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John Ziebuhr
Institution
Justus Liebig University Giessen
Address
Giessen
Germany
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Publication Timeline
COVID-19 publications
All Publications
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To see the data from both graphs as text,
click here
.
Year
Publications
1995
1
1996
2
1997
4
1998
1
1999
1
2000
3
2001
2
2002
3
2003
6
2004
5
2005
6
2006
9
2007
1
2009
1
2010
1
2011
3
2012
2
2013
5
2014
4
2015
4
2016
8
2017
5
2018
5
2019
3
2020
3
2021
7
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To return to the graphs,
click here
.
Publication Field Summary
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
Publication List
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Show:
All coronarirus related publications
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Covid-19 specific publications
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Newest
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Most Discussed
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Konings F
,
Perkins MD
,
Kuhn JH
,
Pallen MJ
,
Alm EJ
,
Archer BN
,
Barakat A
,
Bedford T
,
Bhiman JN
,
Caly L
,
Carter LL
,
Cullinane A
,
de Oliveira T
,
Druce J
,
El Masry I
,
Evans R
,
Gao GF
,
Gorbalenya AE
,
Hamblion E
,
Herring BL
,
Hodcroft E
,
Holmes EC
,
Kakkar M
,
Khare S
,
Koopmans MPG
,
Korber B
,
Leite J
,
MacCannell D
,
Marklewitz M
,
Maurer-Stroh S
,
Rico JAM
,
Munster VJ
,
Neher R
, Munnink BO,
Pavlin BI
,
Peiris M
,
Poon L
,
Pybus O
,
Rambaut A
,
Resende P
,
Subissi L
,
Thiel V
,
Tong S
,
van der Werf S
,
von Gottberg A
,
Ziebuhr J
,
Van Kerkhove MD
. SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse. Nat Microbiol. 2021 07; 6(7):821-823.
PMID:
34108654
.
Citations:
24
Fields:
Mic
Microbiology
Par
Parasitology
Vir
Virology
Translation:
Humans
Stukalov A
,
Girault V
,
Grass V
,
Karayel O
,
Bergant V
,
Urban C
,
Haas DA
,
Huang Y
,
Oubraham L
,
Wang A
,
Hamad MS
,
Piras A
,
Hansen FM
,
Tanzer MC
,
Paron I
,
Zinzula L
,
Engleitner T
,
Reinecke M
,
Lavacca TM
,
Ehmann R
,
Wölfel R
,
Jores J
,
Kuster B
,
Protzer U
,
Rad R
,
Ziebuhr J
,
Thiel V
,
Scaturro P
,
Mann M
,
Pichlmair A
. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature. 2021 06; 594(7862):246-252.
PMID:
33845483
.
Citations:
78
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Jungreis I
,
Nelson CW
,
Ardern Z
,
Finkel Y
,
Krogan NJ
,
Sato K
,
Ziebuhr J
,
Stern-Ginossar N
,
Pavesi A
,
Firth AE
,
Gorbalenya AE
,
Kellis M
. Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution. Virology. 2021 06; 558:145-151.
PMID:
33774510
.
Citations:
5
Fields:
Vir
Virology
Taroncher-Oldenburg G
,
Müller C
,
Obermann W
,
Ziebuhr J
,
Hartmann RK
,
Grünweller A
. Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates-A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics. Microorganisms. 2021 Mar 05; 9(3).
PMID:
33807988
.
Citations:
3
Krichel B
,
Bylapudi G
,
Schmidt C
,
Blanchet C
,
Schubert R
,
Brings L
,
Koehler M
,
Zenobi R
,
Svergun D
,
Lorenzen K
,
Madhugiri R
,
Ziebuhr J
,
Uetrecht C
. Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes. Sci Adv. 2021 03; 7(10).
PMID:
33658206
.
Citations:
4
Fields:
Sci
Science
Translation:
Cells
Slanina H
,
Madhugiri R
,
Bylapudi G
,
Schultheiß K
,
Karl N
,
Gulyaeva A
,
Gorbalenya AE
,
Linne U
,
Ziebuhr J
. Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit. Proc Natl Acad Sci U S A. 2021 02 09; 118(6).
PMID:
33472860
.
Citations:
16
Fields:
Sci
Science
Translation:
Humans
Cells
Müller C
,
Obermann W
,
Karl N
,
Wendel HG
,
Taroncher-Oldenburg G
,
Pleschka S
,
Hartmann RK
,
Grünweller A
,
Ziebuhr J
. The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo. Antiviral Res. 2021 02; 186:105012.
PMID:
33422611
.
Citations:
5
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
Animals
Cells
Husain-Syed F
,
Vadász I
,
Wilhelm J
,
Walmrath HD
,
Seeger W
,
Birk HW
,
Jennert B
,
Dietrich H
,
Herold S
,
Trauth J
,
Tello K
,
Sander M
,
Morty RE
,
Slanina H
,
Schüttler CG
,
Ziebuhr J
,
Kassoumeh S
,
Ronco C
,
Ferrari F
,
Warnatz K
,
Stahl K
,
Seeliger B
,
Hoeper MM
,
Welte T
,
David S
. Immunoglobulin deficiency as an indicator of disease severity in patients with COVID-19. Am J Physiol Lung Cell Mol Physiol. 2021 04 01; 320(4):L590-L599.
PMID:
33237794
.
Citations:
3
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Phy
Physiology
Pul
Pulmonary Medicine
Translation:
Humans
Welker A
,
Kersten C
,
Müller C
,
Madhugiri R
,
Zimmer C
,
Müller P
,
Zimmermann R
,
Hammerschmidt S
,
Maus H
,
Ziebuhr J
,
Sotriffer C
,
Schirmeister T
. Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2. ChemMedChem. 2021 01 19; 16(2):340-354.
PMID:
32930481
.
Citations:
5
Fields:
Che
Chemistry
Pha
Pharmacology
Translation:
Animals
Cells
Morty RE
,
Ziebuhr J
. Call for Papers: The Pathophysiology of COVID-19 and SARS-CoV-2 Infection. Am J Physiol Lung Cell Mol Physiol. 2020 05 01; 318(5):L1016-L1019.
PMID:
32266822
.
Citations:
6
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Phy
Physiology
Pul
Pulmonary Medicine
Translation:
Humans
Cells
PH
Public Health
Viehweger A,
Krautwurst S
,
Lamkiewicz K
,
Madhugiri R
,
Ziebuhr J
,
Hölzer M
,
Marz M
. Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis. Genome Res. 2019 09; 29(9):1545-1554.
PMID:
31439691
.
Citations:
58
Fields:
Gen
Genetics
Translation:
Humans
Cells
Tvarogová J,
Madhugiri R
,
Bylapudi G
, Ferguson LJ,
Karl N
,
Ziebuhr J
. Identification and Characterization of a Human Coronavirus 229E Nonstructural Protein 8-Associated RNA 3'-Terminal Adenylyltransferase Activity. J Virol. 2019 06 15; 93(12).
PMID:
30918070
.
Citations:
28
Fields:
Vir
Virology
Translation:
Cells
Kanitz M, Blanck S, Heine A,
Gulyaeva AA
,
Gorbalenya AE
,
Ziebuhr J
, Diederich WE. Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus. Virology. 2019 07; 533:21-33.
PMID:
31078932
.
Citations:
3
Fields:
Vir
Virology
Translation:
Animals
Cells
Ehmann R
, Kristen-Burmann C, Bank-Wolf B, König M,
Herden C
, Hain T, Thiel HJ,
Ziebuhr J
,
Tekes G
. Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious Peritonitis. mBio. 2018 07 31; 9(4).
PMID:
30065095
.
Citations:
3
Fields:
Mic
Microbiology
Translation:
Animals
Cells
Durzynska I, Sauerwald M,
Karl N
,
Madhugiri R
,
Ziebuhr J
. Characterization of a bafinivirus exoribonuclease activity. J Gen Virol. 2018 09; 99(9):1253-1260.
PMID:
30058998
.
Citations:
4
Fields:
Vir
Virology
Translation:
Cells
Hassan DA, Rachid SK,
Ziebuhr J
. A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq. Glob Pediatr Health. 2018; 5:2333794X18784996.
PMID:
30014009
.
Citations:
2
Müller C
, Hardt M, Schwudke D,
Neuman BW
,
Pleschka S
,
Ziebuhr J
. Inhibition of Cytosolic Phospholipase A2a Impairs an Early Step of Coronavirus Replication in Cell Culture. J Virol. 2018 02 15; 92(4).
PMID:
29167338
.
Citations:
46
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Rappe JCF,
de Wilde A
, Di H,
Müller C
,
Stalder H
,
V'kovski P
,
Snijder E
,
Brinton MA
,
Ziebuhr J
,
Ruggli N
,
Thiel V
. Antiviral activity of K22 against members of the order Nidovirales. Virus Res. 2018 02 15; 246:28-34.
PMID:
29337162
.
Citations:
5
Fields:
Vir
Virology
Translation:
Animals
Cells
Müller C
, Schulte FW, Lange-Grünweller K,
Obermann W
,
Madhugiri R
,
Pleschka S
,
Ziebuhr J
,
Hartmann RK
,
Grünweller A
. Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses. Antiviral Res. 2018 02; 150:123-129.
PMID:
29258862
.
Citations:
64
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
Animals
Cells
Madhugiri R
,
Karl N
, Petersen D,
Lamkiewicz K
, Fricke M, Wend U, Scheuer R,
Marz M
,
Ziebuhr J
. Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions. Virology. 2018 04; 517:44-55.
PMID:
29223446
.
Citations:
21
Fields:
Vir
Virology
Translation:
Humans
Cells
Florek D,
Ehmann R
, Kristen-Burmann C, Lemmermeyer T,
Lochnit G
,
Ziebuhr J
, Thiel HJ,
Tekes G
. Identification and characterization of a Golgi retention signal in feline coronavirus accessory protein 7b. J Gen Virol. 2017 Aug; 98(8):2017-2029.
PMID:
28758629
.
Citations:
3
Fields:
Vir
Virology
Translation:
Animals
Cells
Poppe M, Wittig S, Jurida L, Bartkuhn M,
Wilhelm J
,
Müller H
, Beuerlein K,
Karl N
, Bhuju S,
Ziebuhr J
,
Schmitz ML
, Kracht M. The NF-?B-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells. PLoS Pathog. 2017 03; 13(3):e1006286.
PMID:
28355270
.
Citations:
30
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Kindler E
,
Gil-Cruz C
, Spanier J,
Li Y
,
Wilhelm J
, Rabouw HH,
Züst R
, Hwang M,
V'kovski P
,
Stalder H
, Marti S, Habjan M, Cervantes-Barragan L, Elliot R,
Karl N
, Gaughan C,
van Kuppeveld FJ
,
Silverman RH
,
Keller M
,
Ludewig B
,
Bergmann CC
,
Ziebuhr J
,
Weiss SR
, Kalinke U,
Thiel V
. Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog. 2017 02; 13(2):e1006195.
PMID:
28158275
.
Citations:
79
Fields:
Mic
Microbiology
Translation:
Humans
Animals
Cells
Snijder EJ
,
Decroly E
,
Ziebuhr J
. The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing. Adv Virus Res. 2016; 96:59-126.
PMID:
27712628
.
Citations:
167
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Madhugiri R
, Fricke M,
Marz M
,
Ziebuhr J
. Coronavirus cis-Acting RNA Elements. Adv Virus Res. 2016; 96:127-163.
PMID:
27712622
.
Citations:
32
Fields:
Vir
Virology
Translation:
Humans
Cells
Ziebuhr J
. Preface. Adv Virus Res. 2016; 96:xiii-xiv.
PMID:
27712629
.
Citations:
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Lemmermeyer T, Lamp B, Schneider R,
Ziebuhr J
,
Tekes G
, Thiel HJ. Characterization of monoclonal antibodies against feline coronavirus accessory protein 7b. Vet Microbiol. 2016 Feb 29; 184:11-9.
PMID:
26854339
.
Citations:
Fields:
Mic
Microbiology
Vet
Veterinary Medicine
Translation:
Animals
Cells
Madhugiri R
, Fricke M,
Marz M
,
Ziebuhr J
. RNA structure analysis of alphacoronavirus terminal genome regions. Virus Res. 2014 Dec 19; 194:76-89.
PMID:
25307890
.
Citations:
15
Fields:
Vir
Virology
Translation:
Cells
Paasche A, Zipper A, Schäfer S,
Ziebuhr J
,
Schirmeister T
, Engels B. Evidence for substrate binding-induced zwitterion formation in the catalytic Cys-His dyad of the SARS-CoV main protease. Biochemistry. 2014 Sep 23; 53(37):5930-46.
PMID:
25196915
.
Citations:
36
Fields:
Bio
Biochemistry
Translation:
Cells
Zhang Q, Standish I, Winters AD, Puzach C,
Ulferts R
,
Ziebuhr J
, Faisal M. Development and evaluation of reverse transcription loop-mediated isothermal amplification assay for the detection of the fathead minnow nidovirus. J Virol Methods. 2014 Jun; 202:39-45.
PMID:
24594288
.
Citations:
1
Fields:
Vir
Virology
Translation:
Animals
Cells
de Groot RJ
,
Baker SC
,
Baric RS
, Brown CS,
Drosten C
,
Enjuanes L
,
Fouchier RA
,
Galiano M
,
Gorbalenya AE
,
Memish ZA
,
Perlman S
,
Poon LL
,
Snijder EJ
, Stephens GM,
Woo PC
, Zaki AM,
Zambon M
,
Ziebuhr J
. Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol. 2013 Jul; 87(14):7790-2.
PMID:
23678167
.
Citations:
498
Fields:
Vir
Virology
Translation:
Humans
Cells
Zhao L, Jha BK, Wu A, Elliott R,
Ziebuhr J
,
Gorbalenya AE
,
Silverman RH
,
Weiss SR
. Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology. Cell Host Microbe. 2012 Jun 14; 11(6):607-16.
PMID:
22704621
.
Citations:
137
Fields:
Mic
Microbiology
Translation:
Animals
Cells
Kuri T, Eriksson KK, Putics A,
Züst R
,
Snijder EJ
,
Davidson AD
,
Siddell SG
,
Thiel V
,
Ziebuhr J
,
Weber F
. The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses. J Gen Virol. 2011 Aug; 92(Pt 8):1899-1905.
PMID:
21525212
.
Citations:
54
Fields:
Vir
Virology
Translation:
Humans
Cells
Züst R
, Cervantes-Barragan L, Habjan M, Maier R,
Neuman BW
,
Ziebuhr J
, Szretter KJ,
Baker SC
, Barchet W,
Diamond MS
,
Siddell SG
,
Ludewig B
,
Thiel V
. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol. 2011 Feb; 12(2):137-43.
PMID:
21217758
.
Citations:
341
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Nedialkova DD,
Ulferts R
, van den Born E, Lauber C,
Gorbalenya AE
,
Ziebuhr J
,
Snijder EJ
. Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease. J Virol. 2009 Jun; 83(11):5671-82.
PMID:
19297500
.
Citations:
57
Fields:
Vir
Virology
Translation:
Cells
Ziebuhr J
, Schelle B,
Karl N
, Minskaia E, Bayer S,
Siddell SG
,
Gorbalenya AE
,
Thiel V
. Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication. J Virol. 2007 Apr; 81(8):3922-32.
PMID:
17251282
.
Citations:
36
Fields:
Vir
Virology
Translation:
Humans
Cells
Schütze H,
Ulferts R
, Schelle B, Bayer S, Granzow H,
Hoffmann B
,
Mettenleiter TC
,
Ziebuhr J
. Characterization of White bream virus reveals a novel genetic cluster of nidoviruses. J Virol. 2006 Dec; 80(23):11598-609.
PMID:
16987966
.
Citations:
27
Fields:
Vir
Virology
Translation:
Cells
Egloff MP, Malet H, Putics A, Heinonen M, Dutartre H, Frangeul A, Gruez A, Campanacci V,
Cambillau C
,
Ziebuhr J
, Ahola T,
Canard B
. Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. J Virol. 2006 Sep; 80(17):8493-502.
PMID:
16912299
.
Citations:
128
Fields:
Vir
Virology
Translation:
Cells
Ricagno S, Egloff MP,
Ulferts R
,
Coutard B
, Nurizzo D, Campanacci V,
Cambillau C
,
Ziebuhr J
,
Canard B
. Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11892-7.
PMID:
16882730
.
Citations:
94
Fields:
Sci
Science
Translation:
Cells
Minskaia E, Hertzig T,
Gorbalenya AE
, Campanacci V,
Cambillau C
,
Canard B
,
Ziebuhr J
. Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):5108-13.
PMID:
16549795
.
Citations:
253
Fields:
Sci
Science
Translation:
Cells
Putics Á,
Gorbalenya AE
,
Ziebuhr J
. Identification of protease and ADP-ribose 1''-monophosphatase activities associated with transmissible gastroenteritis virus non-structural protein 3. J Gen Virol. 2006 Mar; 87(Pt 3):651-656.
PMID:
16476987
.
Citations:
26
Fields:
Vir
Virology
Translation:
Animals
Cells
Gorbalenya AE
,
Enjuanes L
,
Ziebuhr J
,
Snijder EJ
. Nidovirales: evolving the largest RNA virus genome. Virus Res. 2006 Apr; 117(1):17-37.
PMID:
16503362
.
Citations:
376
Fields:
Vir
Virology
Translation:
Cells
Ziebuhr J
. The coronavirus replicase: insights into a sophisticated enzyme machinery. Adv Exp Med Biol. 2006; 581:3-11.
PMID:
17037497
.
Citations:
14
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Cells
Ponnusamy R, Mesters JR,
Ziebuhr J
, Moll R,
Hilgenfeld R
. Non structural proteins 8 and 9 of human coronavirus 229E. Adv Exp Med Biol. 2006; 581:49-54.
PMID:
17037503
.
Citations:
2
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Cells
Putics A, Slaby J, Filipowicz W,
Gorbalenya AE
,
Ziebuhr J
. ADP-ribose-1"-phosphatase activities of the human coronavirus 229E and SARS coronavirus X domains. Adv Exp Med Biol. 2006; 581:93-6.
PMID:
17037511
.
Citations:
7
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Cells
Kaeppler U, Stiefl N, Schiller M, Vicik R, Breuning A, Schmitz W, Rupprecht D, Schmuck C, Baumann K,
Ziebuhr J
,
Schirmeister T
. A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods. J Med Chem. 2005 Nov 03; 48(22):6832-42.
PMID:
16250642
.
Citations:
25
Fields:
Che
Chemistry
Translation:
Cells
Martina E, Stiefl N, Degel B, Schulz F, Breuning A, Schiller M, Vicik R, Baumann K,
Ziebuhr J
,
Schirmeister T
. Screening of electrophilic compounds yields an aziridinyl peptide as new active-site directed SARS-CoV main protease inhibitor. Bioorg Med Chem Lett. 2005 Dec 15; 15(24):5365-9.
PMID:
16216498
.
Citations:
7
Fields:
Bio
Biochemistry
Che
Chemistry
Translation:
Humans
Cells
Putics A, Filipowicz W, Hall J,
Gorbalenya AE
,
Ziebuhr J
. ADP-ribose-1"-monophosphatase: a conserved coronavirus enzyme that is dispensable for viral replication in tissue culture. J Virol. 2005 Oct; 79(20):12721-31.
PMID:
16188975
.
Citations:
89
Fields:
Vir
Virology
Translation:
Animals
Cells
Yang H, Xie W, Xue X,
Yang K
, Ma J, Liang W, Zhao Q, Zhou Z,
Pei D
,
Ziebuhr J
,
Hilgenfeld R
,
Yuen KY
, Wong L, Gao G,
Chen S
, Chen Z, Ma D, Bartlam M,
Rao Z
. Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol. 2005 Oct; 3(10):e324.
PMID:
16128623
.
Citations:
219
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Seybert A,
Posthuma CC
, van Dinten LC,
Snijder EJ
,
Gorbalenya AE
,
Ziebuhr J
. A complex zinc finger controls the enzymatic activities of nidovirus helicases. J Virol. 2005 Jan; 79(2):696-704.
PMID:
15613297
.
Citations:
62
Fields:
Vir
Virology
Translation:
Cells
Ziebuhr J
. The coronavirus replicase. Curr Top Microbiol Immunol. 2005; 287:57-94.
PMID:
15609509
.
Citations:
163
Fields:
All
Allergy and Immunology
Mic
Microbiology
Translation:
Cells
Ivanov KA, Hertzig T, Rozanov M, Bayer S,
Thiel V
,
Gorbalenya AE
,
Ziebuhr J
. Major genetic marker of nidoviruses encodes a replicative endoribonuclease. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12694-9.
PMID:
15304651
.
Citations:
147
Fields:
Sci
Science
Translation:
Humans
Cells
Ziebuhr J
. Molecular biology of severe acute respiratory syndrome coronavirus. Curr Opin Microbiol. 2004 Aug; 7(4):412-9.
PMID:
15358261
.
Citations:
97
Fields:
Mic
Microbiology
Translation:
Humans
Animals
Cells
Ivanov KA,
Ziebuhr J
. Human coronavirus 229E nonstructural protein 13: characterization of duplex-unwinding, nucleoside triphosphatase, and RNA 5'-triphosphatase activities. J Virol. 2004 Jul; 78(14):7833-8.
PMID:
15220459
.
Citations:
85
Fields:
Vir
Virology
Translation:
Humans
Cells
Ivanov KA,
Thiel V
, Dobbe JC,
van der Meer Y
,
Snijder EJ
,
Ziebuhr J
. Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. J Virol. 2004 Jun; 78(11):5619-32.
PMID:
15140959
.
Citations:
176
Fields:
Vir
Virology
Translation:
Animals
Cells
Hertzig T, Scandella E, Schelle B,
Ziebuhr J
,
Siddell SG
,
Ludewig B
,
Thiel V
. Rapid identification of coronavirus replicase inhibitors using a selectable replicon RNA. J Gen Virol. 2004 Jun; 85(Pt 6):1717-1725.
PMID:
15166457
.
Citations:
33
Fields:
Vir
Virology
Translation:
Animals
Cells
Thiel V
, Ivanov KA, Putics Á, Hertzig T, Schelle B, Bayer S,
Weißbrich B
,
Snijder EJ
,
Rabenau H
, Doerr HW,
Gorbalenya AE
,
Ziebuhr J
. Mechanisms and enzymes involved in SARS coronavirus genome expression. J Gen Virol. 2003 Sep; 84(Pt 9):2305-2315.
PMID:
12917450
.
Citations:
374
Fields:
Vir
Virology
Translation:
Cells
Snijder EJ
,
Bredenbeek PJ
, Dobbe JC,
Thiel V
,
Ziebuhr J
,
Poon LL
,
Guan Y
, Rozanov M, Spaan WJ,
Gorbalenya AE
. Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol. 2003 Aug 29; 331(5):991-1004.
PMID:
12927536
.
Citations:
603
Fields:
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Ziebuhr J
. SARS--unprecedented global response to a newly emerging disease. Int J Med Microbiol. 2003 Aug; 293(4):229-31.
PMID:
14503787
.
Citations:
1
Fields:
Mic
Microbiology
Translation:
Humans
Cells
PH
Public Health
Anand K,
Ziebuhr J
, Wadhwani P, Mesters JR,
Hilgenfeld R
. Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science. 2003 Jun 13; 300(5626):1763-7.
PMID:
12746549
.
Citations:
563
Fields:
Sci
Science
Translation:
Humans
Cells
Ziebuhr J
. [Basically SARS is not a surprise. Coronaviruses lie in wait almost everywhere]. Krankenpfl J. 2003; 41(4-6):114-5.
PMID:
12929325
.
Citations:
Fields:
Nur
Nursing
Translation:
Animals
Cells
Ziebuhr J
, Bayer S, Cowley JA,
Gorbalenya AE
. The 3C-like proteinase of an invertebrate nidovirus links coronavirus and potyvirus homologs. J Virol. 2003 Jan; 77(2):1415-26.
PMID:
12502857
.
Citations:
22
Fields:
Vir
Virology
Translation:
Cells
Anand K, Palm GJ, Mesters JR,
Siddell SG
,
Ziebuhr J
,
Hilgenfeld R
. Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain. EMBO J. 2002 Jul 01; 21(13):3213-24.
PMID:
12093723
.
Citations:
229
Fields:
Bio
Biotechnology
Mol
Molecular Biology
Translation:
Cells
Hegyi A, Friebe A,
Gorbalenya AE
,
Ziebuhr J
. Mutational analysis of the active centre of coronavirus 3C-like proteases. J Gen Virol. 2002 Mar; 83(Pt 3):581-593.
PMID:
11842253
.
Citations:
26
Fields:
Vir
Virology
Translation:
Animals
Cells
Hegyi A,
Ziebuhr J
. Conservation of substrate specificities among coronavirus main proteases. J Gen Virol. 2002 Mar; 83(Pt 3):595-599.
PMID:
11842254
.
Citations:
90
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Ziebuhr J
,
Thiel V
,
Gorbalenya AE
. The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond. J Biol Chem. 2001 Aug 31; 276(35):33220-32.
PMID:
11431476
.
Citations:
74
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Seybert A,
Ziebuhr J
. Guanosine triphosphatase activity of the human coronavirus helicase. Adv Exp Med Biol. 2001; 494:255-60.
PMID:
11774478
.
Citations:
6
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Seybert A, van Dinten LC,
Snijder EJ
,
Ziebuhr J
. Biochemical characterization of the equine arteritis virus helicase suggests a close functional relationship between arterivirus and coronavirus helicases. J Virol. 2000 Oct; 74(20):9586-93.
PMID:
11000230
.
Citations:
39
Fields:
Vir
Virology
Translation:
Cells
Seybert A, Hegyi A,
Siddell SG
,
Ziebuhr J
. The human coronavirus 229E superfamily 1 helicase has RNA and DNA duplex-unwinding activities with 5'-to-3' polarity. RNA. 2000 Jul; 6(7):1056-68.
PMID:
10917600
.
Citations:
75
Fields:
Mol
Molecular Biology
Translation:
Animals
Cells
Ziebuhr J
,
Siddell SG
. Processing of the human coronavirus 229E replicase polyproteins by the virus-encoded 3C-like proteinase: identification of proteolytic products and cleavage sites common to pp1a and pp1ab. J Virol. 1999 Jan; 73(1):177-85.
PMID:
9847320
.
Citations:
40
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Ziebuhr J
, Heusipp G, Seybert A,
Siddell SG
. Substrate specificity of the human coronavirus 229E 3C-like proteinase. Adv Exp Med Biol. 1998; 440:115-20.
PMID:
9782272
.
Citations:
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Cells
Heusipp G, Grötzinger C, Herold J,
Siddell SG
,
Ziebuhr J
. Identification and subcellular localization of a 41 kDa, polyprotein 1ab processing product in human coronavirus 229E-infected cells. J Gen Virol. 1997 Nov; 78 ( Pt 11):2789-94.
PMID:
9367364
.
Citations:
20
Fields:
Vir
Virology
Translation:
Humans
Cells
Heusipp G, Harms U,
Siddell SG
,
Ziebuhr J
. Identification of an ATPase activity associated with a 71-kilodalton polypeptide encoded in gene 1 of the human coronavirus 229E. J Virol. 1997 Jul; 71(7):5631-4.
PMID:
9188639
.
Citations:
20
Fields:
Vir
Virology
Translation:
Humans
Cells
Ziebuhr J
, Heusipp G,
Siddell SG
. Biosynthesis, purification, and characterization of the human coronavirus 229E 3C-like proteinase. J Virol. 1997 May; 71(5):3992-7.
PMID:
9094676
.
Citations:
38
Fields:
Vir
Virology
Translation:
Humans
Cells
Seybert A,
Ziebuhr J
,
Siddell SG
. Expression and characterization of a recombinant murine coronavirus 3C-like proteinase. J Gen Virol. 1997 Jan; 78 ( Pt 1):71-5.
PMID:
9010287
.
Citations:
8
Fields:
Vir
Virology
Translation:
Animals
Cells
Grötzinger C, Heusipp G,
Ziebuhr J
, Harms U, Süss J,
Siddell SG
. Characterization of a 105-kDa polypeptide encoded in gene 1 of the human coronavirus HCV 229E. Virology. 1996 Aug 01; 222(1):227-35.
PMID:
8806502
.
Citations:
17
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Herold J,
Siddell S
,
Ziebuhr J
. Characterization of coronavirus RNA polymerase gene products. Methods Enzymol. 1996; 275:68-89.
PMID:
9026661
.
Citations:
12
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Ziebuhr J
, Herold J,
Siddell SG
. Characterization of a human coronavirus (strain 229E) 3C-like proteinase activity. J Virol. 1995 Jul; 69(7):4331-8.
PMID:
7769694
.
Citations:
49
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
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