Kevin M Weeks

InstitutionThe University of North Carolina
AddressNorth Carolina
United States
vCardDownload vCard
    Publication Timeline
    COVID-19 publications
    Bar chart showing 1 Covid-19 publications, with a maximum of 1 publications in November 2020
    All Publications
    Bar chart showing 110 publications over 19 distinct years, with a maximum of 11 publications in 2015
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
    Sort By:     Newest   |   Oldest   |   Most Cited   |   Most Discussed
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, Fritch EJ, Hou YJ, Ekena J, Weidmann CA, Theesfeld CL, Kellis M, Troyanskaya OG, Baric RS, Sheahan TP, Weeks KM, Gladfelter AS. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Mol Cell. 2020 12 17; 80(6):1078-1091.e6. PMID: 33290746.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    2. Giannetti CA, Busan S, Weidmann CA, Weeks KM. SHAPE Probing Reveals Human rRNAs Are Largely Unfolded in Solution. Biochemistry. 2019 08 06; 58(31):3377-3385. PMID: 31305988.
      Citations: 3     Fields:    Translation:HumansCells
    3. Dethoff EA, Weeks KM. Effects of Refolding on Large-Scale RNA Structure. Biochemistry. 2019 07 16; 58(28):3069-3077. PMID: 31268687.
      Citations: 2     Fields:    Translation:Cells
    4. Busan S, Weidmann CA, Sengupta A, Weeks KM. Guidelines for SHAPE Reagent Choice and Detection Strategy for RNA Structure Probing Studies. Biochemistry. 2019 06 11; 58(23):2655-2664. PMID: 31117385.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    5. Dethoff EA, Boerneke MA, Gokhale NS, Muhire BM, Martin DP, Sacco MT, McFadden MJ, Weinstein JB, Messer WB, Horner SM, Weeks KM. Pervasive tertiary structure in the dengue virus RNA genome. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):11513-11518. PMID: 30341219.
      Citations: 36     Fields:    Translation:Cells
    6. Kirk JM, Kim SO, Inoue K, Smola MJ, Lee DM, Schertzer MD, Wooten JS, Baker AR, Sprague D, Collins DW, Horning CR, Wang S, Chen Q, Weeks KM, Mucha PJ, Calabrese JM. Functional classification of long non-coding RNAs by k-mer content. Nat Genet. 2018 10; 50(10):1474-1482. PMID: 30224646.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    7. Warner KD, Hajdin CE, Weeks KM. Principles for targeting RNA with drug-like small molecules. Nat Rev Drug Discov. 2018 08; 17(8):547-558. PMID: 29977051.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    8. Mustoe AM, Corley M, Laederach A, Weeks KM. Messenger RNA Structure Regulates Translation Initiation: A Mechanism Exploited from Bacteria to Humans. Biochemistry. 2018 07 03; 57(26):3537-3539. PMID: 29894169.
      Citations: 16     Fields:    Translation:HumansCells
    9. Langdon EM, Qiu Y, Ghanbari Niaki A, McLaughlin GA, Weidmann CA, Gerbich TM, Smith JA, Crutchley JM, Termini CM, Weeks KM, Myong S, Gladfelter AS. mRNA structure determines specificity of a polyQ-driven phase separation. Science. 2018 05 25; 360(6391):922-927. PMID: 29650703.
      Citations: 145     Fields:    Translation:Cells
    10. Williams B, Zhao B, Tandon A, Ding F, Weeks KM, Zhang Q, Dokholyan NV. Structure modeling of RNA using sparse NMR constraints. Nucleic Acids Res. 2017 Dec 15; 45(22):12638-12647. PMID: 29165648.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    11. Liu Y, Chen J, Nikolaitchik OA, Desimmie BA, Busan S, Pathak VK, Weeks KM, Hu WS. The roles of five conserved lentiviral RNA structures in HIV-1 replication. Virology. 2018 01 15; 514:1-8. PMID: 29128752.
      Citations: 4     Fields:    Translation:HumansCells
    12. Busan S, Weeks KM. Accurate detection of chemical modifications in RNA by mutational profiling (MaP) with ShapeMapper 2. RNA. 2018 02; 24(2):143-148. PMID: 29114018.
      Citations: 34     Fields:    Translation:Cells
    13. Corley M, Solem A, Phillips G, Lackey L, Ziehr B, Vincent HA, Mustoe AM, Ramos SBV, Weeks KM, Moorman NJ, Laederach A. An RNA structure-mediated, posttranscriptional model of human a-1-antitrypsin expression. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):E10244-E10253. PMID: 29109288.
      Citations: 18     Fields:    Translation:HumansCells
    14. Busan S, Weeks KM. Visualization of RNA structure models within the Integrative Genomics Viewer. RNA. 2017 07; 23(7):1012-1018. PMID: 28428329.
      Citations: 12     Fields:    Translation:Cells
    15. Larman BC, Dethoff EA, Weeks KM. Packaged and Free Satellite Tobacco Mosaic Virus (STMV) RNA Genomes Adopt Distinct Conformational States. Biochemistry. 2017 04 25; 56(16):2175-2183. PMID: 28332826.
      Citations: 9     Fields:    Translation:Cells
    16. Krokhotin A, Mustoe AM, Weeks KM, Dokholyan NV. Direct identification of base-paired RNA nucleotides by correlated chemical probing. RNA. 2017 01; 23(1):6-13. PMID: 27803152.
      Citations: 10     Fields:    Translation:Cells
    17. Smola MJ, Christy TW, Inoue K, Nicholson CO, Friedersdorf M, Keene JD, Lee DM, Calabrese JM, Weeks KM. SHAPE reveals transcript-wide interactions, complex structural domains, and protein interactions across the Xist lncRNA in living cells. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10322-7. PMID: 27578869.
      Citations: 92     Fields:    Translation:AnimalsCells
    18. Weidmann CA, Mustoe AM, Weeks KM. Direct Duplex Detection: An Emerging Tool in the RNA Structure Analysis Toolbox. Trends Biochem Sci. 2016 09; 41(9):734-736. PMID: 27427309.
      Citations: 9     Fields:    Translation:Cells
    19. Smola MJ, Calabrese JM, Weeks KM. Detection of RNA-Protein Interactions in Living Cells with SHAPE. Biochemistry. 2015 Nov 24; 54(46):6867-75. PMID: 26544910.
      Citations: 58     Fields:    Translation:AnimalsCells
    20. Lu YF, Mauger DM, Goldstein DB, Urban TJ, Weeks KM, Bradrick SS. IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance. Sci Rep. 2015 Nov 04; 5:16037. PMID: 26531896.
      Citations: 20     Fields:    Translation:HumansCells
    21. Tyrrell J, Weeks KM, Pielak GJ. Challenge of mimicking the influences of the cellular environment on RNA structure by PEG-induced macromolecular crowding. Biochemistry. 2015 Oct 27; 54(42):6447-53. PMID: 26430778.
      Citations: 22     Fields:    Translation:Cells
    22. Smola MJ, Rice GM, Busan S, Siegfried NA, Weeks KM. Selective 2'-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis. Nat Protoc. 2015 Nov; 10(11):1643-69. PMID: 26426499.
      Citations: 96     Fields:    Translation:Cells
    23. Weeks KM. Review toward all RNA structures, concisely. Biopolymers. 2015 Aug; 103(8):438-48. PMID: 25546503.
      Citations: 15     Fields:    Translation:Cells
    24. Kutchko KM, Sanders W, Ziehr B, Phillips G, Solem A, Halvorsen M, Weeks KM, Moorman N, Laederach A. Multiple conformations are a conserved and regulatory feature of the RB1 5' UTR. RNA. 2015 Jul; 21(7):1274-85. PMID: 25999316.
      Citations: 36     Fields:    Translation:HumansCells
    25. Lavender CA, Lorenz R, Zhang G, Tamayo R, Hofacker IL, Weeks KM. Model-Free RNA Sequence and Structure Alignment Informed by SHAPE Probing Reveals a Conserved Alternate Secondary Structure for 16S rRNA. PLoS Comput Biol. 2015 May; 11(5):e1004126. PMID: 25992778.
      Citations: 24     Fields:    Translation:Cells
    26. Lavender CA, Gorelick RJ, Weeks KM. Structure-Based Alignment and Consensus Secondary Structures for Three HIV-Related RNA Genomes. PLoS Comput Biol. 2015 May; 11(5):e1004230. PMID: 25992893.
      Citations: 22     Fields:    Translation:AnimalsCells
    27. Weeks KM. RNA clubs. RNA. 2015 Apr; 21(4):760-1. PMID: 25780225.
      Citations:    Fields:    Translation:Cells
    28. Mauger DM, Golden M, Yamane D, Williford S, Lemon SM, Martin DP, Weeks KM. Functionally conserved architecture of hepatitis C virus RNA genomes. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3692-7. PMID: 25775547.
      Citations: 59     Fields:    Translation:Cells
    29. McGinnis JL, Liu Q, Lavender CA, Devaraj A, McClory SP, Fredrick K, Weeks KM. In-cell SHAPE reveals that free 30S ribosome subunits are in the inactive state. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2425-30. PMID: 25675474.
      Citations: 33     Fields:    Translation:Cells
    30. Homan PJ, Tandon A, Rice GM, Ding F, Dokholyan NV, Weeks KM. RNA tertiary structure analysis by 2'-hydroxyl molecular interference. Biochemistry. 2014 Nov 04; 53(43):6825-33. PMID: 25341083.
      Citations: 8     Fields:    Translation:AnimalsCells
    31. Homan PJ, Favorov OV, Lavender CA, Kursun O, Ge X, Busan S, Dokholyan NV, Weeks KM. Single-molecule correlated chemical probing of RNA. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13858-63. PMID: 25205807.
      Citations: 47     Fields:    Translation:AnimalsCells
    32. Siegfried NA, Busan S, Rice GM, Nelson JA, Weeks KM. RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP). Nat Methods. 2014 Sep; 11(9):959-65. PMID: 25028896.
      Citations: 193     Fields:    Translation:Cells
    33. McGinnis JL, Weeks KM. Ribosome RNA assembly intermediates visualized in living cells. Biochemistry. 2014 May 20; 53(19):3237-47. PMID: 24818530.
      Citations: 21     Fields:    Translation:Cells
    34. Warner KD, Homan P, Weeks KM, Smith AG, Abell C, Ferré-D'Amaré AR. Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically. Chem Biol. 2014 May 22; 21(5):591-5. PMID: 24768306.
      Citations: 29     Fields:    Translation:Cells
    35. Rice GM, Leonard CW, Weeks KM. RNA secondary structure modeling at consistent high accuracy using differential SHAPE. RNA. 2014 Jun; 20(6):846-54. PMID: 24742934.
      Citations: 43     Fields:    Translation:Cells
    36. Grohman JK, Gorelick RJ, Kottegoda S, Allbritton NL, Rein A, Weeks KM. An immature retroviral RNA genome resembles a kinetically trapped intermediate state. J Virol. 2014 Jun; 88(11):6061-8. PMID: 24623442.
      Citations: 8     Fields:    Translation:Cells
    37. Rice GM, Busan S, Karabiber F, Favorov OV, Weeks KM. SHAPE analysis of small RNAs and riboswitches. Methods Enzymol. 2014; 549:165-87. PMID: 25432749.
      Citations: 7     Fields:    Translation:Cells
    38. Tyrrell J, McGinnis JL, Weeks KM, Pielak GJ. The cellular environment stabilizes adenine riboswitch RNA structure. Biochemistry. 2013 Dec 03; 52(48):8777-85. PMID: 24215455.
      Citations: 61     Fields:    Translation:Cells
    39. Busan S, Weeks KM. Role of context in RNA structure: flanking sequences reconfigure CAG motif folding in huntingtin exon 1 transcripts. Biochemistry. 2013 Nov 19; 52(46):8219-25. PMID: 24199621.
      Citations: 14     Fields:    Translation:HumansCells
    40. Archer EJ, Simpson MA, Watts NJ, O'Kane R, Wang B, Erie DA, McPherson A, Weeks KM. Long-range architecture in a viral RNA genome. Biochemistry. 2013 May 07; 52(18):3182-90. PMID: 23614526.
      Citations: 20     Fields:    Translation:Cells
    41. Pollom E, Dang KK, Potter EL, Gorelick RJ, Burch CL, Weeks KM, Swanstrom R. Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs. PLoS Pathog. 2013; 9(4):e1003294. PMID: 23593004.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    42. Hajdin CE, Bellaousov S, Huggins W, Leonard CW, Mathews DH, Weeks KM. Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5498-503. PMID: 23503844.
      Citations: 147     Fields:    Translation:Cells
    43. Grohman JK, Gorelick RJ, Lickwar CR, Lieb JD, Bower BD, Znosko BM, Weeks KM. A guanosine-centric mechanism for RNA chaperone function. Science. 2013 Apr 12; 340(6129):190-5. PMID: 23470731.
      Citations: 27     Fields:    Translation:Cells
    44. Ramachandran S, Ding F, Weeks KM, Dokholyan NV. Statistical analysis of SHAPE-directed RNA secondary structure modeling. Biochemistry. 2013 Jan 29; 52(4):596-9. PMID: 23286327.
      Citations: 9     Fields:    Translation:Cells
    45. Leonard CW, Hajdin CE, Karabiber F, Mathews DH, Favorov OV, Dokholyan NV, Weeks KM. Principles for understanding the accuracy of SHAPE-directed RNA structure modeling. Biochemistry. 2013 Jan 29; 52(4):588-95. PMID: 23316814.
      Citations: 27     Fields:    Translation:Cells
    46. Karabiber F, McGinnis JL, Favorov OV, Weeks KM. QuShape: rapid, accurate, and best-practices quantification of nucleic acid probing information, resolved by capillary electrophoresis. RNA. 2013 Jan; 19(1):63-73. PMID: 23188808.
      Citations: 95     Fields:    Translation:HumansCells
    47. Steen KA, Rice GM, Weeks KM. Fingerprinting noncanonical and tertiary RNA structures by differential SHAPE reactivity. J Am Chem Soc. 2012 Aug 15; 134(32):13160-3. PMID: 22852530.
      Citations: 44     Fields:    Translation:Cells
    48. Ding F, Lavender CA, Weeks KM, Dokholyan NV. Three-dimensional RNA structure refinement by hydroxyl radical probing. Nat Methods. 2012 Apr 15; 9(6):603-8. PMID: 22504587.
      Citations: 36     Fields:    Translation:Cells
    49. McGinnis JL, Dunkle JA, Cate JH, Weeks KM. The mechanisms of RNA SHAPE chemistry. J Am Chem Soc. 2012 Apr 18; 134(15):6617-24. PMID: 22475022.
      Citations: 80     Fields:    Translation:Cells
    50. Low JT, Knoepfel SA, Watts JM, ter Brake O, Berkhout B, Weeks KM. SHAPE-directed discovery of potent shRNA inhibitors of HIV-1. Mol Ther. 2012 Apr; 20(4):820-8. PMID: 22314289.
      Citations: 25     Fields:    Translation:HumansCells
    51. Grohman JK, Kottegoda S, Gorelick RJ, Allbritton NL, Weeks KM. Femtomole SHAPE reveals regulatory structures in the authentic XMRV RNA genome. J Am Chem Soc. 2011 Dec 21; 133(50):20326-34. PMID: 22126209.
      Citations: 10     Fields:    Translation:Cells
    52. Steen KA, Siegfried NA, Weeks KM. Selective 2'-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNA. Nat Protoc. 2011 Oct 06; 6(11):1683-94. PMID: 21979276.
      Citations: 16     Fields:    Translation:Cells
    53. Weeks KM. RNA structure probing dash seq. Proc Natl Acad Sci U S A. 2011 Jul 05; 108(27):10933-4. PMID: 21700884.
      Citations: 7     Fields:    Translation:Cells
    54. Weeks KM, Mauger DM. Exploring RNA structural codes with SHAPE chemistry. Acc Chem Res. 2011 Dec 20; 44(12):1280-91. PMID: 21615079.
      Citations: 69     Fields:    Translation:Cells
    55. Rocca-Serra P, Bellaousov S, Birmingham A, Chen C, Cordero P, Das R, Davis-Neulander L, Duncan CD, Halvorsen M, Knight R, Leontis NB, Mathews DH, Ritz J, Stombaugh J, Weeks KM, Zirbel CL, Laederach A. Sharing and archiving nucleic acid structure mapping data. RNA. 2011 Jul; 17(7):1204-12. PMID: 21610212.
      Citations: 20     Fields:    Translation:HumansCells
    56. Mauger DM, Weeks KM. Toward global RNA structure analysis. Nat Biotechnol. 2010 Nov; 28(11):1178-9. PMID: 21057487.
      Citations: 11     Fields:    Translation:AnimalsCells
    57. Gherghe C, Lombo T, Leonard CW, Datta SA, Bess JW, Gorelick RJ, Rein A, Weeks KM. Definition of a high-affinity Gag recognition structure mediating packaging of a retroviral RNA genome. Proc Natl Acad Sci U S A. 2010 Nov 09; 107(45):19248-53. PMID: 20974908.
      Citations: 47     Fields:    Translation:AnimalsCells
    58. Simon-Loriere E, Martin DP, Weeks KM, Negroni M. RNA structures facilitate recombination-mediated gene swapping in HIV-1. J Virol. 2010 Dec; 84(24):12675-82. PMID: 20881047.
      Citations: 24     Fields:    Translation:HumansCells
    59. Steen KA, Malhotra A, Weeks KM. Selective 2'-hydroxyl acylation analyzed by protection from exoribonuclease. J Am Chem Soc. 2010 Jul 28; 132(29):9940-3. PMID: 20597503.
      Citations: 24     Fields:    Translation:Cells
    60. Duncan CD, Weeks KM. Nonhierarchical ribonucleoprotein assembly suggests a strain-propagation model for protein-facilitated RNA folding. Biochemistry. 2010 Jul 06; 49(26):5418-25. PMID: 20533823.
      Citations: 20     Fields:    Translation:AnimalsCells
    61. Lavender CA, Ding F, Dokholyan NV, Weeks KM. Robust and generic RNA modeling using inferred constraints: a structure for the hepatitis C virus IRES pseudoknot domain. Biochemistry. 2010 Jun 22; 49(24):4931-3. PMID: 20545364.
      Citations: 20     Fields:    Translation:Cells
    62. Low JT, Weeks KM. SHAPE-directed RNA secondary structure prediction. Methods. 2010 Oct; 52(2):150-8. PMID: 20554050.
      Citations: 123     Fields:    Translation:Cells
    63. Hajdin CE, Ding F, Dokholyan NV, Weeks KM. On the significance of an RNA tertiary structure prediction. RNA. 2010 Jul; 16(7):1340-9. PMID: 20498460.
      Citations: 48     Fields:    Translation:Cells
    64. Weeks KM. Advances in RNA structure analysis by chemical probing. Curr Opin Struct Biol. 2010 Jun; 20(3):295-304. PMID: 20447823.
      Citations: 121     Fields:    Translation:AnimalsCells
    65. Duncan CD, Weeks KM. The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. PLoS One. 2010 Feb 01; 5(2):e8983. PMID: 20126554.
      Citations: 9     Fields:    Translation:Cells
    66. Gherghe C, Leonard CW, Gorelick RJ, Weeks KM. Secondary structure of the mature ex virio Moloney murine leukemia virus genomic RNA dimerization domain. J Virol. 2010 Jan; 84(2):898-906. PMID: 19889760.
      Citations: 21     Fields:    Translation:AnimalsCells
    67. Mortimer SA, Weeks KM. Time-resolved RNA SHAPE chemistry: quantitative RNA structure analysis in one-second snapshots and at single-nucleotide resolution. Nat Protoc. 2009; 4(10):1413-21. PMID: 19745823.
      Citations: 56     Fields:    Translation:Cells
    68. Mortimer SA, Weeks KM. C2'-endo nucleotides as molecular timers suggested by the folding of an RNA domain. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15622-7. PMID: 19717440.
      Citations: 30     Fields:    Translation:Cells
    69. Watts JM, Dang KK, Gorelick RJ, Leonard CW, Bess JW, Swanstrom R, Burch CL, Weeks KM. Architecture and secondary structure of an entire HIV-1 RNA genome. Nature. 2009 Aug 06; 460(7256):711-6. PMID: 19661910.
      Citations: 428     Fields:    Translation:Cells
    70. Wilkinson KA, Vasa SM, Deigan KE, Mortimer SA, Giddings MC, Weeks KM. Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA. RNA. 2009 Jul; 15(7):1314-21. PMID: 19458034.
      Citations: 50     Fields:    Translation:Cells
    71. Mortimer SA, Johnson JS, Weeks KM. Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine. Biochemistry. 2009 Mar 17; 48(10):2109-14. PMID: 19226117.
      Citations: 9     Fields:    Translation:Cells
    72. Gherghe CM, Leonard CW, Ding F, Dokholyan NV, Weeks KM. Native-like RNA tertiary structures using a sequence-encoded cleavage agent and refinement by discrete molecular dynamics. J Am Chem Soc. 2009 Feb 25; 131(7):2541-6. PMID: 19193004.
      Citations: 36     Fields:    Translation:Cells
    73. McGinnis JL, Duncan CD, Weeks KM. High-throughput SHAPE and hydroxyl radical analysis of RNA structure and ribonucleoprotein assembly. Methods Enzymol. 2009; 468:67-89. PMID: 20946765.
      Citations: 53     Fields:    Translation:Cells
    74. Deigan KE, Li TW, Mathews DH, Weeks KM. Accurate SHAPE-directed RNA structure determination. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):97-102. PMID: 19109441.
      Citations: 336     Fields:    Translation:Cells
    75. Mortimer SA, Weeks KM. Time-resolved RNA SHAPE chemistry. J Am Chem Soc. 2008 Dec 03; 130(48):16178-80. PMID: 18998638.
      Citations: 45     Fields:    Translation:Cells
    76. Maity TS, Fried HM, Weeks KM. Anti-cooperative assembly of the SRP19 and SRP68/72 components of the signal recognition particle. Biochem J. 2008 Nov 01; 415(3):429-37. PMID: 18564060.
      Citations: 5     Fields:    Translation:HumansCells
    77. Vasa SM, Guex N, Wilkinson KA, Weeks KM, Giddings MC. ShapeFinder: a software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis. RNA. 2008 Oct; 14(10):1979-90. PMID: 18772246.
      Citations: 139     Fields:    Translation:Cells
    78. Gherghe CM, Shajani Z, Wilkinson KA, Varani G, Weeks KM. Strong correlation between SHAPE chemistry and the generalized NMR order parameter (S2) in RNA. J Am Chem Soc. 2008 Sep 17; 130(37):12244-5. PMID: 18710236.
      Citations: 62     Fields:    Translation:Cells
    79. Duncan CD, Weeks KM. SHAPE analysis of long-range interactions reveals extensive and thermodynamically preferred misfolding in a fragile group I intron RNA. Biochemistry. 2008 Aug 19; 47(33):8504-13. PMID: 18642882.
      Citations: 29     Fields:    Translation:Cells
    80. Gherghe CM, Mortimer SA, Krahn JM, Thompson NL, Weeks KM. Slow conformational dynamics at C2'-endo nucleotides in RNA. J Am Chem Soc. 2008 Jul 16; 130(28):8884-5. PMID: 18558680.
      Citations: 33     Fields:    Translation:Cells
    81. Wilkinson KA, Gorelick RJ, Vasa SM, Guex N, Rein A, Mathews DH, Giddings MC, Weeks KM. High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states. PLoS Biol. 2008 Apr 29; 6(4):e96. PMID: 18447581.
      Citations: 235     Fields:    Translation:HumansCells
    82. Jones CN, Wilkinson KA, Hung KT, Weeks KM, Spremulli LL. Lack of secondary structure characterizes the 5' ends of mammalian mitochondrial mRNAs. RNA. 2008 May; 14(5):862-71. PMID: 18367717.
      Citations: 24     Fields:    Translation:AnimalsCells
    83. Wang B, Wilkinson KA, Weeks KM. Complex ligand-induced conformational changes in tRNA(Asp) revealed by single-nucleotide resolution SHAPE chemistry. Biochemistry. 2008 Mar 18; 47(11):3454-61. PMID: 18290632.
      Citations: 30     Fields:    Translation:AnimalsCells
    84. Maity TS, Weeks KM. A threefold RNA-protein interface in the signal recognition particle gates native complex assembly. J Mol Biol. 2007 Jun 01; 369(2):512-24. PMID: 17434535.
      Citations: 7     Fields:    Translation:HumansCells
    85. Mortimer SA, Weeks KM. A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry. J Am Chem Soc. 2007 Apr 11; 129(14):4144-5. PMID: 17367143.
      Citations: 186     Fields:    Translation:Cells
    86. Maity TS, Leonard CW, Rose MA, Fried HM, Weeks KM. Compartmentalization directs assembly of the signal recognition particle. Biochemistry. 2006 Dec 19; 45(50):14955-64. PMID: 17154533.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    87. Badorrek CS, Weeks KM. Architecture of a gamma retroviral genomic RNA dimer. Biochemistry. 2006 Oct 24; 45(42):12664-72. PMID: 17042483.
      Citations: 31     Fields:    Translation:Cells
    88. Gherghe C, Weeks KM. The SL1-SL2 (stem-loop) domain is the primary determinant for stability of the gamma retroviral genomic RNA dimer. J Biol Chem. 2006 Dec 08; 281(49):37952-61. PMID: 16984912.
      Citations: 14     Fields:    Translation:Cells
    89. Badorrek CS, Gherghe CM, Weeks KM. Structure of an RNA switch that enforces stringent retroviral genomic RNA dimerization. Proc Natl Acad Sci U S A. 2006 Sep 12; 103(37):13640-5. PMID: 16945907.
      Citations: 29     Fields:    Translation:Cells
    90. Bokinsky G, Nivón LG, Liu S, Chai G, Hong M, Weeks KM, Zhuang X. Two distinct binding modes of a protein cofactor with its target RNA. J Mol Biol. 2006 Aug 25; 361(4):771-84. PMID: 16872630.
      Citations: 35     Fields:    Translation:AnimalsCells
    91. Wilkinson KA, Merino EJ, Weeks KM. Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution. Nat Protoc. 2006; 1(3):1610-6. PMID: 17406453.
      Citations: 386     Fields:    Translation:Cells
    92. Li TW, Weeks KM. Structure-independent and quantitative ligation of single-stranded DNA. Anal Biochem. 2006 Feb 15; 349(2):242-6. PMID: 16325753.
      Citations: 12     Fields:    Translation:Cells
    93. Gherghe CM, Krahn JM, Weeks KM. Crystal structures, reactivity and inferred acylation transition states for 2'-amine substituted RNA. J Am Chem Soc. 2005 Oct 05; 127(39):13622-8. PMID: 16190727.
      Citations: 3     Fields:    Translation:Cells
    94. Merino EJ, Weeks KM. Facile conversion of aptamers into sensors using a 2'-ribose-linked fluorophore. J Am Chem Soc. 2005 Sep 21; 127(37):12766-7. PMID: 16159247.
      Citations: 5     Fields:    Translation:Cells
    95. Longo A, Leonard CW, Bassi GS, Berndt D, Krahn JM, Hall TM, Weeks KM. Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase. Nat Struct Mol Biol. 2005 Sep; 12(9):779-87. PMID: 16116439.
      Citations: 14     Fields:    Translation:Cells
    96. Badorrek CS, Weeks KM. RNA flexibility in the dimerization domain of a gamma retrovirus. Nat Chem Biol. 2005 Jul; 1(2):104-11. PMID: 16408007.
      Citations: 27     Fields:    Translation:Cells
    97. Wilkinson KA, Merino EJ, Weeks KM. RNA SHAPE chemistry reveals nonhierarchical interactions dominate equilibrium structural transitions in tRNA(Asp) transcripts. J Am Chem Soc. 2005 Apr 06; 127(13):4659-67. PMID: 15796531.
      Citations: 86     Fields:    Translation:Cells
    98. Merino EJ, Wilkinson KA, Coughlan JL, Weeks KM. RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE). J Am Chem Soc. 2005 Mar 30; 127(12):4223-31. PMID: 15783204.
      Citations: 377     Fields:    Translation:Cells
    99. Buchmueller KL, Weeks KM. Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies. Nucleic Acids Res. 2004 Dec 15; 32(22):e184. PMID: 15601995.
      Citations: 5     Fields:    Translation:Cells
    100. Garcia I, Weeks KM. Structural basis for the self-chaperoning function of an RNA collapsed state. Biochemistry. 2004 Dec 07; 43(48):15179-86. PMID: 15568809.
      Citations: 6     Fields:    Translation:Cells
    101. John DM, Merino EJ, Weeks KM. Mechanics of DNA flexibility visualized by selective 2'-amine acylation at nucleotide bulges. J Mol Biol. 2004 Mar 26; 337(3):611-9. PMID: 15019781.
      Citations: 2     Fields:    Translation:Cells
    102. Buchmueller KL, Weeks KM. Near native structure in an RNA collapsed state. Biochemistry. 2003 Dec 02; 42(47):13869-78. PMID: 14636054.
      Citations: 19     Fields:    Translation:Cells
    103. Merino EJ, Weeks KM. Fluorogenic resolution of ligand binding by a nucleic acid aptamer. J Am Chem Soc. 2003 Oct 15; 125(41):12370-1. PMID: 14531655.
      Citations: 8     Fields:    Translation:Humans
    104. Buchmueller KL, Hill BT, Platz MS, Weeks KM. RNA-tethered phenyl azide photocrosslinking via a short-lived indiscriminant electrophile. J Am Chem Soc. 2003 Sep 10; 125(36):10850-61. PMID: 12952464.
      Citations: 10     Fields:    Translation:Cells
    105. Bassi GS, Weeks KM. Kinetic and thermodynamic framework for assembly of the six-component bI3 group I intron ribonucleoprotein catalyst. Biochemistry. 2003 Aug 26; 42(33):9980-8. PMID: 12924947.
      Citations: 10     Fields:    Translation:AnimalsCells
    106. Garcia I, Weeks KM. Small structural costs for evolution from RNA to RNP-based catalysis. J Mol Biol. 2003 Aug 01; 331(1):57-73. PMID: 12875836.
      Citations: 1     Fields:    Translation:AnimalsCells
    107. Chamberlin SI, Weeks KM. Differential helix stabilities and sites pre-organized for tertiary interactions revealed by monitoring local nucleotide flexibility in the bI5 group I intron RNA. Biochemistry. 2003 Feb 04; 42(4):901-9. PMID: 12549908.
      Citations: 8     Fields:    Translation:Cells
    108. Chamberlin SI, Merino EJ, Weeks KM. Catalysis of amide synthesis by RNA phosphodiester and hydroxyl groups. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14688-93. PMID: 12403820.
      Citations: 11     Fields:    Translation:Cells
    109. John DM, Weeks KM. Chemical interrogation of mismatches in DNA-DNA and DNA-RNA duplexes under nonstringent conditions by selective 2'-amine acylation. Biochemistry. 2002 May 28; 41(21):6866-74. PMID: 12022892.
      Citations: 3     Fields:    Translation:Cells
    110. Bassi GS, de Oliveira DM, White MF, Weeks KM. Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):128-33. PMID: 11773622.
      Citations: 23     Fields:    Translation:AnimalsCells