Youhua Xie

InstitutionFudan University
AddressShanghai
China
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 28 Covid-19 publications, with a maximum of 4 publications in October 2020 and January 2021 and March 2021
    All Publications
    Bar chart showing 105 publications over 20 distinct years, with a maximum of 14 publications in 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. He X, Ding L, Cao K, Peng H, Gu C, Li Y, Li D, Dong L, Hong X, Wang X, Fu M, Qiu C, Zhu C, Zhang Z, Song S, Wang C, Jiang Z, Xie Y, Qi Z, Zhao C, Zhao P, Zhang X, Xu J. A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerg Microbes Infect. 2021 Dec; 10(1):1555-1573. PMID: 34304724.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    2. Zang J, Zhu Y, Zhou Y, Gu C, Yi Y, Wang S, Xu S, Hu G, Du S, Yin Y, Wang Y, Yang Y, Zhang X, Wang H, Yin F, Zhang C, Deng Q, Xie Y, Huang Z. Yeast-produced RBD-based recombinant protein vaccines elicit broadly neutralizing antibodies and durable protective immunity against SARS-CoV-2 infection. Cell Discov. 2021 Aug 18; 7(1):71. PMID: 34408130.
      Citations: 2     
    3. Zhou J, Xu W, Liu Z, Wang C, Xia S, Lan Q, Cai Y, Su S, Pu J, Xing L, Xie Y, Lu L, Jiang S, Wang Q. A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases. Acta Pharm Sin B. 2021 Aug 02. PMID: 34367893.
      Citations:    
    4. Xia S, Lan Q, Zhu Y, Wang C, Xu W, Li Y, Wang L, Jiao F, Zhou J, Hua C, Wang Q, Cai X, Wu Y, Gao J, Liu H, Sun G, Münch J, Kirchhoff F, Yuan Z, Xie Y, Sun F, Jiang S, Lu L. Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation. Signal Transduct Target Ther. 2021 07 29; 6(1):288. PMID: 34326308.
      Citations: 6     Translation:HumansAnimalsCells
    5. Ren W, Zhu Y, Wang Y, Shi H, Yu Y, Hu G, Feng F, Zhao X, Lan J, Wu J, Kenney DJ, Douam F, Tong Y, Zhong J, Xie Y, Wang X, Yuan Z, Zhou D, Zhang R, Ding Q. Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry. PLoS Pathog. 2021 03; 17(3):e1009392. PMID: 33760889.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    6. Liu Y, Hu G, Wang Y, Ren W, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Zhu Y, Cai X, Lan J, Guo J, Xie M, Dong L, Zhu Z, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z, Zhang R, Ding Q. Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2. Proc Natl Acad Sci U S A. 2021 03 23; 118(12). PMID: 33658332.
      Citations: 40     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    7. He CL, Huang LY, Wang K, Gu CJ, Hu J, Zhang GJ, Xu W, Xie YH, Tang N, Huang AL. Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products. Signal Transduct Target Ther. 2021 03 23; 6(1):131. PMID: 33758167.
      Citations: 8     Translation:HumansCells
    8. Han X, Wang Y, Li S, Hu C, Li T, Gu C, Wang K, Shen M, Wang J, Hu J, Wu R, Mu S, Gong F, Chen Q, Gao F, Huang J, Long Y, Luo F, Song S, Long S, Hao Y, Li L, Wu Y, Xu W, Cai X, Gao Q, Zhang G, He C, Deng K, Du L, Nai Y, Wang W, Xie Y, Qu D, Huang A, Tang N, Jin A. A Rapid and Efficient Screening System for Neutralizing Antibodies and Its Application for SARS-CoV-2. Front Immunol. 2021; 12:653189. PMID: 33828563.
      Citations: 8     Fields:    Translation:Humans
    9. Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Ding Q, Huang X, Chen H, Xu W, Xu W, Xie Y, Cai Q, Yuan Z, Zhang R. A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry. Nat Commun. 2021 02 11; 12(1):961. PMID: 33574281.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    10. Li F, Han M, Dai P, Xu W, He J, Tao X, Wu Y, Tong X, Xia X, Guo W, Zhou Y, Li Y, Zhu Y, Zhang X, Liu Z, Aji R, Cai X, Li Y, Qu D, Chen Y, Jiang S, Wang Q, Ji H, Xie Y, Sun Y, Lu L, Gao D. Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide. Nat Commun. 2021 02 08; 12(1):866. PMID: 33558541.
      Citations: 17     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Zhou Y, Liu Z, Li S, Xu W, Zhang Q, Silva IT, Li C, Wu Y, Jiang Q, Liu Z, Wang Q, Guo Y, Wu J, Gu C, Cai X, Qu D, Mayer CT, Wang X, Jiang S, Ying T, Yuan Z, Xie Y, Wen Y, Lu L, Wang Q. Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD. Cell Rep. 2021 02 02; 34(5):108699. PMID: 33485405.
      Citations: 25     Fields:    Translation:HumansCells
    12. Zhang C, Wang Y, Zhu Y, Liu C, Gu C, Xu S, Wang Y, Zhou Y, Wang Y, Han W, Hong X, Yang Y, Zhang X, Wang T, Xu C, Hong Q, Wang S, Zhao Q, Qiao W, Zang J, Kong L, Wang F, Wang H, Qu D, Lavillette D, Tang H, Deng Q, Xie Y, Cong Y, Huang Z. Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections. Nat Commun. 2021 01 11; 12(1):264. PMID: 33431876.
      Citations: 18     Fields:    Translation:AnimalsCells
    13. Wang S, Qiu Z, Hou Y, Deng X, Xu W, Zheng T, Wu P, Xie S, Bian W, Zhang C, Sun Z, Liu K, Shan C, Lin A, Jiang S, Xie Y, Zhou Q, Lu L, Huang J, Li X. AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells. Cell Res. 2021 02; 31(2):126-140. PMID: 33420426.
      Citations: 74     Fields:    Translation:HumansCells
    14. Jiang W, Wang J, Jiao S, Gu C, Xu W, Chen B, Wang R, Chen H, Xie Y, Wang A, Li G, Zeng D, Zhang J, Zhang M, Wang S, Wang M, Gui X. Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV. MAbs. 2021 Jan-Dec; 13(1):1953683. PMID: 34313527.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    15. Gu C, Wu Y, Guo H, Zhu Y, Xu W, Wang Y, Zhou Y, Sun Z, Cai X, Li Y, Liu J, Huang Z, Yuan Z, Zhang R, Deng Q, Qu D, Xie Y. Protoporphyrin IX and verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2. Sci Bull (Beijing). 2021 May 15; 66(9):925-936. PMID: 33318880.
      Citations: 7     
    16. Liu Z, Xu W, Xia S, Gu C, Wang X, Wang Q, Zhou J, Wu Y, Cai X, Qu D, Ying T, Xie Y, Lu L, Yuan Z, Jiang S. RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response. Signal Transduct Target Ther. 2020 11 27; 5(1):282. PMID: 33247109.
      Citations: 34     Translation:HumansAnimalsCellsPHPublic Health
    17. Guo L, Bi W, Wang X, Xu W, Yan R, Zhang Y, Zhao K, Li Y, Zhang M, Cai X, Jiang S, Xie Y, Zhou Q, Lu L, Dang B. Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. Cell Res. 2021 01; 31(1):98-100. PMID: 33177651.
      Citations: 24     Fields:    Translation:HumansCells
    18. Cai Y, Xu W, Gu C, Cai X, Qu D, Lu L, Xie Y, Jiang S. Griffithsin with A Broad-Spectrum Antiviral Activity by Binding Glycans in Viral Glycoprotein Exhibits Strong Synergistic Effect in Combination with A Pan-Coronavirus Fusion Inhibitor Targeting SARS-CoV-2 Spike S2 Subunit. Virol Sin. 2020 12; 35(6):857-860. PMID: 33052520.
      Citations: 11     Fields:    Translation:HumansCells
    19. Rao L, Xia S, Xu W, Tian R, Yu G, Gu C, Pan P, Meng QF, Cai X, Qu D, Lu L, Xie Y, Jiang S, Chen X. Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27141-27147. PMID: 33024017.
      Citations: 43     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    20. Zhao B, Ni C, Gao R, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J, Zhang R, Lin X. Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids. Protein Cell. 2020 10; 11(10):771-775. PMID: 32303993.
      Citations: 99     Fields:    Translation:HumansCellsPHPublic Health
    21. Wu F, Liu M, Wang A, Lu L, Wang Q, Gu C, Chen J, Wu Y, Xia S, Ling Y, Zhang Y, Xun J, Zhang R, Xie Y, Jiang S, Zhu T, Lu H, Wen Y, Huang J. Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China. JAMA Intern Med. 2020 10 01; 180(10):1356-1362. PMID: 32808970.
      Citations: 85     Fields:    Translation:HumansCellsPHPublic Health
    22. Zhang S, Liu Y, Wang X, Yang L, Li H, Wang Y, Liu M, Zhao X, Xie Y, Yang Y, Zhang S, Fan Z, Dong J, Yuan Z, Ding Z, Zhang Y, Hu L. SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19. J Hematol Oncol. 2020 09 04; 13(1):120. PMID: 32887634.
      Citations: 115     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. Zang J, Gu C, Zhou B, Zhang C, Yang Y, Xu S, Bai L, Zhang R, Deng Q, Yuan Z, Tang H, Qu D, Lavillette D, Xie Y, Huang Z. Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement. Cell Discov. 2020; 6:61. PMID: 32901211.
      Citations: 19     
    24. Sun Z, Cai X, Gu C, Zhang R, Han W, Qian Y, Wang Y, Xu W, Wu Y, Cheng X, Yuan Z, Xie Y, Qu D. Survival of SARS-COV-2 under liquid medium, dry filter paper and acidic conditions. Cell Discov. 2020; 6(1):57. PMID: 32821426.
      Citations: 2     
    25. Wang X, Xu W, Hu G, Xia S, Sun Z, Liu Z, Xie Y, Zhang R, Jiang S, Lu L. Retraction Note to: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion. Cell Mol Immunol. 2020 08; 17(8):894. PMID: 32651469.
      Citations: 17     Fields:    
    26. Wan J, Xing S, Ding L, Wang Y, Gu C, Wu Y, Rong B, Li C, Wang S, Chen K, He C, Zhu D, Yuan S, Qiu C, Zhao C, Nie L, Gao Z, Jiao J, Zhang X, Wang X, Ying T, Wang H, Xie Y, Lu Y, Xu J, Lan F. Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection. Cell Rep. 2020 07 21; 32(3):107918. PMID: 32668215.
      Citations: 59     Fields:    Translation:HumansCellsPHPublic Health
    27. Wu Y, Li C, Xia S, Tian X, Kong Y, Wang Z, Gu C, Zhang R, Tu C, Xie Y, Yang Z, Lu L, Jiang S, Ying T. Identification of Human Single-Domain Antibodies against SARS-CoV-2. Cell Host Microbe. 2020 06 10; 27(6):891-898.e5. PMID: 32413276.
      Citations: 89     Fields:    Translation:HumansCells
    28. Wang X, Xu W, Hu G, Xia S, Sun Z, Liu Z, Xie Y, Zhang R, Jiang S, Lu L. RETRACTED ARTICLE: SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion. Cell Mol Immunol. 2020 04 07. PMID: 32265513.
      Citations: 105     Fields:    
    29. Cheng A, Zhang W, Xie Y, Jiang W, Arnold E, Sarafianos SG, Ding J. Expression, purification, and characterization of SARS coronavirus RNA polymerase. Virology. 2005 May 10; 335(2):165-76. PMID: 15840516.
      Citations: 54     Fields:    Translation:Cells
    30. Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B. Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential. FEBS Lett. 2005 Apr 11; 579(10):2130-6. PMID: 15811330.
      Citations: 13     Fields:    Translation:HumansCells
    31. Luo H, Ye F, Sun T, Yue L, Peng S, Chen J, Li G, Du Y, Xie Y, Yang Y, Shen J, Wang Y, Shen X, Jiang H. In vitro biochemical and thermodynamic characterization of nucleocapsid protein of SARS. Biophys Chem. 2004 Dec 01; 112(1):15-25. PMID: 15501572.
      Citations: 16     Fields:    Translation:Cells
    32. Ren AX, Xie YH, Kong YY, Yang GZ, Zhang YZ, Wang Y, Wu XF. Expression, purification and sublocalization of SARS-CoV nucleocapsid protein in insect cells. Acta Biochim Biophys Sin (Shanghai). 2004 Nov; 36(11):754-8. PMID: 15514849.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    33. Wu XD, Shang B, Yang RF, Yu H, Ma ZH, Shen X, Ji YY, Lin Y, Wu YD, Lin GM, Tian L, Gan XQ, Yang S, Jiang WH, Dai EH, Wang XY, Jiang HL, Xie YH, Zhu XL, Pei G, Li L, Wu JR, Sun B. The spike protein of severe acute respiratory syndrome (SARS) is cleaved in virus infected Vero-E6 cells. Cell Res. 2004 Oct; 14(5):400-6. PMID: 15450134.
      Citations: 28     Fields:    Translation:AnimalsCells
    34. Zeng R, Yang RF, Shi MD, Jiang MR, Xie YH, Ruan HQ, Jiang XS, Shi L, Zhou H, Zhang L, Wu XD, Lin Y, Ji YY, Xiong L, Jin Y, Dai EH, Wang XY, Si BY, Wang J, Wang HX, Wang CE, Gan YH, Li YC, Cao JT, Zuo JP, Shan SF, Xie E, Chen SH, Jiang ZQ, Zhang X, Wang Y, Pei G, Sun B, Wu JR. Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients. J Mol Biol. 2004 Jul 30; 341(1):271-9. PMID: 15312778.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    35. Sun H, Luo H, Yu C, Sun T, Chen J, Peng S, Qin J, Shen J, Yang Y, Xie Y, Chen K, Wang Y, Shen X, Jiang H. Molecular cloning, expression, purification, and mass spectrometric characterization of 3C-like protease of SARS coronavirus. Protein Expr Purif. 2003 Dec; 32(2):302-8. PMID: 14965777.
      Citations: 13     Fields:    Translation:Cells
    36. Yu H, Yang Y, Zhang W, Xie YH, Qin J, Wang Y, Zheng HB, Zhao GP, Yang S, Jiang WH. [Expression and purification of recombinant SARS coronavirus spike protein]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Aug; 35(8):774-8. PMID: 12897976.
      Citations: 3     Fields:    Translation:Cells
    37. Lin Y, Shen X, Yang RF, Li YX, Ji YY, He YY, Shi MD, Lu W, Shi TL, Wang J, Wang HX, Jiang HL, Shen JH, Xie YH, Wang Y, Pei G, Shen BF, Wu JR, Sun B. Identification of an epitope of SARS-coronavirus nucleocapsid protein. Cell Res. 2003 Jun; 13(3):141-5. PMID: 12862314.
      Citations: 32     Fields:    Translation:HumansAnimalsCellsPHPublic Health
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