Gary R Whittaker

InstitutionCornell University
AddressIthaca
New York
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 19 Covid-19 publications, with a maximum of 2 publications in April 2020 and October 2020 and January 2021 and February 2021 and April 2021
    All Publications
    Bar chart showing 100 publications over 23 distinct years, with a maximum of 10 publications in 2021
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Whittaker GR. SARS-CoV-2 spike and its adaptable furin cleavage site. Lancet Microbe. 2021 Oct; 2(10):e488-e489. PMID: 34396356.
      Citations: 3     
    2. Stout AE, Millet JK, Stanhope MJ, Whittaker GR. Furin cleavage sites in the spike proteins of bat and rodent coronaviruses: Implications for virus evolution and zoonotic transfer from rodent species. One Health. 2021 Dec; 13:100282. PMID: 34179330.
      Citations:    
    3. Millet JK, Jaimes JA, Whittaker GR. Molecular diversity of coronavirus host cell entry receptors. FEMS Microbiol Rev. 2021 05 05; 45(3). PMID: 33118022.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    4. Stout AE, André NM, Jaimes JA, Licitra BN, Whittaker GR. One Medicine: a comparative approach to investigating human and animal coronavirus infections. J Feline Med Surg. 2021 04; 23(4):267-268. PMID: 33761776.
      Citations: 1     Fields:    
    5. Stout AE, André NM, Whittaker GR. FELINE CORONAVIRUS AND FELINE INFECTIOUS PERITONITIS IN NONDOMESTIC FELID SPECIES. J Zoo Wildl Med. 2021 Apr; 52(1):14-27. PMID: 33827157.
      Citations:    Fields:    Translation:AnimalsCells
    6. Whittaker GR, Daniel S, Millet JK. Coronavirus entry: how we arrived at SARS-CoV-2. Curr Opin Virol. 2021 04; 47:113-120. PMID: 33744490.
      Citations: 12     Fields:    Translation:HumansCells
    7. Lesser K, Whittaker GR. Vaccination for COVID-19: benchmarks in public health and virus transmission. Public Health. 2021 08; 197:e23. PMID: 33771367.
      Citations: 1     Fields:    
    8. Rendon-Marin S, Martinez-Gutierrez M, Whittaker GR, Jaimes JA, Ruiz-Saenz J. SARS CoV-2 Spike Protein in silico Interaction With ACE2 Receptors From Wild and Domestic Species. Front Genet. 2021; 12:571707. PMID: 33659022.
      Citations: 5     
    9. Stout AE, Guo Q, Millet JK, de Matos R, Whittaker GR. Coronaviruses Associated with the Superfamily Musteloidea. mBio. 2021 01 19; 12(1). PMID: 33468694.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    10. Tang T, Jaimes JA, Bidon MK, Straus MR, Daniel S, Whittaker GR. Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin. ACS Infect Dis. 2021 02 12; 7(2):264-272. PMID: 33432808.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    11. Ghosh S, Dellibovi-Ragheb TA, Kerviel A, Pak E, Qiu Q, Fisher M, Takvorian PM, Bleck C, Hsu VW, Fehr AR, Perlman S, Achar SR, Straus MR, Whittaker GR, de Haan CAM, Kehrl J, Altan-Bonnet G, Altan-Bonnet N. ß-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell. 2020 12 10; 183(6):1520-1535.e14. PMID: 33157038.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    12. Chen CZ, Xu M, Pradhan M, Gorshkov K, Petersen JD, Straus MR, Zhu W, Shinn P, Guo H, Shen M, Klumpp-Thomas C, Michael SG, Zimmerberg J, Zheng W, Whittaker GR. Identifying SARS-CoV-2 Entry Inhibitors through Drug Repurposing Screens of SARS-S and MERS-S Pseudotyped Particles. ACS Pharmacol Transl Sci. 2020 Dec 11; 3(6):1165-1175. PMID: 33330839.
      Citations: 20     
    13. Whittaker GR, Daniel S. Going back in time for an antibody to fight COVID-19. Nature. 2020 07; 583(7815):203-204. PMID: 32623442.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    14. Stout AE, André NM, Jaimes JA, Millet JK, Whittaker GR. Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? Vet Microbiol. 2020 Aug; 247:108777. PMID: 32768223.
      Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    15. Jaimes JA, Millet JK, Whittaker GR. Proteolytic Cleavage of the SARS-CoV-2 Spike Protein and the Role of the Novel S1/S2 Site. iScience. 2020 Jun 26; 23(6):101212. PMID: 32512386.
      Citations: 93     
    16. Jaimes JA, André NM, Chappie JS, Millet JK, Whittaker GR. Phylogenetic Analysis and Structural Modeling of SARS-CoV-2 Spike Protein Reveals an Evolutionary Distinct and Proteolytically Sensitive Activation Loop. J Mol Biol. 2020 05 01; 432(10):3309-3325. PMID: 32320687.
      Citations: 169     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    17. Tang T, Bidon M, Jaimes JA, Whittaker GR, Daniel S. Coronavirus membrane fusion mechanism offers a potential target for antiviral development. Antiviral Res. 2020 06; 178:104792. PMID: 32272173.
      Citations: 207     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Jaimes JA, Millet JK, Stout AE, André NM, Whittaker GR. A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses. Viruses. 2020 01 10; 12(1). PMID: 31936749.
      Citations: 32     Fields:    Translation:AnimalsCells
    19. Whittaker GR, Millet JK. Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Spike Protein Proteolytic Processing. Methods Mol Biol. 2020; 2099:21-37. PMID: 31883085.
      Citations: 5     Fields:    Translation:HumansCells
    20. Mettelman RC, O'Brien A, Whittaker GR, Baker SC. Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus. Virology. 2019 11; 537:226-236. PMID: 31539770.
      Citations: 5     Fields:    Translation:AnimalsCells
    21. André NM, Cossic B, Davies E, Miller AD, Whittaker GR. Distinct mutation in the feline coronavirus spike protein cleavage activation site in a cat with feline infectious peritonitis-associated meningoencephalomyelitis. JFMS Open Rep. 2019 Jan-Jun; 5(1):2055116919856103. PMID: 31534775.
      Citations: 11     
    22. Millet JK, Tang T, Nathan L, Jaimes JA, Hsu HL, Daniel S, Whittaker GR. Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting. J Vis Exp. 2019 03 01; (145). PMID: 30882796.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    23. Jaimes JA, Millet JK, Goldstein ME, Whittaker GR, Straus MR. A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation. J Vis Exp. 2019 01 09; (143). PMID: 30688313.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    24. O'Brien A, Mettelman RC, Volk A, André NM, Whittaker GR, Baker SC. Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines. Virology. 2018 12; 525:1-9. PMID: 30205273.
      Citations: 6     Fields:    Translation:AnimalsCells
    25. Jaimes JA, Whittaker GR. Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function. Virology. 2018 04; 517:108-121. PMID: 29329682.
      Citations: 25     Fields:    Translation:AnimalsCells
    26. Whittaker GR, André NM, Millet JK. Improving Virus Taxonomy by Recontextualizing Sequence-Based Classification with Biologically Relevant Data: the Case of the Alphacoronavirus 1 Species. mSphere. 2018 Jan-Feb; 3(1). PMID: 29299531.
      Citations: 14     Fields:    
    27. Millet JK, Whittaker GR. Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells. Virology. 2018 04; 517:3-8. PMID: 29275820.
      Citations: 94     Fields:    Translation:HumansCells
    28. Lai AL, Millet JK, Daniel S, Freed JH, Whittaker GR. The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner. J Mol Biol. 2017 12 08; 429(24):3875-3892. PMID: 29056462.
      Citations: 57     Fields:    Translation:HumansCells
    29. Millet JK, Goldstein ME, Labitt RN, Hsu HL, Daniel S, Whittaker GR. A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties. Emerg Microbes Infect. 2016 Dec 21; 5(12):e126. PMID: 27999426.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    30. Millet JK, Whittaker GR. Murine Leukemia Virus (MLV)-based Coronavirus Spike-pseudotyped Particle Production and Infection. Bio Protoc. 2016 Dec 05; 6(23). PMID: 28018942.
      Citations: 31     
    31. Millet JK, Séron K, Labitt RN, Danneels A, Palmer KE, Whittaker GR, Dubuisson J, Belouzard S. Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin. Antiviral Res. 2016 09; 133:1-8. PMID: 27424494.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    32. Millet JK, Whittaker GR. Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis. Virus Res. 2015 Apr 16; 202:120-34. PMID: 25445340.
      Citations: 348     Fields:    Translation:HumansCells
    33. Millet JK, Whittaker GR. Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15214-9. PMID: 25288733.
      Citations: 279     Fields:    Translation:HumansAnimalsCells
    34. Licitra BN, Whittaker GR, Dubovi EJ, Duhamel GE. Genotypic characterization of canine coronaviruses associated with fatal canine neonatal enteritis in the United States. J Clin Microbiol. 2014 Dec; 52(12):4230-8. PMID: 25253797.
      Citations: 8     Fields:    Translation:AnimalsCells
    35. Licitra BN, Duhamel GE, Whittaker GR. Canine enteric coronaviruses: emerging viral pathogens with distinct recombinant spike proteins. Viruses. 2014 Aug 22; 6(8):3363-76. PMID: 25153347.
      Citations: 28     Fields:    Translation:AnimalsCells
    36. Costello DA, Millet JK, Hsia CY, Whittaker GR, Daniel S. Single particle assay of coronavirus membrane fusion with proteinaceous receptor-embedded supported bilayers. Biomaterials. 2013 Oct; 34(32):7895-904. PMID: 23886734.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    37. Licitra BN, Millet JK, Regan AD, Hamilton BS, Rinaldi VD, Duhamel GE, Whittaker GR. Mutation in spike protein cleavage site and pathogenesis of feline coronavirus. Emerg Infect Dis. 2013 Jul; 19(7):1066-73. PMID: 23763835.
      Citations: 61     Fields:    Translation:AnimalsCells
    38. Belouzard S, Millet JK, Licitra BN, Whittaker GR. Mechanisms of coronavirus cell entry mediated by the viral spike protein. Viruses. 2012 06; 4(6):1011-33. PMID: 22816037.
      Citations: 420     Fields:    Translation:HumansAnimalsCells
    39. Regan AD, Millet JK, Tse LP, Chillag Z, Rinaldi VD, Licitra BN, Dubovi EJ, Town CD, Whittaker GR. Characterization of a recombinant canine coronavirus with a distinct receptor-binding (S1) domain. Virology. 2012 Sep 01; 430(2):90-9. PMID: 22609354.
      Citations: 15     Fields:    Translation:AnimalsCells
    40. Zhang Y, Buckles E, Whittaker GR. Expression of the C-type lectins DC-SIGN or L-SIGN alters host cell susceptibility for the avian coronavirus, infectious bronchitis virus. Vet Microbiol. 2012 Jun 15; 157(3-4):285-93. PMID: 22340967.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    41. Belouzard S, Madu I, Whittaker GR. Elastase-mediated activation of the severe acute respiratory syndrome coronavirus spike protein at discrete sites within the S2 domain. J Biol Chem. 2010 Jul 23; 285(30):22758-63. PMID: 20507992.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    42. Regan AD, Ousterout DG, Whittaker GR. Feline lectin activity is critical for the cellular entry of feline infectious peritonitis virus. J Virol. 2010 Aug; 84(15):7917-21. PMID: 20484511.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    43. Madu IG, Belouzard S, Whittaker GR. SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion. Virology. 2009 Oct 25; 393(2):265-71. PMID: 19717178.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    44. Madu IG, Roth SL, Belouzard S, Whittaker GR. Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide. J Virol. 2009 Aug; 83(15):7411-21. PMID: 19439480.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    45. Belouzard S, Chu VC, Whittaker GR. Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5871-6. PMID: 19321428.
      Citations: 412     Fields:    Translation:Cells
    46. Regan AD, Cohen RD, Whittaker GR. Activation of p38 MAPK by feline infectious peritonitis virus regulates pro-inflammatory cytokine production in primary blood-derived feline mononuclear cells. Virology. 2009 Feb 05; 384(1):135-43. PMID: 19058829.
      Citations: 21     Fields:    Translation:AnimalsCells
    47. Regan AD, Whittaker GR. Utilization of DC-SIGN for entry of feline coronaviruses into host cells. J Virol. 2008 Dec; 82(23):11992-6. PMID: 18799586.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    48. Regan AD, Shraybman R, Cohen RD, Whittaker GR. Differential role for low pH and cathepsin-mediated cleavage of the viral spike protein during entry of serotype II feline coronaviruses. Vet Microbiol. 2008 Dec 10; 132(3-4):235-48. PMID: 18606506.
      Citations: 36     Fields:    Translation:AnimalsCells
    49. Madu IG, Chu VC, Lee H, Regan AD, Bauman BE, Whittaker GR. Heparan sulfate is a selective attachment factor for the avian coronavirus infectious bronchitis virus Beaudette. Avian Dis. 2007 Mar; 51(1):45-51. PMID: 17461266.
      Citations: 39     Fields:    Translation:AnimalsCells
    50. Chu VC, McElroy LJ, Aronson JM, Oura TJ, Harbison CE, Bauman BE, Whittaker GR. Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus. Virol J. 2007 Feb 26; 4:20. PMID: 17324273.
      Citations: 4     Fields:    Translation:AnimalsCells
    51. Chu VC, McElroy LJ, Chu V, Bauman BE, Whittaker GR. The avian coronavirus infectious bronchitis virus undergoes direct low-pH-dependent fusion activation during entry into host cells. J Virol. 2006 Apr; 80(7):3180-8. PMID: 16537586.
      Citations: 39     Fields:    Translation:AnimalsCells
    52. Chu VC, McElroy LJ, Bauman BE, Whittaker GR. Fluorescence dequenching assays of coronavirus fusion. Adv Exp Med Biol. 2006; 581:241-6. PMID: 17037536.
      Citations: 1     Fields:    Translation:AnimalsCells
    53. Chu VC, McElroy LJ, Ferguson AD, Bauman BE, Whittaker GR. Avian infectious bronchitis virus enters cells via the endocytic pathway. Adv Exp Med Biol. 2006; 581:309-12. PMID: 17037550.
      Citations: 3     Fields:    Translation:AnimalsCells
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