Yixuan J Hou

InstitutionUniversity of North Carolina at Chapel Hill
AddressChapel Hill
North Carolina
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 19 Covid-19 publications, with a maximum of 3 publications in November 2020 and January 2021
    All Publications
    Bar chart showing 49 publications over 10 distinct years, with a maximum of 10 publications in 2021
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Markmann AJ, Giallourou N, Bhowmik DR, Hou YJ, Lerner A, Martinez DR, Premkumar L, Root H, van Duin D, Napravnik S, Graham SD, Guerra Q, Raut R, Petropoulos CJ, Wrin T, Cornaby C, Schmitz J, Kuruc J, Weiss S, Park Y, Baric R, de Silva AM, Margolis DM, Bartelt LA. Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals. mSphere. 2021 08 25; 6(4):e0027521. PMID: 34431693.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    2. Zhang K, Zheludev IN, Hagey RJ, Haslecker R, Hou YJ, Kretsch R, Pintilie GD, Rangan R, Kladwang W, Li S, Wu MT, Pham EA, Bernardin-Souibgui C, Baric RS, Sheahan TP, D'Souza V, Glenn JS, Chiu W, Das R. Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome. Nat Struct Mol Biol. 2021 09; 28(9):747-754. PMID: 34426697.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    3. Sholukh AM, Fiore-Gartland A, Ford ES, Miner MD, Hou YJ, Tse LV, Kaiser H, Zhu H, Lu J, Madarampalli B, Park A, Lempp FA, St Germain R, Bossard EL, Kee JJ, Diem K, Stuart AB, Rupert PB, Brock C, Buerger M, Doll MK, Randhawa AK, Stamatatos L, Strong RK, McLaughlin C, Huang ML, Jerome KR, Baric RS, Montefiori D, Corey L. Evaluation of Cell-Based and Surrogate SARS-CoV-2 Neutralization Assays. J Clin Microbiol. 2021 09 20; 59(10):e0052721. PMID: 34288726.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    4. Niu X, Kong F, Hou YJ, Wang Q. Crucial mutation in the exoribonuclease domain of nsp14 of PEDV leads to high genetic instability during viral replication. Cell Biosci. 2021 Jun 07; 11(1):106. PMID: 34099051.
      Citations:    
    5. Voss WN, Hou YJ, Johnson NV, Delidakis G, Kim JE, Javanmardi K, Horton AP, Bartzoka F, Paresi CJ, Tanno Y, Chou CW, Abbasi SA, Pickens W, George K, Boutz DR, Towers DM, McDaniel JR, Billick D, Goike J, Rowe L, Batra D, Pohl J, Lee J, Gangappa S, Sambhara S, Gadush M, Wang N, Person MD, Iverson BL, Gollihar JD, Dye JM, Herbert AS, Finkelstein IJ, Baric RS, McLellan JS, Georgiou G, Lavinder JJ, Ippolito GC. Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science. 2021 06 04; 372(6546):1108-1112. PMID: 33947773.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    6. Adams LE, Dinnon KH, Hou YJ, Sheahan TP, Heise MT, Baric RS. Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication. mBio. 2021 03 16; 12(2). PMID: 33727353.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    7. Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, Glenn JS, Gralinski LE, Sheahan TP, Baric RS. Publisher Correction: A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. 2021 Feb; 590(7844):E22. PMID: 33469219.
      Citations: 1     Fields:    
    8. Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, Yang L, Hou Y, Scobey TD, Burton DR, Nemazee D, Dye JM, Voss JE, Gunn BM, McLellan JS, Baric RS, Gralinski LE, Walker LM. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science. 2021 02 19; 371(6531):823-829. PMID: 33495307.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    9. Dagotto G, Mercado NB, Martinez DR, Hou YJ, Nkolola JP, Carnahan RH, Crowe JE, Baric RS, Barouch DH. Comparison of Subgenomic and Total RNA in SARS-CoV-2 Challenged Rhesus Macaques. J Virol. 2021 Jan 20. PMID: 33472939.
      Citations: 13     Fields:    
    10. Niu X, Hou YJ, Jung K, Kong F, Saif LJ, Wang Q. Chimeric Porcine Deltacoronaviruses with Sparrow Coronavirus Spike Protein or the Receptor-Binding Domain Infect Pigs but Lose Virulence and Intestinal Tropism. Viruses. 2021 Jan 17; 13(1). PMID: 33477379.
      Citations: 1     Fields:    Translation:AnimalsCells
    11. Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, Weeks KM, Gladfelter AS. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Mol Cell. 2020 12 17; 80(6):1078-1091.e6. PMID: 33290746.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    12. Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Graham R, Edwards CE, Tse LV, Okuda K, Markmann AJ, Bartelt L, de Silva A, Margolis DM, Boucher RC, Randell SH, Suzuki T, Gralinski LE, Kawaoka Y, Baric RS. SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. Science. 2020 12 18; 370(6523):1464-1468. PMID: 33184236.
      Citations: 247     Fields:    Translation:HumansAnimals
    13. Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M, Blancas-Mejia LM, Yen HL, Silva DA. De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2. Science. 2020 12 04; 370(6521):1208-1214. PMID: 33154107.
      Citations: 44     Fields:    Translation:AnimalsCells
    14. Edwards CE, Yount BL, Graham RL, Leist SR, Hou YJ, Dinnon KH, Sims AC, Swanstrom J, Gully K, Scobey TD, Cooley MR, Currie CG, Randell SH, Baric RS. Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection. Proc Natl Acad Sci U S A. 2020 10 27; 117(43):26915-26925. PMID: 33046644.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    15. Leist SR, Dinnon KH, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS. A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell. 2020 11 12; 183(4):1070-1085.e12. PMID: 33031744.
      Citations: 88     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Dinnon KH, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, Glenn JS, Gralinski LE, Sheahan TP, Baric RS. A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures. Nature. 2020 10; 586(7830):560-566. PMID: 32854108.
      Citations: 156     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    17. Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, Kashentseva E, McCune BT, Bailey AL, Zhao H, VanBlargan LA, Dai YN, Ma M, Adams LJ, Shrihari S, Danis JE, Gralinski LE, Hou YJ, Schäfer A, Kim AS, Keeler SP, Weiskopf D, Baric RS, Holtzman MJ, Fremont DH, Curiel DT, Diamond MS. A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. Cell. 2020 10 01; 183(1):169-184.e13. PMID: 32931734.
      Citations: 105     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Premkumar L, Segovia-Chumbez B, Jadi R, Martinez DR, Raut R, Markmann A, Cornaby C, Bartelt L, Weiss S, Park Y, Edwards CE, Weimer E, Scherer EM, Rouphael N, Edupuganti S, Weiskopf D, Tse LV, Hou YJ, Margolis D, Sette A, Collins MH, Schmitz J, Baric RS, de Silva AM. The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients. Sci Immunol. 2020 06 11; 5(48). PMID: 32527802.
      Citations: 245     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    19. Citations: 376     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    20. Hou Y, Wang Q. Emerging Highly Virulent Porcine Epidemic Diarrhea Virus: Molecular Mechanisms of Attenuation and Rational Design of Live Attenuated Vaccines. Int J Mol Sci. 2019 Nov 04; 20(21). PMID: 31689903.
      Citations: 10     Fields:    Translation:AnimalsCells
    21. Pandey K, Zhong S, Diel DG, Hou Y, Wang Q, Nelson E, Wang X. GTPase-activating protein-binding protein 1 (G3BP1) plays an antiviral role against porcine epidemic diarrhea virus. Vet Microbiol. 2019 Sep; 236:108392. PMID: 31500725.
      Citations: 7     Fields:    Translation:AnimalsCells
    22. Hou Y, Ke H, Kim J, Yoo D, Su Y, Boley P, Chepngeno J, Vlasova AN, Saif LJ, Wang Q. Engineering a Live Attenuated Porcine Epidemic Diarrhea Virus Vaccine Candidate via Inactivation of the Viral 2'-O-Methyltransferase and the Endocytosis Signal of the Spike Protein. J Virol. 2019 08 01; 93(15). PMID: 31118255.
      Citations: 11     Fields:    Translation:AnimalsCells
    23. Chen P, Wang K, Hou Y, Li H, Li X, Yu L, Jiang Y, Gao F, Tong W, Yu H, Yang Z, Tong G, Zhou Y. Genetic evolution analysis and pathogenicity assessment of porcine epidemic diarrhea virus strains circulating in part of China during 2011-2017. Infect Genet Evol. 2019 04; 69:153-165. PMID: 30677534.
      Citations: 15     Fields:    Translation:AnimalsCells
    24. Lin CM, Ghimire S, Hou Y, Boley P, Langel SN, Vlasova AN, Saif LJ, Wang Q. Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigs. BMC Vet Res. 2019 Jan 11; 15(1):26. PMID: 30634958.
      Citations: 11     Fields:    Translation:AnimalsCells
    25. Hou Y, Meulia T, Gao X, Saif LJ, Wang Q. Deletion of both the Tyrosine-Based Endocytosis Signal and the Endoplasmic Reticulum Retrieval Signal in the Cytoplasmic Tail of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Pigs. J Virol. 2019 01 15; 93(2). PMID: 30404797.
      Citations: 19     Fields:    Translation:AnimalsCells
    26. Su Y, Hou Y, Wang Q. The enhanced replication of an S-intact PEDV during coinfection with an S1 NTD-del PEDV in piglets. Vet Microbiol. 2019 Jan; 228:202-212. PMID: 30593369.
      Citations: 6     Fields:    Translation:AnimalsCells
    27. Su Y, Hou Y, Prarat M, Zhang Y, Wang Q. New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States, 2016-2017. Arch Virol. 2018 Sep; 163(9):2485-2489. PMID: 29789941.
      Citations: 11     Fields:    Translation:AnimalsCells
    28. Hou Y, Lin CM, Yokoyama M, Yount BL, Marthaler D, Douglas AL, Ghimire S, Qin Y, Baric RS, Saif LJ, Wang Q. Deletion of a 197-Amino-Acid Region in the N-Terminal Domain of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Piglets. J Virol. 2017 07 15; 91(14). PMID: 28490591.
      Citations: 23     Fields:    Translation:AnimalsCells
    29. Lin CM, Hou Y, Marthaler DG, Gao X, Liu X, Zheng L, Saif LJ, Wang Q. Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage. Vet Microbiol. 2017 Mar; 201:62-71. PMID: 28284624.
      Citations: 18     Fields:    Translation:AnimalsCells
    30. Beall A, Yount B, Lin CM, Hou Y, Wang Q, Saif L, Saif L, Baric R. Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A. mBio. 2016 Jan 05; 7(1):e01451-15. PMID: 26733065.
      Citations: 30     Fields:    Translation:AnimalsCells
    31. Hou Y, Yue X, Cai X, Wang S, Liu Y, Yuan C, Cui L, Hua X, Yang Z. Complete genome of transmissible gastroenteritis virus AYU strain isolated in Shanghai, China. J Virol. 2012 Nov; 86(21):11935. PMID: 23043168.
      Citations: 5     Fields:    Translation:AnimalsCells
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