Co-Authors
This is a "connection" page, showing publications co-authored by Timothy Sheahan and Ralph Baric.
Connection Strength
8.460
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An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 04 29; 12(541).
Score: 0.876
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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nat Commun. 2020 01 10; 11(1):222.
Score: 0.861
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Is regulation preventing the development of therapeutics that may prevent future coronavirus pandemics? Future Virol. 2018 Mar; 13(3):143-146.
Score: 0.756
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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med. 2017 06 28; 9(396).
Score: 0.722
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Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. J Virol. 2011 Jan; 85(1):217-30.
Score: 0.455
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Pathways of cross-species transmission of synthetically reconstructed zoonotic severe acute respiratory syndrome coronavirus. J Virol. 2008 Sep; 82(17):8721-32.
Score: 0.387
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Mechanisms of zoonotic severe acute respiratory syndrome coronavirus host range expansion in human airway epithelium. J Virol. 2008 Mar; 82(5):2274-85.
Score: 0.373
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Resurrection of an "extinct" SARS-CoV isolate GD03 from late 2003. Adv Exp Med Biol. 2006; 581:547-50.
Score: 0.326
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Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice. Cell Rep. 2021 07 27; 36(4):109450.
Score: 0.239
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Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication. mBio. 2021 03 16; 12(2).
Score: 0.234
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Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo. J Exp Med. 2021 03 01; 218(3).
Score: 0.233
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Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. 2021 Feb; 590(7844):E22.
Score: 0.232
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A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell. 2020 11 12; 183(4):1070-1085.e12.
Score: 0.226
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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. 2020 10; 586(7830):560-566.
Score: 0.225
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Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Rep. 2020 07 21; 32(3):107940.
Score: 0.223
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Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis. PLoS One. 2019; 14(7):e0220126.
Score: 0.208
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Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase. Antiviral Res. 2019 09; 169:104541.
Score: 0.207
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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis. mBio. 2018 10 09; 9(5).
Score: 0.197
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Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion. mSphere. 2018 Jan-Feb; 3(1).
Score: 0.188
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SARS-like WIV1-CoV poised for human emergence. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):3048-53.
Score: 0.165
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Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J Infect Dis. 2010 Mar 15; 201(6):946-55.
Score: 0.109
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MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. PLoS Pathog. 2008 Dec; 4(12):e1000240.
Score: 0.100
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Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. J Virol. 2008 Apr; 82(7):3220-35.
Score: 0.094
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Synthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice. J Virol. 2007 Jul; 81(14):7410-23.
Score: 0.090
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Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease. Virus Res. 2008 Apr; 133(1):45-62.
Score: 0.089
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Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants. PLoS Med. 2006 Dec; 3(12):e525.
Score: 0.087
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SARS coronavirus vaccine development. Adv Exp Med Biol. 2006; 581:553-60.
Score: 0.081
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Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 09; 28(9):747-754.
Score: 0.060
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ß-d-N4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells. J Infect Dis. 2021 08 02; 224(3):415-419.
Score: 0.060
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Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Mol Cell. 2020 12 17; 80(6):1078-1091.e6.
Score: 0.057
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Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2. Cell. 2020 11 25; 183(5):1367-1382.e17.
Score: 0.057
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Small-Molecule Antiviral ß-d-N4-Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance. J Virol. 2019 12 15; 93(24).
Score: 0.053
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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. mBio. 2018 03 06; 9(2).
Score: 0.047
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Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. J Virol. 2009 Jul; 83(14):7062-74.
Score: 0.026
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Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19944-9.
Score: 0.025
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A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. J Virol. 2008 Aug; 82(15):7721-4.
Score: 0.024
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Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12123-8.
Score: 0.023
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Animal models and vaccines for SARS-CoV infection. Virus Res. 2008 Apr; 133(1):20-32.
Score: 0.022
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A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice. PLoS Pathog. 2007 Jan; 3(1):e5.
Score: 0.022