Matthew B Frieman

InstitutionUniversity of Maryland School of Medicine
AddressBaltimore
Maryland
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 20 Covid-19 publications, with a maximum of 3 publications in Spetember 2020 and October 2020
    All Publications
    Bar chart showing 86 publications over 20 distinct years, with a maximum of 13 publications in 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Frieman M, Harris AD, Herati RS, Krammer F, Mantovani A, Rescigno M, Sajadi MM, Simon V. SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors. EBioMedicine. 2021 Jun; 68:103401. PMID: 34051441.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    2. Si L, Bai H, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, Nilsson-Payant BE, Golynker I, Frere J, Logue J, Haupt R, McGrath M, Weston S, Zhang T, Plebani R, Soong M, Nurani A, Kim SM, Zhu DY, Benam KH, Goyal G, Gilpin SE, Prantil-Baun R, Gygi SP, Powers RK, Carlson KE, Frieman M, tenOever BR, Ingber DE. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nat Biomed Eng. 2021 08; 5(8):815-829. PMID: 33941899.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    3. Citations: 16     Fields:    Translation:HumansAnimalsCells
    4. Saadat S, Rikhtegaran Tehrani Z, Logue J, Newman M, Frieman MB, Harris AD, Sajadi MM. Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2. JAMA. 2021 04 13; 325(14):1467-1469. PMID: 33646292.
      Citations: 83     Fields:    Translation:Humans
    5. Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Fintelman-Rodrigues N, Tavella TA, Maranhão Costa FT, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, Levi JA, Johnson NJ, Kisthardt SC, Scholle F, Souza TML, Moorman NJ, Baric RS, Madrid PB, Ekins S. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms. ACS Omega. 2021 Mar 23; 6(11):7454-7468. PMID: 33778258.
      Citations: 12     
    6. Koff WC, Schenkelberg T, Williams T, Baric RS, McDermott A, Cameron CM, Cameron MJ, Friemann MB, Neumann G, Kawaoka Y, Kelvin AA, Ross TM, Schultz-Cherry S, Mastro TD, Priddy FH, Moore KA, Ostrowsky JT, Osterholm MT, Goudsmit J. Development and deployment of COVID-19 vaccines for those most vulnerable. Sci Transl Med. 2021 02 03; 13(579). PMID: 33536277.
      Citations: 9     Fields:    Translation:HumansAnimals
    7. Tian JH, Patel N, Haupt R, Zhou H, Weston S, Hammond H, Logue J, Portnoff AD, Norton J, Guebre-Xabier M, Zhou B, Jacobson K, Maciejewski S, Khatoon R, Wisniewska M, Moffitt W, Kluepfel-Stahl S, Ekechukwu B, Papin J, Boddapati S, Jason Wong C, Piedra PA, Frieman MB, Massare MJ, Fries L, Bengtsson KL, Stertman L, Ellingsworth L, Glenn G, Smith G. SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice. Nat Commun. 2021 01 14; 12(1):372. PMID: 33446655.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    8. Weston S, Baracco L, Keller C, Matthews K, McGrath ME, Logue J, Liang J, Dyall J, Holbrook MR, Hensley LE, Jahrling PB, Yu W, MacKerell AD, Frieman MB. The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses. Proc Natl Acad Sci U S A. 2020 12 01; 117(48):30687-30698. PMID: 33184176.
      Citations: 3     Fields:    Translation:AnimalsCells
    9. Guebre-Xabier M, Patel N, Tian JH, Zhou B, Maciejewski S, Lam K, Portnoff AD, Massare MJ, Frieman MB, Piedra PA, Ellingsworth L, Glenn G, Smith G. NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge. Vaccine. 2020 11 25; 38(50):7892-7896. PMID: 33139139.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    10. Citations: 143     Fields:    Translation:HumansCells
    11. Weston S, Coleman CM, Haupt R, Logue J, Matthews K, Li Y, Reyes HM, Weiss SR, Frieman MB. Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 In Vitro and SARS-CoV In Vivo. J Virol. 2020 10 14; 94(21). PMID: 32817221.
      Citations: 73     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Miller K, McGrath ME, Hu Z, Ariannejad S, Weston S, Frieman M, Jackson WT. Coronavirus interactions with the cellular autophagy machinery. Autophagy. 2020 12; 16(12):2131-2139. PMID: 32964796.
      Citations: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    13. Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, Segalés J, Vasan SS, et al. Animal models for COVID-19. Nature. 2020 10; 586(7830):509-515. PMID: 32967005.
      Citations: 181     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Keech C, Albert G, Cho I, Robertson A, Reed P, Neal S, Plested JS, Zhu M, Cloney-Clark S, Zhou H, Smith G, Patel N, Frieman MB, Haupt RE, Logue J, McGrath M, Weston S, Piedra PA, Desai C, Callahan K, Lewis M, Price-Abbott P, Formica N, Shinde V, Fries L, Lickliter JD, Griffin P, Wilkinson B, Glenn GM. Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine. N Engl J Med. 2020 12 10; 383(24):2320-2332. PMID: 32877576.
      Citations: 325     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    15. Funnell SGP, Dowling WE, Muñoz-Fontela C, Gsell PS, Ingber DE, Hamilton GA, Delang L, Rocha-Pereira J, Kaptein S, Dallmeier KH, Neyts J, Rosenke K, de Wit E, Feldmann H, Maisonnasse P, Le Grand R, Le Grand R, Frieman MB, Coleman CM. Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients. Nat Commun. 2020 08 26; 11(1):4253. PMID: 32848158.
      Citations: 21     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Citations: 337     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    17. Sheahan TP, Frieman MB. The continued epidemic threat of SARS-CoV-2 and implications for the future of global public health. Curr Opin Virol. 2020 02; 40:37-40. PMID: 32569751.
      Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Moitra P, Alafeef M, Dighe K, Frieman MB, Pan D. Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles. ACS Nano. 2020 06 23; 14(6):7617-7627. PMID: 32437124.
      Citations: 133     Fields:    Translation:HumansCellsPHPublic Health
    19. Hu TY, Frieman M, Wolfram J. Insights from nanomedicine into chloroquine efficacy against COVID-19. Nat Nanotechnol. 2020 04; 15(4):247-249. PMID: 32203437.
      Citations: 115     Fields:    Translation:HumansCellsPHPublic Health
    20. Weston S, Frieman MB. COVID-19: Knowns, Unknowns, and Questions. mSphere. 2020 03 18; 5(2). PMID: 32188753.
      Citations: 51     Fields:    Translation:HumansCellsPHPublic Health
    21. Kulcsar KA, Coleman CM, Beck SE, Frieman MB. Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection. JCI Insight. 2019 10 17; 4(20). PMID: 31550243.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    22. Weston S, Matthews KL, Lent R, Vlk A, Haupt R, Kingsbury T, Frieman MB. A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication. J Virol. 2019 08 15; 93(16). PMID: 31142674.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    23. Banerjee A, Kulcsar K, Misra V, Frieman M, Mossman K. Bats and Coronaviruses. Viruses. 2019 01 09; 11(1). PMID: 30634396.
      Citations: 117     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    24. Cong Y, Hart BJ, Gross R, Zhou H, Frieman M, Bollinger L, Wada J, Hensley LE, Jahrling PB, Dyall J, Holbrook MR. MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells. PLoS One. 2018; 13(3):e0194868. PMID: 29566060.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    25. Sisk JM, Frieman MB, Machamer CE. Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors. J Gen Virol. 2018 05; 99(5):619-630. PMID: 29557770.
      Citations: 57     Fields:    Translation:AnimalsCells
    26. Dyall J, Gross R, Kindrachuk J, Johnson RF, Olinger GG, Hensley LE, Frieman MB, Jahrling PB. Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies. Drugs. 2017 Dec; 77(18):1935-1966. PMID: 29143192.
      Citations: 74     Fields:    Translation:HumansCells
    27. Venkataraman T, Coleman CM, Frieman MB. Overactive Epidermal Growth Factor Receptor Signaling Leads to Increased Fibrosis after Severe Acute Respiratory Syndrome Coronavirus Infection. J Virol. 2017 06 15; 91(12). PMID: 28404843.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    28. Venkataraman T, Frieman MB. The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis. Antiviral Res. 2017 07; 143:142-150. PMID: 28390872.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    29. Coleman CM, Venkataraman T, Liu YV, Glenn GM, Smith GE, Flyer DC, Frieman MB. MERS-CoV spike nanoparticles protect mice from MERS-CoV infection. Vaccine. 2017 03 14; 35(12):1586-1589. PMID: 28237499.
      Citations: 39     Fields:    Translation:AnimalsCells
    30. Wirblich C, Coleman CM, Kurup D, Abraham TS, Bernbaum JG, Jahrling PB, Hensley LE, Johnson RF, Frieman MB, Schnell MJ. One-Health: a Safe, Efficient, Dual-Use Vaccine for Humans and Animals against Middle East Respiratory Syndrome Coronavirus and Rabies Virus. J Virol. 2017 Jan 15; 91(2). PMID: 27807241.
      Citations: 36     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    31. Coleman CM, Sisk JM, Halasz G, Zhong J, Beck SE, Matthews KL, Venkataraman T, Rajagopalan S, Kyratsous CA, Frieman MB. CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome. J Virol. 2017 Jan 01; 91(1). PMID: 27795435.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    32. Coleman CM, Sisk JM, Mingo RM, Nelson EA, White JM, Frieman MB. Abelson Kinase Inhibitors Are Potent Inhibitors of Severe Acute Respiratory Syndrome Coronavirus and Middle East Respiratory Syndrome Coronavirus Fusion. J Virol. 2016 10 01; 90(19):8924-33. PMID: 27466418.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    33. Moser LA, Ramirez-Carvajal L, Puri V, Pauszek SJ, Matthews K, Dilley KA, Mullan C, McGraw J, Khayat M, Beeri K, Yee A, Dugan V, Heise MT, Frieman MB, Rodriguez LL, Bernard KA, Wentworth DE, Stockwell TB, Shabman RS. A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses. mSystems. 2016 May-Jun; 1(3). PMID: 27822536.
      Citations: 14     
    34. Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, Wang J, Nie W, Smith G, Hensley LE, Olinger GG, Kuhn JH, Holbrook MR, Johnson RF, Perlman S, Sullivan E, Frieman MB. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci Transl Med. 2016 Feb 17; 8(326):326ra21. PMID: 26888429.
      Citations: 56     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS. Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. PLoS Genet. 2015 Oct; 11(10):e1005504. PMID: 26452100.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    36. Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB. Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference. J Virol. 2015 Dec; 89(23):11820-33. PMID: 26378163.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    37. Sisk JM, Frieman MB. Screening of FDA-Approved Drugs for Treatment of Emerging Pathogens. ACS Infect Dis. 2015 Sep 11; 1(9):401-2. PMID: 27617922.
      Citations: 5     Fields:    
    38. Pascal KE, Coleman CM, Mujica AO, Kamat V, Badithe A, Fairhurst J, Hunt C, Strein J, Berrebi A, Sisk JM, Matthews KL, Babb R, Chen G, Lai KM, Huang TT, Olson W, Yancopoulos GD, Stahl N, Frieman MB, Kyratsous CA. Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection. Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28):8738-43. PMID: 26124093.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    39. Coleman CM, Frieman MB. Growth and Quantification of MERS-CoV Infection. Curr Protoc Microbiol. 2015 May 01; 37:15E.2.1-9. PMID: 26344219.
      Citations: 19     Fields:    Translation:AnimalsCells
    40. Kindrachuk J, Ork B, Hart BJ, Mazur S, Holbrook MR, Frieman MB, Traynor D, Johnson RF, Dyall J, Kuhn JH, Olinger GG, Hensley LE, Jahrling PB. Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis. Antimicrob Agents Chemother. 2015 Feb; 59(2):1088-99. PMID: 25487801.
      Citations: 162     Fields:    Translation:HumansCells
    41. Matthews K, Schäfer A, Pham A, Frieman M. The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity. Virol J. 2014 Dec 07; 11:209. PMID: 25481026.
      Citations: 26     Fields:    Translation:HumansCells
    42. Coleman CM, Frieman MB. Treating MERS-CoV during an outbreak. Lancet Infect Dis. 2014 Nov; 14(11):1030-1031. PMID: 25278219.
      Citations: 1     Fields:    Translation:HumansCells
    43. Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrob Agents Chemother. 2014 Aug; 58(8):4894-8. PMID: 24841268.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    44. Dyall J, Coleman CM, Hart BJ, Venkataraman T, Holbrook MR, Kindrachuk J, Johnson RF, Olinger GG, Jahrling PB, Laidlaw M, Johansen LM, Lear-Rooney CM, Glass PJ, Hensley LE, Frieman MB. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection. Antimicrob Agents Chemother. 2014 Aug; 58(8):4885-93. PMID: 24841273.
      Citations: 256     Fields:    Translation:HumansAnimalsCells
    45. Coleman CM, Liu YV, Mu H, Taylor JK, Massare M, Flyer DC, Smith GE, Frieman MB. Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine. 2014 May 30; 32(26):3169-3174. PMID: 24736006.
      Citations: 121     Fields:    Translation:AnimalsCells
    46. Coleman CM, Frieman MB. Coronaviruses: important emerging human pathogens. J Virol. 2014 May; 88(10):5209-12. PMID: 24600003.
      Citations: 83     Fields:    Translation:HumansCells
    47. Matthews KL, Coleman CM, van der Meer Y, Snijder EJ, Frieman MB. The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling. J Gen Virol. 2014 Apr; 95(Pt 4):874-882. PMID: 24443473.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    48. Hart BJ, Dyall J, Postnikova E, Zhou H, Kindrachuk J, Johnson RF, Olinger GG, Frieman MB, Holbrook MR, Jahrling PB, Hensley L. Interferon-ß and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays. J Gen Virol. 2014 Mar; 95(Pt 3):571-577. PMID: 24323636.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    49. Coleman CM, Matthews KL, Goicochea L, Frieman MB. Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus. J Gen Virol. 2014 Feb; 95(Pt 2):408-412. PMID: 24197535.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    50. Coleman CM, Frieman MB. Emergence of the Middle East respiratory syndrome coronavirus. PLoS Pathog. 2013; 9(9):e1003595. PMID: 24039577.
      Citations: 20     Fields:    Translation:HumansCells
    51. Page C, Goicochea L, Matthews K, Zhang Y, Klover P, Holtzman MJ, Hennighausen L, Frieman M. Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection. J Virol. 2012 Dec; 86(24):13334-49. PMID: 23015710.
      Citations: 55     Fields:    Translation:AnimalsCells
    52. Huynh J, Li S, Yount B, Smith A, Sturges L, Olsen JC, Nagel J, Johnson JB, Agnihothram S, Gates JE, Frieman MB, Baric RS, Donaldson EF. Evidence supporting a zoonotic origin of human coronavirus strain NL63. J Virol. 2012 Dec; 86(23):12816-25. PMID: 22993147.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    53. Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, Baric R, Engel DA. Yeast based small molecule screen for inhibitors of SARS-CoV. PLoS One. 2011; 6(12):e28479. PMID: 22164298.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    54. Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, Katze MG. Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection. mBio. 2011; 2(6). PMID: 22086488.
      Citations: 47     Fields:    Translation:AnimalsCells
    55. Frieman M, Yount B, Agnihothram S, Page C, Donaldson E, Roberts A, Vogel L, Woodruff B, Scorpio D, Subbarao K, Baric RS. Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J Virol. 2012 Jan; 86(2):884-97. PMID: 22072787.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    56. Peng X, Gralinski L, Armour CD, Ferris MT, Thomas MJ, Proll S, Bradel-Tretheway BG, Korth MJ, Castle JC, Biery MC, Bouzek HK, Haynor DR, Frieman MB, Heise M, Raymond CK, Baric RS, Katze MG. Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. mBio. 2010 Oct 26; 1(5). PMID: 20978541.
      Citations: 133     Fields:    Translation:AnimalsCells
    57. Donaldson EF, Haskew AN, Gates JE, Huynh J, Moore CJ, Frieman MB. Metagenomic analysis of the viromes of three North American bat species: viral diversity among different bat species that share a common habitat. J Virol. 2010 Dec; 84(24):13004-18. PMID: 20926577.
      Citations: 113     Fields:    Translation:AnimalsCells
    58. Zornetzer GA, Frieman MB, Rosenzweig E, Korth MJ, Page C, Baric RS, Katze MG. Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection. J Virol. 2010 Nov; 84(21):11297-309. PMID: 20702617.
      Citations: 24     Fields:    Translation:AnimalsCells
    59. Frieman MB, Chen J, Morrison TE, Whitmore A, Funkhouser W, Ward JM, Lamirande EW, Roberts A, Heise M, Subbarao K, Baric RS. SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. PLoS Pathog. 2010 Apr 08; 6(4):e1000849. PMID: 20386712.
      Citations: 84     Fields:    Translation:AnimalsCells
    60. Rockx B, Donaldson E, Frieman M, Sheahan T, Corti D, Lanzavecchia A, Baric RS. Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J Infect Dis. 2010 Mar 15; 201(6):946-55. PMID: 20144042.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    61. Freundt EC, Yu L, Goldsmith CS, Welsh S, Cheng A, Yount B, Liu W, Frieman MB, Buchholz UJ, Screaton GR, Lippincott-Schwartz J, Zaki SR, Xu XN, Baric RS, Subbarao K, Lenardo MJ. The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death. J Virol. 2010 Jan; 84(2):1097-109. PMID: 19889773.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    62. Rockx B, Baas T, Zornetzer GA, Haagmans B, Sheahan T, Frieman M, Dyer MD, Teal TH, Proll S, van den Brand J, Baric R, Katze MG. Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection. J Virol. 2009 Jul; 83(14):7062-74. PMID: 19420084.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    63. Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. J Virol. 2009 Jul; 83(13):6689-705. PMID: 19369340.
      Citations: 176     Fields:    Translation:HumansCells
    64. Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA. Novel influenza virus NS1 antagonists block replication and restore innate immune function. J Virol. 2009 Feb; 83(4):1881-91. PMID: 19052087.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    65. Frieman M, Baric R. Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation. Microbiol Mol Biol Rev. 2008 Dec; 72(4):672-85, Table of Contents. PMID: 19052324.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    66. Wathelet MG, Orr M, Frieman MB, Baric RS. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J Virol. 2007 Nov; 81(21):11620-33. PMID: 17715225.
      Citations: 176     Fields:    Translation:HumansAnimalsCells
    67. Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS. Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. J Virol. 2007 Sep; 81(18):9812-24. PMID: 17596301.
      Citations: 256     Fields:    Translation:HumansAnimalsCells
    68. Frieman M, Heise M, Baric R. SARS coronavirus and innate immunity. Virus Res. 2008 Apr; 133(1):101-12. PMID: 17451827.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    69. Kopecky-Bromberg SA, Martínez-Sobrido L, Frieman M, Baric RA, Palese P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J Virol. 2007 Jan; 81(2):548-57. PMID: 17108024.
      Citations: 335     Fields:    Translation:HumansCells
    70. Frieman MB, Yount B, Sims AC, Deming DJ, Morrison TE, Sparks J, Denison M, Heise M, Baric RS. SARS coronavirus accessory ORFs encode luxury functions. Adv Exp Med Biol. 2006; 581:149-52. PMID: 17037522.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    71. Baric RS, Sheahan T, Deming D, Donaldson E, Yount B, Sims AC, Roberts RS, Frieman M, Rockx B. SARS coronavirus vaccine development. Adv Exp Med Biol. 2006; 581:553-60. PMID: 17037597.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    72. Yount B, Roberts RS, Sims AC, Deming D, Frieman MB, Sparks J, Denison MR, Davis N, Baric RS. Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol. 2005 Dec; 79(23):14909-22. PMID: 16282490.
      Citations: 145     Fields:    Translation:AnimalsCells
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