"Perilipin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
| Descriptor ID |
D000070780
|
| MeSH Number(s) |
D12.776.157.464.500.750
|
| Concept/Terms |
Perilipin-2- Perilipin-2
- Perilipin 2
- ADRP Protein
- Adipose Differentiation-Related Protein
- Adipose Differentiation Related Protein
- Protein, Adipose Differentiation-Related
- PLIN2 Protein
- Protein, PLIN2
- Perilipin 2 Protein
- Protein, Perilipin 2
- Adipophilin
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-2".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-2".
This graph shows the total number of publications written about "Perilipin-2" by people in this website by year, and whether "Perilipin-2" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
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Below are the most recent publications written about "Perilipin-2" by people in Profiles.
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Long-chain metabolites of vitamin E: Interference with lipotoxicity via lipid droplet associated protein PLIN2. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 08; 1863(8):919-927.
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Perilipin 2 levels are increased in patients with in-stent neoatherosclerosis: A clue to mechanisms of accelerated plaque formation after drug-eluting stent implantation. Int J Cardiol. 2018 05 01; 258:55-58.
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Microcystic adnexal carcinoma with sebaceous differentiation: Three cases. J Cutan Pathol. 2018 Apr; 45(4):290-295.
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Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice. FASEB J. 2017 11; 31(11):4971-4984.
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Purification, crystallization and preliminary crystallographic analysis of avian infectious bronchitis virus nsp3 ADRP domain. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Sep 01; 64(Pt 9):802-4.
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Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals. Stroke. 2007 Jun; 38(6):1791-8.