Mucosal-Associated Invariant T Cells
"Mucosal-Associated Invariant T Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of T-lymphocytes that are present in large numbers at MUCOUS MEMBRANES and respond to INFECTIONS. They express a conserved invariant T-CELL RECEPTOR ALPHA-CHAIN that enables them to respond to infections by sensing RIBOFLAVIN metabolites of pathogens.
| Descriptor ID |
D000072336
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| MeSH Number(s) |
A11.118.637.555.567.550.500.100 A11.118.637.555.567.569.500.100 A15.145.229.637.555.567.550.500.100 A15.145.229.637.555.567.569.500.100 A15.382.490.555.567.550.500.100 A15.382.490.555.567.569.500.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mucosal-Associated Invariant T Cells".
Below are MeSH descriptors whose meaning is more specific than "Mucosal-Associated Invariant T Cells".
This graph shows the total number of publications written about "Mucosal-Associated Invariant T Cells" by people in this website by year, and whether "Mucosal-Associated Invariant T Cells" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 5 | 1 | 6 |
| 2018 | 9 | 0 | 9 |
| 2019 | 3 | 0 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 5 | 0 | 5 |
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Below are the most recent publications written about "Mucosal-Associated Invariant T Cells" by people in Profiles.
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Suppressive Monocytes Impair MAIT Cells Response via IL-10 in Patients with Severe COVID-19. J Immunol. 2021 10 01; 207(7):1848-1856.
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Single-Cell Transcriptomic Profiling of MAIT Cells in Patients With COVID-19. Front Immunol. 2021; 12:700152.
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In vitro Interleukin-7 treatment partially rescues MAIT cell dysfunction caused by SARS-CoV-2 infection. Sci Rep. 2021 07 08; 11(1):14090.
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Natural killer cells and unconventional T cells in COVID-19. Curr Opin Virol. 2021 08; 49:176-182.
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COVID-19 severity and obesity: are MAIT cells a factor? Lancet Respir Med. 2021 05; 9(5):445-447.
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Title of article: Mucosal-associated invariant T cells in lung diseases. Int Immunopharmacol. 2021 May; 94:107485.
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Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 Patients. Viruses. 2021 02 03; 13(2).
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Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity. Nat Immunol. 2021 03; 22(3):322-335.
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Biological functions of MAIT cells in tissues. Mol Immunol. 2021 02; 130:154-158.
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Phenotypical and functional alteration of unconventional T cells in severe COVID-19 patients. J Exp Med. 2020 12 07; 217(12).