Johan Neyts

InstitutionUniversity of Leuven
AddressBelgium
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 32 Covid-19 publications, with a maximum of 6 publications in July 2021
    All Publications
    Bar chart showing 453 publications over 28 distinct years, with a maximum of 40 publications in 2016
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Abdelnabi R, Foo CS, De Jonghe S, Maes P, Weynand B, Neyts J. Molnupiravir Inhibits Replication of the Emerging SARS-CoV-2 Variants of Concern in a Hamster Infection Model. J Infect Dis. 2021 09 01; 224(5):749-753. PMID: 34244768.
      Citations: 4     Fields:    Translation:HumansAnimalsPHPublic HealthCTClinical Trials
    2. Citations: 17     Fields:    Translation:HumansAnimalsCells
    3. Kasprzyk R, Spiewla TJ, Smietanski M, Golojuch S, Vangeel L, De Jonghe S, Jochmans D, Neyts J, Kowalska J, Jemielity J. Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase. Antiviral Res. 2021 09; 193:105142. PMID: 34303749.
      Citations: 1     Fields:    Translation:HumansCells
    4. Citations: 24     Fields:    Translation:HumansAnimals
    5. Citations: 29     Fields:    Translation:HumansAnimalsCells
    6. Citations: 10     Fields:    Translation:HumansCells
    7. Persoons L, Vanderlinden E, Vangeel L, Wang X, Do NDT, Foo SC, Leyssen P, Neyts J, Jochmans D, Schols D, De Jonghe S. Broad spectrum anti-coronavirus activity of a series of anti-malaria quinoline analogues. Antiviral Res. 2021 09; 193:105127. PMID: 34217752.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    8. Van Damme E, De Meyer S, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Jochmans D, Leyssen P, Buyck C, Neyts J, Van Loock M. In vitro activity of itraconazole against SARS-CoV-2. J Med Virol. 2021 Jul; 93(7):4454-4460. PMID: 33666253.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Do TND, Donckers K, Vangeel L, Chatterjee AK, Gallay PA, Bobardt MD, Bilello JP, Cihlar T, De Jonghe S, Neyts J, Jochmans D. A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents. Antiviral Res. 2021 08; 192:105122. PMID: 34186107.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    10. Citations:    Fields:    
    11. Dallmeier K, Meyfroidt G, Neyts J. COVID-19 and the intensive care unit: vaccines to the rescue. Intensive Care Med. 2021 07; 47(7):786-789. PMID: 34031699.
      Citations: 1     Fields:    Translation:Humans
    12. Abdelnabi R, Boudewijns R, Foo CS, Seldeslachts L, Sanchez-Felipe L, Zhang X, Delang L, Maes P, Kaptein SJF, Weynand B, Vande Velde G, Neyts J, Dallmeier K. Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters. EBioMedicine. 2021 Jun; 68:103403. PMID: 34049240.
      Citations: 14     Fields:    Translation:Animals
    13. Pismataro MC, Felicetti T, Bertagnin C, Nizi MG, Bonomini A, Barreca ML, Cecchetti V, Jochmans D, De Jonghe S, Neyts J, Loregian A, Tabarrini O, Massari S. 1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors. Eur J Med Chem. 2021 Oct 05; 221:113494. PMID: 33962311.
      Citations:    Fields:    Translation:HumansAnimalsCells
    14. Dai W, Jochmans D, Xie H, Yang H, Li J, Su H, Chang D, Wang J, Peng J, Zhu L, Nian Y, Hilgenfeld R, Jiang H, Chen K, Zhang L, Xu Y, Neyts J, Liu H. Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2. J Med Chem. 2022 02 24; 65(4):2794-2808. PMID: 33872498.
      Citations: 2     Fields:    
    15. Vandyck K, Abdelnabi R, Gupta K, Jochmans D, Jekle A, Deval J, Misner D, Bardiot D, Foo CS, Liu C, Ren S, Beigelman L, Blatt LM, Boland S, Vangeel L, Dejonghe S, Chaltin P, Marchand A, Serebryany V, Stoycheva A, Chanda S, Symons JA, Raboisson P, Neyts J. ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model. Biochem Biophys Res Commun. 2021 05 28; 555:134-139. PMID: 33813272.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    16. Citations: 2     Fields:    Translation:HumansAnimalsCells
    17. McCallum M, De Marco A, Lempp FA, Tortorici MA, Pinto D, Walls AC, Beltramello M, Chen A, Liu Z, Zatta F, Zepeda S, di Iulio J, Bowen JE, Montiel-Ruiz M, Zhou J, Rosen LE, Bianchi S, Guarino B, Fregni CS, Abdelnabi R, Foo SC, Rothlauf PW, Bloyet LM, Benigni F, Cameroni E, Neyts J, Riva A, Snell G, Telenti A, Whelan SPJ, Virgin HW, Corti D, Pizzuto MS, Veesler D. N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2. Cell. 2021 04 29; 184(9):2332-2347.e16. PMID: 33761326.
      Citations: 151     Fields:    Translation:AnimalsCells
    18. Baggen J, Persoons L, Vanstreels E, Jansen S, Van Looveren D, Boeckx B, Geudens V, De Man J, Jochmans D, Wauters J, Wauters E, Vanaudenaerde BM, Lambrechts D, Neyts J, Dallmeier K, Thibaut HJ, Jacquemyn M, Maes P, Daelemans D. Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2. Nat Genet. 2021 04; 53(4):435-444. PMID: 33686287.
      Citations: 19     Fields:    Translation:HumansCellsPHPublic Health
    19. Gangadevi S, Badavath VN, Thakur A, Yin N, De Jonghe S, Acevedo O, Jochmans D, Leyssen P, Wang K, Neyts J, Yujie T, Blum G. Kobophenol A Inhibits Binding of Host ACE2 Receptor with Spike RBD Domain of SARS-CoV-2, a Lead Compound for Blocking COVID-19. J Phys Chem Lett. 2021 Feb 25; 12(7):1793-1802. PMID: 33577324.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    20. Wauters E, Van Mol P, Garg AD, Jansen S, Van Herck Y, Vanderbeke L, Bassez A, Boeckx B, Malengier-Devlies B, Timmerman A, Van Brussel T, Van Buyten T, Schepers R, Heylen E, Dauwe D, Dooms C, Gunst J, Hermans G, Meersseman P, Testelmans D, Yserbyt J, Tejpar S, De Wever W, Matthys P, Neyts J, Wauters J, Qian J, Lambrechts D. Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages. Cell Res. 2021 03; 31(3):272-290. PMID: 33473155.
      Citations: 44     Fields:    Translation:HumansCells
    21. Citations: 42     Fields:    Translation:AnimalsCells
    22. Citations: 55     Fields:    Translation:AnimalsCellsPHPublic Health
    23. Rut W, Groborz K, Zhang L, Sun X, Zmudzinski M, Pawlik B, Wang X, Jochmans D, Neyts J, Mlynarski W, Hilgenfeld R, Drag M. SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging. Nat Chem Biol. 2021 02; 17(2):222-228. PMID: 33093684.
      Citations: 36     Fields:    Translation:HumansCells
    24. Kaptein SJF, Jacobs S, Langendries L, Seldeslachts L, Ter Horst S, Liesenborghs L, Hens B, Vergote V, Heylen E, Barthelemy K, Maas E, De Keyzer C, Bervoets L, Rymenants J, Van Buyten T, Zhang X, Abdelnabi R, Pang J, Williams R, Thibaut HJ, Dallmeier K, Boudewijns R, Wouters J, Augustijns P, Verougstraete N, Cawthorne C, Breuer J, Solas C, Weynand B, Annaert P, Spriet I, Vande Velde G, Neyts J, Rocha-Pereira J, Delang L. Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26955-26965. PMID: 33037151.
      Citations: 57     Fields:    Translation:AnimalsCells
    25. Citations: 134     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, Segalés J, Vasan SS, et al. Animal models for COVID-19. Nature. 2020 10; 586(7830):509-515. PMID: 32967005.
      Citations: 181     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    27. Gurard-Levin ZA, Liu C, Jekle A, Jaisinghani R, Ren S, Vandyck K, Jochmans D, Leyssen P, Neyts J, Blatt LM, Beigelman L, Symons JA, Raboisson P, Scholle MD, Deval J. Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry. Antiviral Res. 2020 10; 182:104924. PMID: 32896566.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    28. Funnell SGP, Dowling WE, Muñoz-Fontela C, Gsell PS, Ingber DE, Hamilton GA, Delang L, Rocha-Pereira J, Kaptein S, Dallmeier KH, Neyts J, Rosenke K, de Wit E, Feldmann H, Maisonnasse P, Le Grand R, Le Grand R, Frieman MB, Coleman CM. Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients. Nat Commun. 2020 08 26; 11(1):4253. PMID: 32848158.
      Citations: 21     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    29. Wauters E, Thevissen K, Wouters C, Bosisio FM, De Smet F, Gunst J, Humblet-Baron S, Lambrechts D, Liston A, Matthys P, Neyts J, Proost P, Weynand B, Wauters J, Tejpar S, Garg AD. Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology. Front Immunol. 2020; 11:1642. PMID: 32719686.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    30. Torneri A, Libin P, Vanderlocht J, Vandamme AM, Neyts J, Hens N. A prospect on the use of antiviral drugs to control local outbreaks of COVID-19. BMC Med. 2020 06 25; 18(1):191. PMID: 32586336.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    31. Delang L, Neyts J. Medical treatment options for COVID-19. Eur Heart J Acute Cardiovasc Care. 2020 Apr; 9(3):209-214. PMID: 32363880.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    32. Zhang L, Lin D, Kusov Y, Nian Y, Ma Q, Wang J, von Brunn A, Leyssen P, Lanko K, Neyts J, de Wilde A, Snijder EJ, Liu H, Hilgenfeld R. a-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment. J Med Chem. 2020 05 14; 63(9):4562-4578. PMID: 32045235.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    33. Li C, Debing Y, Jankevicius G, Neyts J, Ahel I, Coutard B, Canard B. Viral Macro Domains Reverse Protein ADP-Ribosylation. J Virol. 2016 10 01; 90(19):8478-86. PMID: 27440879.
      Citations: 66     Fields:    Translation:HumansCells
    34. Peters HL, Jochmans D, de Wilde AH, Posthuma CC, Snijder EJ, Neyts J, Seley-Radtke KL. Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. Bioorg Med Chem Lett. 2015 Aug 01; 25(15):2923-6. PMID: 26048809.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    35. de Wilde AH, Jochmans D, Posthuma CC, Zevenhoven-Dobbe JC, van Nieuwkoop S, Bestebroer TM, van den Hoogen BG, Neyts J, Snijder EJ. Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob Agents Chemother. 2014 Aug; 58(8):4875-84. PMID: 24841269.
      Citations: 304     Fields:    Translation:HumansAnimalsCells
    36. Jochmans D, Leyssen P, Neyts J. A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE. J Virol Methods. 2012 Aug; 183(2):176-9. PMID: 22575574.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    37. Obeid S, Printsevskaya SS, Olsufyeva EN, Dallmeier K, Durantel D, Zoulim F, Preobrazhenskaya MN, Neyts J, Paeshuyse J. Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics. J Antimicrob Chemother. 2011 Jun; 66(6):1287-94. PMID: 21436155.
      Citations: 11     Fields:    Translation:HumansCells
    38. Keyaerts E, Vijgen L, Maes P, Duson G, Neyts J, Van Ranst M. Viral load quantitation of SARS-coronavirus RNA using a one-step real-time RT-PCR. Int J Infect Dis. 2006 Jan; 10(1):32-7. PMID: 16023880.
      Citations: 12     Fields:    Translation:AnimalsCells
    39. Keyaerts E, Vijgen L, Maes P, Neyts J, Van Ranst M. Growth kinetics of SARS-coronavirus in Vero E6 cells. Biochem Biophys Res Commun. 2005 Apr 15; 329(3):1147-51. PMID: 15752773.
      Citations: 11     Fields:    Translation:AnimalsCells
    40. Keyaerts E, Vijgen L, Maes P, Neyts J, Van Ranst M. In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine. Biochem Biophys Res Commun. 2004 Oct 08; 323(1):264-8. PMID: 15351731.
      Citations: 269     Fields:    Translation:HumansAnimalsCells
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