"Hydrochlorothiazide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Descriptor ID |
D006852
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MeSH Number(s) |
D02.886.590.700.135.261.476 D02.886.655.500.261.476 D03.633.100.174.261.476
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydrochlorothiazide".
Below are MeSH descriptors whose meaning is more specific than "Hydrochlorothiazide".
This graph shows the total number of publications written about "Hydrochlorothiazide" by people in this website by year, and whether "Hydrochlorothiazide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2013 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
2017 | 4 | 3 | 7 |
2018 | 4 | 2 | 6 |
2019 | 3 | 1 | 4 |
2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Hydrochlorothiazide" by people in Profiles.
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Hydrochlorothiazide Use and Increased Squamous Cell Carcinoma Burden in a High-Risk Mohs Population: A Cross-Sectional Study. Dermatol Surg. 2020 05; 46(5):704-708.
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Severe hypocalcemia in a thyroidectomized woman with Covid-19 infection. Endocrine. 2020 May; 68(2):253-254.
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Reply to: "Thiazides and nonmelanoma skin cancer: Is it a class effect?" J Am Acad Dermatol. 2020 01; 82(1):e27.
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Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans. N Engl J Med. 2019 06 20; 380(25):2429-2439.
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Reply to "Comment on 'Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark'". J Am Acad Dermatol. 2021 12; 85(6):e359-e360.
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Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction. Curr Clin Pharmacol. 2019; 14(1):5-15.
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Hydrochlorothiazide and the Risk of Malignant Melanoma-Reply. JAMA Intern Med. 2018 10 01; 178(10):1425-1426.
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Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension. Am J Cardiol. 2018 11 01; 122(9):1496-1505.
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Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma. JAMA Intern Med. 2018 08 01; 178(8):1120-1122.
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Hydrochlorothiazide use and risk for Merkel cell carcinoma and malignant adnexal skin tumors: A nationwide case-control study. J Am Acad Dermatol. 2019 Feb; 80(2):460-465.e9.