Andrew Ward to Humans
This is a "connection" page, showing publications Andrew Ward has written about Humans.
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Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization. Sci Adv. 2021 07; 7(31).
Score: 0.008
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Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. Science. 2020 11 27; 370(6520):1089-1094.
Score: 0.007
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Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex. Acta Crystallogr F Struct Biol Commun. 2019 May 01; 75(Pt 5):340-347.
Score: 0.007
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Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep. 2018 10 24; 8(1):15701.
Score: 0.006
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The 2017 Keystone Symposium on HIV Vaccines. Hum Vaccin Immunother. 2017 10 03; 13(10):2348-2351.
Score: 0.006
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Time-course, negative-stain electron microscopy-based analysis for investigating protein-protein interactions at the single-molecule level. J Biol Chem. 2017 11 24; 292(47):19400-19410.
Score: 0.006
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A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic ß-Hairpin Structure. Immunity. 2017 04 18; 46(4):690-702.
Score: 0.006
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The HIV-1 envelope glycoprotein structure: nailing down a moving target. Immunol Rev. 2017 01; 275(1):21-32.
Score: 0.006
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Pre-fusion structure of a human coronavirus spike protein. Nature. 2016 Mar 03; 531(7592):118-21.
Score: 0.005
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Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo in a Mouse Model in a Neutralization-Dependent Manner. mBio. 2021 08 31; 12(4):e0100221.
Score: 0.002
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Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Cell Rep. 2021 07 13; 36(2):109353.
Score: 0.002
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Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science. 2021 08 13; 373(6556):818-823.
Score: 0.002
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Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. Nat Commun. 2021 05 19; 12(1):2938.
Score: 0.002
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A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host Microbe. 2021 05 12; 29(5):806-818.e6.
Score: 0.002
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Extremely potent human monoclonal antibodies from COVID-19 convalescent patients. Cell. 2021 04 01; 184(7):1821-1835.e16.
Score: 0.002
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Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins. PLoS Pathog. 2021 02; 17(2):e1009282.
Score: 0.002
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A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. PLoS Pathog. 2020 12; 16(12):e1009089.
Score: 0.002
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Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity. 2020 12 15; 53(6):1272-1280.e5.
Score: 0.002
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An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Rep. 2020 10 20; 33(3):108274.
Score: 0.002
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2. Cell. 2020 11 12; 183(4):1043-1057.e15.
Score: 0.002
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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Science. 2020 08 07; 369(6504):643-650.
Score: 0.002
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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation. Nat Commun. 2020 05 27; 11(1):2688.
Score: 0.002
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Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD. Cell Rep. 2019 09 24; 28(13):3395-3405.e6.
Score: 0.002
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Field-Based Affinity Optimization of a Novel Azabicyclohexane Scaffold HIV-1 Entry Inhibitor. Molecules. 2019 Apr 22; 24(8).
Score: 0.002
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Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens. J Pharm Sci. 2019 07; 108(7):2264-2277.
Score: 0.002
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Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S612-S626.
Score: 0.002
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HIV-1 vaccine design through minimizing envelope metastability. Sci Adv. 2018 11; 4(11):eaau6769.
Score: 0.002
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OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels. Elife. 2018 11 01; 7.
Score: 0.002
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Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer. Nat Commun. 2018 09 12; 9(1):3693.
Score: 0.002
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Structure of the human volume regulated anion channel. Elife. 2018 08 10; 7.
Score: 0.002
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Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity. 2018 08 21; 49(2):288-300.e8.
Score: 0.002
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Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018 08 21; 49(2):363-374.e10.
Score: 0.002
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A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 07 10; 9(1):2669.
Score: 0.002
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Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro. J Virol. 2018 07 01; 92(13).
Score: 0.002
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Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies. Front Immunol. 2018; 9:1116.
Score: 0.002
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Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nat Commun. 2018 05 16; 9(1):1956.
Score: 0.002
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Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. PLoS Pathog. 2018 05; 14(5):e1006986.
Score: 0.002
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Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nat Microbiol. 2018 06; 3(6):670-677.
Score: 0.002
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Glycosylation of Human IgA Directly Inhibits Influenza A and Other Sialic-Acid-Binding Viruses. Cell Rep. 2018 04 03; 23(1):90-99.
Score: 0.002
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Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity. Nat Commun. 2018 02 28; 9(1):877.
Score: 0.002
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Envelope proteins of two HIV-1 clades induced different epitope-specific antibody response. Vaccine. 2018 03 14; 36(12):1627-1636.
Score: 0.002
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Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers. J Biol Chem. 2018 02 02; 293(5):1688-1701.
Score: 0.001
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Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nat Commun. 2017 11 21; 8(1):1655.
Score: 0.001
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Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):E10438-E10445.
Score: 0.001
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High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers. J Virol. 2017 11 15; 91(22).
Score: 0.001
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HIV-1 Cross-Reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Nonhuman Primates. J Virol. 2017 11 01; 91(21).
Score: 0.001
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Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Rep. 2017 Oct 03; 21(1):222-235.
Score: 0.001
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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. J Exp Med. 2017 Sep 04; 214(9):2573-2590.
Score: 0.001
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Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Sci Rep. 2017 08 21; 7(1):8390.
Score: 0.001
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Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):E7348-E7357.
Score: 0.001
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Characterization of a stable HIV-1 B/C recombinant, soluble, and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes. J Biol Chem. 2017 09 22; 292(38):15849-15858.
Score: 0.001
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Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers. J Virol. 2017 08 01; 91(15).
Score: 0.001
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Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 2017 06 20; 46(6):1073-1088.e6.
Score: 0.001
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Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes. J Virol. 2017 06 15; 91(12).
Score: 0.001
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Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses. Cell. 2017 May 18; 169(5):878-890.e15.
Score: 0.001
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Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 2017 05 16; 46(5):777-791.e10.
Score: 0.001
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Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity. 2017 05 16; 46(5):792-803.e3.
Score: 0.001
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In vitro evolution of an influenza broadly neutralizing antibody is modulated by hemagglutinin receptor specificity. Nat Commun. 2017 05 15; 8:15371.
Score: 0.001
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Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus. Cell Rep. 2017 04 11; 19(2):413-424.
Score: 0.001
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Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein. J Biol Chem. 2017 05 19; 292(20):8236-8243.
Score: 0.001
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Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. PLoS Pathog. 2017 01; 13(1):e1006074.
Score: 0.001
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A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science. 2014 Feb 07; 343(6171):656-661.
Score: 0.001
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Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep. 2013 Dec 12; 5(5):1443-55.
Score: 0.001