Connection

Co-Authors

This is a "connection" page, showing publications co-authored by Jasper Chan and Kelvin To.
Connection Strength

6.964
  1. Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic. Emerg Microbes Infect. 2021 Dec; 10(1):507-535.
    View in: PubMed
    Score: 0.245
  2. Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility. Clin Infect Dis. 2020 12 03; 71(9):2428-2446.
    View in: PubMed
    Score: 0.229
  3. Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2. Emerg Microbes Infect. 2020 Dec; 9(1):1356-1359.
    View in: PubMed
    Score: 0.229
  4. Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020 11 19; 71(16):2139-2149.
    View in: PubMed
    Score: 0.229
  5. A Case Series of Children With Coronavirus Disease 2019: What Have We Learned? Clin Infect Dis. 2020 09 12; 71(6):1552-1553.
    View in: PubMed
    Score: 0.226
  6. Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay. Int J Mol Sci. 2020 Sep 09; 21(18).
    View in: PubMed
    Score: 0.225
  7. Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. Int J Mol Sci. 2020 Aug 07; 21(16).
    View in: PubMed
    Score: 0.224
  8. Consistent Detection of 2019 Novel Coronavirus in Saliva. Clin Infect Dis. 2020 07 28; 71(15):841-843.
    View in: PubMed
    Score: 0.224
  9. Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits. J Clin Virol. 2020 08; 129:104519.
    View in: PubMed
    Score: 0.222
  10. Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing. J Med Virol. 2020 11; 92(11):2725-2734.
    View in: PubMed
    Score: 0.222
  11. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020 06 10; 12(6).
    View in: PubMed
    Score: 0.222
  12. Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study. Lancet Microbe. 2020 Jul; 1(3):e111-e118.
    View in: PubMed
    Score: 0.221
  13. Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection. J Clin Virol. 2020 08; 129:104476.
    View in: PubMed
    Score: 0.221
  14. Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020 04 23; 58(5).
    View in: PubMed
    Score: 0.220
  15. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020 05; 20(5):565-574.
    View in: PubMed
    Score: 0.218
  16. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect. 2020; 9(1):221-236.
    View in: PubMed
    Score: 0.216
  17. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 02 15; 395(10223):514-523.
    View in: PubMed
    Score: 0.216
  18. Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses. J Clin Microbiol. 2015 Aug; 53(8):2722-6.
    View in: PubMed
    Score: 0.156
  19. Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev. 2015 Apr; 28(2):465-522.
    View in: PubMed
    Score: 0.155
  20. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect. 2013 Dec; 67(6):606-16.
    View in: PubMed
    Score: 0.139
  21. From SARS coronavirus to novel animal and human coronaviruses. J Thorac Dis. 2013 Aug; 5 Suppl 2:S103-8.
    View in: PubMed
    Score: 0.138
  22. Interspecies transmission and emergence of novel viruses: lessons from bats and birds. Trends Microbiol. 2013 Oct; 21(10):544-55.
    View in: PubMed
    Score: 0.137
  23. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis. 2013 Jun 01; 207(11):1743-52.
    View in: PubMed
    Score: 0.134
  24. Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? J Infect. 2012 Dec; 65(6):477-89.
    View in: PubMed
    Score: 0.130
  25. A novel linker-immunodominant site (LIS) vaccine targeting the SARS-CoV-2 spike protein protects against severe COVID-19 in Syrian hamsters. Emerg Microbes Infect. 2021 Dec; 10(1):874-884.
    View in: PubMed
    Score: 0.061
  26. Intravenous injection of COVID-19 mRNA vaccine can induce acute myopericarditis in mouse model. Clin Infect Dis. 2021 Aug 18.
    View in: PubMed
    Score: 0.060
  27. Absence of Vaccine-enhanced Disease With Unexpected Positive Protection Against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Inactivated Vaccine Given Within 3 Days of Virus Challenge in Syrian Hamster Model. Clin Infect Dis. 2021 08 02; 73(3):e719-e734.
    View in: PubMed
    Score: 0.060
  28. Coinfection by Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza A(H1N1)pdm09 Virus Enhances the Severity of Pneumonia in Golden Syrian Hamsters. Clin Infect Dis. 2021 06 15; 72(12):e978-e992.
    View in: PubMed
    Score: 0.059
  29. Comparative evaluation of a dual-target real-time RT-PCR assay for COVID-19 diagnosis and assessment of performance in pooled saliva and nasopharyngeal swab samples. Expert Rev Mol Diagn. 2021 07; 21(7):741-747.
    View in: PubMed
    Score: 0.059
  30. Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein. Nat Commun. 2021 05 13; 12(1):2790.
    View in: PubMed
    Score: 0.059
  31. Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2. Nat Commun. 2021 03 09; 12(1):1517.
    View in: PubMed
    Score: 0.058
  32. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 04 15; 184(8):2212-2228.e12.
    View in: PubMed
    Score: 0.058
  33. Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Cell Host Microbe. 2021 04 14; 29(4):551-563.e5.
    View in: PubMed
    Score: 0.058
  34. Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021 01 08; 12(1):134.
    View in: PubMed
    Score: 0.058
  35. SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Emerg Microbes Infect. 2020 Dec; 9(1):1418-1428.
    View in: PubMed
    Score: 0.057
  36. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec; 9(1):837-842.
    View in: PubMed
    Score: 0.057
  37. Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein. mBio. 2020 10 20; 11(5).
    View in: PubMed
    Score: 0.057
  38. SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19. Cell Mol Gastroenterol Hepatol. 2021; 11(3):771-781.
    View in: PubMed
    Score: 0.057
  39. Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters. Cell Rep Med. 2020 10 20; 1(7):100121.
    View in: PubMed
    Score: 0.057
  40. Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. Infection. 2021 Apr; 49(2):257-265.
    View in: PubMed
    Score: 0.056
  41. Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19. Clin Infect Dis. 2020 09 12; 71(6):1400-1409.
    View in: PubMed
    Score: 0.056
  42. Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target. Sci Adv. 2020 08; 6(35):eaba7910.
    View in: PubMed
    Score: 0.056
  43. Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong. J Clin Microbiol. 2020 Jul 23; 58(8).
    View in: PubMed
    Score: 0.056
  44. Factors affecting stability and infectivity of SARS-CoV-2. J Hosp Infect. 2020 Oct; 106(2):226-231.
    View in: PubMed
    Score: 0.056
  45. SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series. Lancet Infect Dis. 2020 09; 20(9):1051-1060.
    View in: PubMed
    Score: 0.055
  46. Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2020 11; 41(11):1258-1265.
    View in: PubMed
    Score: 0.055
  47. Early-Morning vs Spot Posterior Oropharyngeal Saliva for Diagnosis of SARS-CoV-2 Infection: Implication of Timing of Specimen Collection for Community-Wide Screening. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa210.
    View in: PubMed
    Score: 0.055
  48. Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the prepandemic phase in Hong Kong. Am J Infect Control. 2020 08; 48(8):890-896.
    View in: PubMed
    Score: 0.055
  49. Infection of bat and human intestinal organoids by SARS-CoV-2. Nat Med. 2020 07; 26(7):1077-1083.
    View in: PubMed
    Score: 0.055
  50. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet. 2020 05 30; 395(10238):1695-1704.
    View in: PubMed
    Score: 0.055
  51. The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2. J Infect. 2020 07; 81(1):107-114.
    View in: PubMed
    Score: 0.055
  52. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020 May; 1(1):e14-e23.
    View in: PubMed
    Score: 0.055
  53. Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens. Int J Mol Sci. 2020 Apr 08; 21(7).
    View in: PubMed
    Score: 0.055
  54. Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages. J Infect Dis. 2020 02 03; 221(4):647-659.
    View in: PubMed
    Score: 0.054
  55. Improving the specific diagnosis of trematode, cestode and nematode infections by a multiplex single-tube real-time PCR assay. J Clin Pathol. 2019 Jul; 72(7):487-492.
    View in: PubMed
    Score: 0.051
  56. SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun. 2019 01 10; 10(1):120.
    View in: PubMed
    Score: 0.050
  57. Impact of inter-genotypic recombination and probe cross-reactivity on the performance of the Abbott RealTime HCV Genotype II assay for hepatitis C genotyping. Diagn Microbiol Infect Dis. 2018 May; 91(1):34-37.
    View in: PubMed
    Score: 0.047
  58. Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus. Sci Adv. 2017 11; 3(11):eaao4966.
    View in: PubMed
    Score: 0.046
  59. Unexpectedly Higher Morbidity and Mortality of Hospitalized Elderly Patients Associated with Rhinovirus Compared with Influenza Virus Respiratory Tract Infection. Int J Mol Sci. 2017 Jan 26; 18(2).
    View in: PubMed
    Score: 0.044
  60. MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2. Nat Microbiol. 2016 Feb 22; 1:16004.
    View in: PubMed
    Score: 0.041
  61. Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways. J Infect Dis. 2016 Mar 15; 213(6):904-14.
    View in: PubMed
    Score: 0.039
  62. Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology. 2014 Apr; 454-455:197-205.
    View in: PubMed
    Score: 0.036
  63. Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis. 2014 May 01; 209(9):1331-42.
    View in: PubMed
    Score: 0.035
  64. Clinical management and infection control of SARS: lessons learned. Antiviral Res. 2013 Nov; 100(2):407-19.
    View in: PubMed
    Score: 0.035
  65. Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests. J Infect. 2013 Aug; 67(2):130-40.
    View in: PubMed
    Score: 0.034
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.