Immunoglobulin Light-chain Amyloidosis
"Immunoglobulin Light-chain Amyloidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
| Descriptor ID |
D000075363
|
| MeSH Number(s) |
C04.557.595.250 C18.452.845.500.550 C20.683.515.507 C20.683.780.565
|
| Concept/Terms |
Immunoglobulin Light-chain Amyloidosis- Immunoglobulin Light-chain Amyloidosis
- Immunoglobulin Light chain Amyloidosis
- Immunoglobulin Light-chain Amyloidoses
- Amyloidosis, Primary
- AL Amyloidosis
- AL Amyloidoses
- Primary Systemic Amyloidosis
- Amyloidoses, Primary Systemic
- Amyloidosis, Primary Systemic
- Primary Systemic Amyloidoses
- Systemic Amyloidoses, Primary
- Systemic Amyloidosis, Primary
- Amyloidosis, Immunoglobulin Light-chain
- Amyloidosis, Immunoglobulin Light chain
- Primary Amyloidosis
- Amyloidoses, Primary
- Primary Amyloidoses
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Light-chain Amyloidosis".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Light-chain Amyloidosis".
This graph shows the total number of publications written about "Immunoglobulin Light-chain Amyloidosis" by people in this website by year, and whether "Immunoglobulin Light-chain Amyloidosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 13 | 2 | 15 |
| 2018 | 11 | 1 | 12 |
| 2019 | 6 | 0 | 6 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Immunoglobulin Light-chain Amyloidosis" by people in Profiles.
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The impact of COVID-19 in the management of AL amyloidosis and Immunoglobulin Deposition Disease: A single-center experience. Eur J Haematol. 2021 Mar; 106(3):340-345.
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Myeloma care adaptations in the UK during SARS-CoV-2 pandemic: Challenges and measurable outcomes. Eur J Haematol. 2020 Nov; 105(5):662-666.
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Challenges in the management of patients with systemic light chain (AL) amyloidosis during the COVID-19 pandemic. Br J Haematol. 2020 08; 190(3):346-357.
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Reactive Vasodilation Predicts Mortality in Primary Systemic Light-Chain Amyloidosis. Circ Res. 2019 09 27; 125(8):744-758.
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Cardiac biomarkers are prognostic in systemic light chain amyloidosis with no cardiac involvement by standard criteria. Haematologica. 2020 05; 105(5):1405-1413.
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Pharyngo-laryngeal involvement in systemic amyloidosis with cardiac involvement: a prospective observational study. Amyloid. 2019 Dec; 26(4):216-224.
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Cardiorenal AL amyloidosis: risk stratification and outcomes based upon cardiac and renal biomarkers. Br J Haematol. 2019 08; 186(3):460-470.
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Efficacy of lenalidomide as salvage therapy for patients with AL amyloidosis. Amyloid. 2018 Dec; 25(4):234-241.
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A pilot study demonstrating cardiac uptake with 18F-florbetapir PET in AL amyloidosis patients with cardiac involvement. Amyloid. 2018 Dec; 25(4):247-252.
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Flow cytometry for fast screening and automated risk assessment in systemic light-chain amyloidosis. Leukemia. 2019 05; 33(5):1256-1267.