 0.056
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Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits. J Clin Virol. 2020 08; 129:104519.
Score: 0.056
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Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing. J Med Virol. 2020 11; 92(11):2725-2734.
Score: 0.055
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Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins. Emerg Microbes Infect. 2018 Dec 10; 7(1):209.
Score: 0.050
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Emergence of Cytomegalovirus Mononucleosis Syndrome Among Young Adults in Hong Kong Linked to Falling Seroprevalence: Results of a 14-Year Seroepidemiological Study. Open Forum Infect Dis. 2018 Oct; 5(10):ofy262.
Score: 0.049
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Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models. J Infect Dis. 2018 07 02; 218(3):365-377.
Score: 0.048
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Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding. J Infect Dis. 2018 06 20; 218(2):197-207.
Score: 0.048
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Fatal pancytopenia due to albendazole treatment for strongyloidiasis. IDCases. 2018; 12:112-116.
Score: 0.048
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Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein. J Virol. 2017 07 15; 91(14).
Score: 0.045
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First Report of a Fatal Case Associated with EV-D68 Infection in Hong Kong and Emergence of an Interclade Recombinant in China Revealed by Genome Analysis. Int J Mol Sci. 2017 May 16; 18(5).
Score: 0.045
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Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination. J Virol. 2015 Oct; 89(20):10532-47.
Score: 0.040
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A sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirus. Emerg Microbes Infect. 2015 Apr; 4(4):e26.
Score: 0.039
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Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun. 2014; 5:3067.
Score: 0.035
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Clinical spectrum of exophiala infections and a novel Exophiala species, Exophiala hongkongensis. J Clin Microbiol. 2013 Jan; 51(1):260-7.
Score: 0.033