"Splicing Factor U2AF" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2 SMALL NUCLEAR to the splice site and mediates interactions between it, the RNA molecule, and other splicing factors for accurate 3'-splice site selection.
| Descriptor ID |
D000072668
|
| MeSH Number(s) |
D12.776.157.725.829.750 D12.776.664.962.829.750
|
| Concept/Terms |
Splicing Factor U2AF- Splicing Factor U2AF
- Factor U2AF, Splicing
- U2AF, Splicing Factor
- U2AF 65
- U2AF(65)
- U2AF Splicing Factor
- Factor, U2AF Splicing
- Splicing Factor, U2AF
|
Below are MeSH descriptors whose meaning is more general than "Splicing Factor U2AF".
Below are MeSH descriptors whose meaning is more specific than "Splicing Factor U2AF".
This graph shows the total number of publications written about "Splicing Factor U2AF" by people in this website by year, and whether "Splicing Factor U2AF" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Splicing Factor U2AF" by people in Profiles.
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Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia. Nat Commun. 2018 09 07; 9(1):3649.
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Clonogenic versus morphogenic mutations in myeloid neoplasms: chronologic observations in a U2AF1, TET2, CSF3R and JAK2 'co-mutated' myeloproliferative neoplasm suggest a hierarchical order of mutations and potential predictive value for kinase inhibitor treatment response. Leuk Lymphoma. 2018 08; 59(8):1994-1997.
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Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis. J Hematol Oncol. 2017 05 02; 10(1):99.
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The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes. J Clin Invest. 2017 Jun 01; 127(6):2206-2221.
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Integrated structural biology to unravel molecular mechanisms of protein-RNA recognition. Methods. 2017 04 15; 118-119:119-136.